Sequence 1: | NP_001261962.1 | Gene: | Abl / 45821 | FlyBaseID: | FBgn0000017 | Length: | 1723 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_038510.2 | Gene: | Btk / 12229 | MGIID: | 88216 | Length: | 659 | Species: | Mus musculus |
Alignment Length: | 490 | Identity: | 192/490 - (39%) |
---|---|---|---|
Similarity: | 281/490 - (57%) | Gaps: | 38/490 - (7%) |
- Green bases have known domain annotations that are detailed below.
Fly 187 SAHRWTSKENLLAPGPEED---------DP----------QLFVALYDFQAGGENQLSLKKGEQV 232
Fly 233 RILSYNKSGEWCEAHSDSGNVGWVPSNYVTPL-NSLEKHSWYHGPISRNAAEYLL-SSGINGSFL 295
Fly 296 VRESESSPGQRSISL------RYEGRVYHYRISEDPDGKVFVTQEAKFNTLAELVHHHSVPHEGH 354
Fly 355 GLITPLLYPAPKQNKPTVFPLSPEPDEWEICRTDIMMKHKLGGGQYGEVYEAVWK-RYGNTVAVK 418
Fly 419 TLKEDTMALKDFLEEAAIMKEMKHPNLVQLIGVCTREPPFYIITEFMSHGNLLDFLRSAGRETLD 483
Fly 484 AVALLYMATQIASGMSYLESRNYIHRDLAARNCLVGDNKLVKVADFGLARLMRDDTYTAHAGAKF 548
Fly 549 PIKWTAPEGLAYNKFSTKSDVWAFGVLLWEIATYGMSPYPAIDLTDVYHKLDKGYRMERPPGCPP 613
Fly 614 EVYDLMRQCWQWDATDRPTFK-SIHHALEHMFQES 647 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
Abl | NP_001261962.1 | SH3_Abl | 209..263 | CDD:212784 | 21/53 (40%) |
SH2_ABL | 268..363 | CDD:198189 | 31/101 (31%) | ||
PTKc_Abl | 382..644 | CDD:270645 | 117/263 (44%) | ||
Pkinase_Tyr | 389..640 | CDD:285015 | 112/252 (44%) | ||
FABD | 1584..1723 | CDD:197885 | |||
Btk | NP_038510.2 | PH_Btk | 6..166 | CDD:269944 | |
Inositol-(1,3,4,5)-tetrakisphosphate 1-binding. /evidence=ECO:0000250 | 12..24 | ||||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 171..210 | 12/32 (38%) | |||
SH3_BTK | 217..271 | CDD:212839 | 21/54 (39%) | ||
SH2_Tec_Btk | 274..378 | CDD:198260 | 34/106 (32%) | ||
PTKc_Btk_Bmx | 397..652 | CDD:173657 | 114/257 (44%) | ||
Inhibitor-binding. /evidence=ECO:0000250 | 474..479 | 3/4 (75%) | |||
CAV1-binding. /evidence=ECO:0000250 | 581..588 | 6/6 (100%) | |||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 0 | 0.000 | Not matched by this tool. | |||
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 1 | 1.010 | - | - | D1047190at2759 | |
OrthoFinder | 1 | 1.000 | - | - | FOG0000006 | |
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
3 | 2.920 |