Protein Alignment onecut and ceh-48

DIOPT Version :10

• Sequence 1: NP_524842.2
• Gene: onecut / 45816
• FlyBaseID: FBgn0028996
• Length: 1081
• Species: Drosophila melanogaster
• Sequence 2: NP_501046.1
• Gene: ceh-48 / 182756
• WormBaseID: WBGene00015934
• Length: 459
• Species: Caenorhabditis elegans
• Alignment Length: 779
• Identity: 212/779 - (27%)
• Similarity: 274/779 - (35%)
• Gaps: 386/779 - (49%)

  Fly   261 DNGHGEVLS---------VIVHSQDSDKEDCEENDDGDAEGDLENEDDDERDSR--SREQLLSHS 314
            |:|...:||         .|:...|....:|::.||...|...:|...|..|..  ..|:.||..
 Worm     6 DSGSDPLLSAALGSPIHHAILSMDDEVDGNCDDVDDISPESHHDNHFIDFTDDLVVQTERNLSKK 70

  Fly   315 SYQTLTSVNDRLSSPGFSQTSYATLTPIQPLPPISTMSEKFAYSGHISGGDSGDTDVNGDGAGGG 379
            .     ..::|.:..|:.  :|||||.:||||||||
 Worm    71 G-----RTSNRNARQGYD--NYATLTNLQPLPPIST----------------------------- 99

  Fly   380 VVEVGEVTNQSSEATGTVSISSGNATSSVCSNNDCSSFSALSMPIGSGHLGLGVLSGVQSPFSSY 444
                  ||::|::                                            ||.|
 Worm   100 ------VTSKSTK--------------------------------------------VQRP---- 110

  Fly   445 EKLSSMISPPPNNYLVSCDLHSSVSGRVINSSH-LQLSHNGNKKESGTHEHTHRPADVNGGKFSY 508
                   ||.||.|..:..          |||: ::.....:..|..||. :..|:|
 Worm   111 -------SPSPNFYFPTSS----------NSSYDMKYEEEEDDCEGITHS-SSSPSD-------- 149

  Fly   509 TGHISRGDSVDNDVNGEKFSFSDHISGGDSGDEDANREKFIYSDHISEGENGPDVNSGTNWLQMH 573
                                ||:|                           |.|:|.
 Worm   150 --------------------FSNH---------------------------GTDLNH-------- 159

  Fly   574 SEREVRLHMPVPAELEARFHISSERRTRLNVPPARGSLSRHLAPNAPICPADWKADDWKHSNAGV 638
                     |..|.....|.:::
 Worm   160 ---------PFSASSFDSFDVTT------------------------------------------ 173

  Fly   639 VSLTADMPVVVSLTPTPPPLRDDSVSGIKQNERSSPGHREQYFLDKSQEPSSVVADQCSPGINGT 703
            ||.||...::.|                           ...|:.:.||     ||..:....||
 Worm   174 VSTTATSTIMNS---------------------------TDKFIARIQE-----ADSTTKSPKGT 206

  Fly   704 PQSVCVIHQQSPSALGNGFQSSSQQAKVSSCASPKGTVSSGGAVSNRIANSSDMEEINTKDLAQR 768
                      ||:||.:|           .|..                :..|.||:|||:||.:
 Worm   207 ----------SPAALMHG-----------HCEE----------------DFDDGEELNTKELALQ 234

  Fly   769 ISAELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMYKWLQEPEFQRMSAL 833
            |:||||||||||||||:|||||||||||||||||||||||||||||||||.|||:||||||||||
 Worm   235 IAAELKRYSIPQAIFAERVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMAKWLEEPEFQRMSAL 299

  Fly   834 RMAAAQIPQRAPLSSGMSLGSATGPSGSTGTIPTDLDPHGGPTMIQNPLTNESDSSPASTPVTSV 898
            |:||
 Worm   300 RLAA------------------------------------------------------------- 303

  Fly   899 LVGSVVSCRRKEE---PQIEQMPQPKKPRLVFTDLQRRTLQAIFKETKRPSKEMQVTIARQLGLE 960
                   |:||||   |...||..|||.||||:|:|||||||||:||||||:|||:||::||.|:
 Worm   304 -------CKRKEEHTTPNSPQMVVPKKTRLVFSDIQRRTLQAIFRETKRPSREMQITISQQLNLD 361

  Fly   961 PTTVGNFFMNARRRSMD-KWRDDDSKS-----TMHVAHSRQQQDEQQKDNAHTHSQSQIQDQNH 1018
            ||||.|||||||||..| |....:|:.     ::|..||      ....:|.:.|.|.:|..|:
 Worm   362 PTTVANFFMNARRRGHDLKQETSESEERSEEPSIHFEHS------ASSSSASSSSSSSMQLDNY 419

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
onecut	NP_524842.2	CUT	756..830	CDD:460543	64/73 (88%)
		HOX	920..975	CDD:197696	43/54 (80%)
ceh-48	NP_501046.1	CUT	222..296	CDD:460543	64/73 (88%)
		HOX	321..375	CDD:197696	42/53 (79%)