Protein Alignment Abl and LOC100496572

DIOPT Version :10

• Sequence 1: NP_001261962.1
• Gene: Abl / 45821
• FlyBaseID: FBgn0000017
• Length: 1723
• Species: Drosophila melanogaster
• Sequence 2: NP_001415012.1
• Gene: LOC100496572 / 100496572
• XenbaseID: XB-GENE-29083231
• Length: 1368
• Species: Xenopus tropicalis
• Alignment Length: 775
• Identity: 203/775 - (26%)
• Similarity: 304/775 - (39%)
• Gaps: 211/775 - (27%)

  Fly    18 SGAP------VSCIGLS--SSPVASVSPHCISSSSGVSSAPLGGGS--TLRGSRIKSSSSGVASG 72
            :|.|      :|..|.:  ...:.|:.|         :..||.||:  ||:|..::|..:.....
 Frog   639 TGTPYYIKGTISAAGFNFVEPAITSIEP---------NFGPLAGGTMLTLKGQNLRSGETQRVFI 694

  Fly    73 SGSGGGGGGSGSG------LSQRSGGHKDARCNPTVG-LNIFTEHNGTKHSSFRGHPGKYHMNLE 130
            ||:.....||...      :|.||         .::| ||:....:|.:.||    |.::
 Frog   695 SGAECMISGSLCPAEVLCCVSPRS---------LSLGPLNVSALLDGAEISS----PAQF----- 741

  Fly   131 ALLQSRPLPHIPAGSTAASLLADAAELQQHQQDSGGLGLQGSSLGG------GHSSTTSVFESAH 189
               |.:|.|.:.......||.:...           |.:|||:|..      .:|...:|.....
 Frog   742 ---QYKPDPLVSVIRPNCSLASGTR-----------LTIQGSNLDSVSSIKISYSGQKTVSSDCQ 792

  Fly   190 RWTSKENLLAPGPEED------------DPQLFVALYDFQ---------------AGGENQLSLK 227
            ...|.:.::...||..            |...::..|.|:               .||  .|.||
 Frog   793 GTFSSDRIVCRSPEYPYFGRPGNLTLALDAVNYIYPYRFRYLQNYVIHPFRPKDPDGG--ILKLK 855

  Fly   228 KG-----------EQVRI---LSYNKSGEWCEAHSDSGNVGW-VPSNYVTP-------------- 263
            ||           |||..   :|....|..|........:.. :|...|.|
 Frog   856 KGEDEIETHQENLEQVATCLKVSMTVGGRECNPTVLKNEITCRIPKGMVIPSEGSIVQVCVDDDC 920

  Fly   264 --------LNSLEKHSWYHGPISRNAAEYLLSSGINGSFLV----RESESSPGQRSISLRYEGR- 315
                    :|.|:.   ..|.:..:.|..|:.:.:  .||:    |:.:..|...::.|.....
 Frog   921 TTVGLVMIVNMLDP---VLGIVLGSVASVLVVAVL--IFLLLKHQRKKKKKPAVEALELLSNNNR 980

  Fly   316 --------VYH--YRISEDPDGKVFVTQEAKFNTLAELVH--HHSVPHEGHG----LITPLLYPA 364
                    :.|  ||.|..|..          |:...|.|  .:|....|.|    |:|.||...
 Frog   981 EPVLSPISLLHVDYRTSYIPSS----------NSGGMLSHGAGYSGGSLGGGSMPILLTSLLDSL 1035

  Fly   365 P----KQNKPTVFPLSPEPDEWEICRTDIMMKHK---LGGGQYGEVYEAVWKRYGNTV------- 415
            .    ::.|..:.|        |.|.|    .|:   :|.|.:|.||      :|..|
 Frog  1036 RPELLEEVKDVLIP--------ERCLT----THRDRIIGKGHFGSVY------HGTYVDEDQQEV 1082

  Fly   416 --AVKTLKE--DTMALKDFLEEAAIMKEMKHPNLVQLIGV-CTREPPFYIITEFMSHGNLLDFLR 475
              |||:|..  |...:::||.|..:||...|||::.|||: ..:|....::..||.||:|..|:|
 Frog  1083 HCAVKSLNRITDLEEVEEFLREGILMKSFHHPNVLSLIGIFLPQEGLPLVVLPFMKHGDLRHFIR 1147

  Fly   476 SAGRETLDAVALLYMATQIASGMSYLESRNYIHRDLAARNCLVGDNKLVKVADFGLARLMRDDTY 540
            ...|.. ....|:....|::.||.||.:|.::|||||||||::.:...||||||||||.:.|..|
 Frog  1148 CQERNP-TVKDLVGFGLQVSRGMEYLANRKFVHRDLAARNCMLDETFHVKVADFGLARDVFDKEY 1211

  Fly   541 TA---HAGAKFPIKWTAPEGLAYNKFSTKSDVWAFGVLLWEIATYGMSPYPAIDLTDVYHKLDKG 602
            .:   |..|:.|:||.|.|.|...||:||||||:|||||||:.|.|..|||.:|..|:...|.:|
 Frog  1212 YSVRRHKNARLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVDPYDITRYLFRG 1276

  Fly   603 YRMERPPGCPPEVYDLMRQCWQWDATDRPTFKSIHHALEHMFQESSITEAVEKQLNANAT 662
            .|:.:|..||..:|.||..||.....:||||..:...:|.:    |.:...:..:|.|.|
 Frog  1277 RRLAQPEYCPDPLYSLMLSCWNPQPEERPTFTQLVGDMEVI----SNSLCGDHYINLNVT 1332

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Abl	NP_001261962.1	SH3_Abl	209..263	CDD:212784	17/83 (20%)
		SH2_ABL	268..363	CDD:198189	23/115 (20%)
		PTKc_Abl	382..644	CDD:270645	110/279 (39%)
		FABD	1584..1723	CDD:197885
LOC100496572	NP_001415012.1	None