Protein Alignment onecut and onecut3

DIOPT Version :9

• Sequence 1: NP_001259065.1
• Gene: onecut / 45816
• FlyBaseID: FBgn0028996
• Length: 1081
• Species: Drosophila melanogaster
• Sequence 2: XP_002938867.1
• Gene: onecut3 / 100491290
• XenbaseID: XB-GENE-484505
• Length: 439
• Species: Xenopus tropicalis
• Alignment Length: 770
• Identity: 207/770 - (26%)
• Similarity: 270/770 - (35%)
• Gaps: 394/770 - (51%)

  Fly   257 EMGLDN-GHGEVLSVIVHSQDSDKEDCEENDDGDAEGDLENEDDDERDSRSREQLLSHSSYQTLT 320
            |:.::| |:   |..:.|||               .|::.:.....:.  |...|:||.....:|
 Frog     2 ELTMENLGN---LHSVTHSQ---------------AGEIMSSSHSRQP--SHRNLVSHGRPAMVT 46

  Fly   321 SV----------NDRLSSP-------------GFSQTS-YATLTPIQPLPPISTMSEKFAYSGH- 360
            |:          ::.|..|             |.|.:| |.||||:|.||||||:|:||.:..|
 Frog    47 SMTSILDGGEYRSEHLGGPLHPAMNMSCESPSGMSLSSTYTTLTPLQHLPPISTVSDKFHHPHHH 111

  Fly   361 ---------ISGGDSGDTDVNGDGAGGGVVEVGEVTNQSSEATGTVSISSGNATSSVCSNNDCSS 416
                     ::|..||...:..|..  |:..:|.:.....:                       .
 Frog   112 HHHHHHHQRLAGNVSGSFTLMRDER--GLASMGNLYGHYPK-----------------------D 151

  Fly   417 FSALSMPIGSGHLGLGVLSGVQSPFSSY--------EKLSSMISPPPNNYLVSCDLHSSVSGRVI 473
            .:.:..|:.....|||.|...|.....|        ||:.|     ||::    |.|:::
 Frog   152 MTTMGQPLSPLSNGLGTLHNSQQSLGPYGPGGHLSNEKMLS-----PNSF----DSHAAM----- 202

  Fly   474 NSSHLQLSHNGNKKESGTHEHTHRPADVNGGKFSYTGHISRGDSVDNDVNGEKFSFSDHISGGDS 538
                                                  :||.:
 Frog   203 --------------------------------------LSRSE---------------------- 207

  Fly   539 GDEDANREKFIYSDHISEGENGPDVNSGTNWLQMHSEREVRLHMPVPAELEARFHISSERRTRLN 603
                         ||::.|..||
 Frog   208 -------------DHLTRGLGGP------------------------------------------ 217

  Fly   604 VPPARGSLSRHLAPNAPICPADWKADDWKHSNAGVVSLTADMPVVVSLTPTPPPLRDDSVSGIKQ 668
                                           .||::                |||
 Frog   218 -------------------------------GAGMM----------------PPL---------- 225

  Fly   669 NERSSPGHREQYFLDKSQEPSSVVADQCSPGINGTPQSVCVIHQQSPSALGNGFQSSSQQAKVSS 733
            |.....||                                  |..|    .||.....::.:.|:
 Frog   226 NGMHPHGH----------------------------------HHVS----SNGSLLGDRERQAST 252

  Fly   734 CASPKGTVSSGGAVSNRIANSSDMEEINTKDLAQRISAELKRYSIPQAIFAQRVLCRSQGTLSDL 798
            ..|..|             .:..:||||||::||||:||||||||||||||||:|||||||||||
 Frog   253 SGSQAG-------------GNGQVEEINTKEVAQRITAELKRYSIPQAIFAQRILCRSQGTLSDL 304

  Fly   799 LRNPKPWSKLKSGRETFRRMYKWLQEPEFQRMSALRMAAAQIPQRAPLSSGMSLGSATGPSGSTG 863
            ||||||||||||||||||||:|||||||||||||||:||
 Frog   305 LRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAA-------------------------- 343

  Fly   864 TIPTDLDPHGGPTMIQNPLTNESDSSPASTPVTSVLVGSVVSCRRKE-EPQIEQMPQPKKPRLVF 927
                                                      |:||| |.|.::..||||.||||
 Frog   344 ------------------------------------------CKRKEQEQQKDRNLQPKKQRLVF 366

  Fly   928 TDLQRRTLQAIFKETKRPSKEMQVTIARQLGLEPTTVGNFFMNARRRSMDKWRDD 982
            ||||||||.|||||.||||||||:||::|||||..||.|||||||||.|::|::|
 Frog   367 TDLQRRTLIAIFKENKRPSKEMQITISQQLGLELNTVSNFFMNARRRCMNRWQED 421

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
onecut	NP_001259065.1	CUT	756..830	CDD:280527	66/73 (90%)
		HOX	920..975	CDD:197696	45/54 (83%)
onecut3	XP_002938867.1	CUT	262..332	CDD:367059	62/69 (90%)
		HOX	359..414	CDD:197696	45/54 (83%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	148	1.000	Domainoid score	I4427
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	305	1.000	Inparanoid score	I2600
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001166
OrthoInspector	1	1.000	-	-		otm49171
Panther	1	1.100	-	-	LDO	PTHR14057
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X793
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.060