Protein Alignment onecut and Onecut3

DIOPT Version :9

• Sequence 1: NP_001259065.1
• Gene: onecut / 45816
• FlyBaseID: FBgn0028996
• Length: 1081
• Species: Drosophila melanogaster
• Sequence 2: NP_631972.2
• Gene: Onecut3 / 246086
• MGIID: 1891409
• Length: 490
• Species: Mus musculus
• Alignment Length: 681
• Identity: 196/681 - (28%)
• Similarity: 241/681 - (35%)
• Gaps: 330/681 - (48%)

  Fly   328 SPGFSQTSYATLTPIQPLPPISTMSEKFAYSGHISGGDSGDTDVNGDGAGGGVVEVGEVTNQSSE 392
            :||...| |.||||:|.|||::.:::||  ..|...|..|
Mouse    97 APGLGGT-YTTLTPLQHLPPLAAVADKF--HQHAVAGAHG------------------------- 133

  Fly   393 ATGTVSISSGNATSSVCSNNDCSSFSALSMPIGSGHLGLGVLSGVQSPFSSYEKLSSMISPPPNN 457
                                              ||           |.:.....::...|||..
Mouse   134 ----------------------------------GH-----------PHAHPHPATAPPPPPPQR 153

  Fly   458 YLVSCDLHSSVSGRVINSSHLQLSHNGNKKESGTHEHTHRPADVNGGKFSYTGHISRGDSVDNDV 522
                  |.:||||                  |.|.....|.|      .:..||
Mouse   154 ------LAASVSG------------------SFTLMRDERAA------LASVGH----------- 177

  Fly   523 NGEKFSFSDHISGGDSGDEDANREKFIYSDHISEGENGPDVNSGTNWLQMHSEREVRLHMPVPAE 587
                                      :|..:   |:..|.:.|..:              |:|:.
Mouse   178 --------------------------LYGPY---GKELPTMGSPLS--------------PLPSA 199

  Fly   588 LEARFHISSERRTRLNVPPARGSLSRHLAPNAPICPADWKADDWKHSNAGVVSLTADMPVVVSLT 652
            |                |||     .|.||.                                 .
Mouse   200 L----------------PPA-----LHSAPQ---------------------------------P 210

  Fly   653 PTPPPLRDDSVSGIKQNERSSPGHREQYFLDKSQEPSSVVADQCSPGINGTPQSVCVIHQQSPSA 717
            |.||||.          ...:|||              :..|:..|.....|.:..:...:...|
Mouse   211 PPPPPLA----------AYGAPGH--------------LAGDKLLPPAAFEPHAALLGRAEDALA 251

  Fly   718 LG-------------------------NGFQSSSQQAKVSSCASPKGTVSSGGAVSNRIANSSDM 757
            .|                         .|..::......|....|.|...:||......|.:: .
Mouse   252 RGLPGGGGGAGGGGAAGGAAAGLLAPLGGLAAAGAHGPHSGGGGPGGGGGAGGGSGGPGAGAA-A 315

  Fly   758 EEINTKDLAQRISAELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMYKWL 822
            ||||||::||||:||||||||||||||||:|||||||||||||||||||||||||||||||:|||
Mouse   316 EEINTKEVAQRITAELKRYSIPQAIFAQRILCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWL 380

  Fly   823 QEPEFQRMSALRMAAAQIPQRAPLSSGMSLGSATGPSGSTGTIPTDLDPHGGPTMIQNPLTNESD 887
            ||||||||||||:||
Mouse   381 QEPEFQRMSALRLAA-------------------------------------------------- 395

  Fly   888 SSPASTPVTSVLVGSVVSCRRKE-EPQIEQMPQPKKPRLVFTDLQRRTLQAIFKETKRPSKEMQV 951
                              |:||| :.|.|:..||||.||||||||||||.|||||.||||||||.
Mouse   396 ------------------CKRKEQDQQKERALQPKKQRLVFTDLQRRTLIAIFKENKRPSKEMQA 442

  Fly   952 TIARQLGLEPTTVGNFFMNARRRSMDKWRDD 982
            ||::|||||..||.|||||||||.|::|.::
Mouse   443 TISQQLGLELNTVSNFFMNARRRCMNRWAEE 473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
onecut	NP_001259065.1	CUT	756..830	CDD:280527	66/73 (90%)
		HOX	920..975	CDD:197696	45/54 (83%)
Onecut3	NP_631972.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	130..155		8/100 (8%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	193..213		10/87 (11%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	287..316		6/29 (21%)
		CUT	316..388	CDD:280527	66/71 (93%)
		HOX	411..466	CDD:197696	45/54 (83%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167835043
Domainoid	1	1.000	148	1.000	Domainoid score	I4442
eggNOG	1	0.900	-	-		E1_KOG2252
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001166
OrthoInspector	1	1.000	-	-		otm43997
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR14057
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X793
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.800