Protein Alignment Spn27A and Serpina3a

DIOPT Version :9

• Sequence 1: NP_001260143.1
• Gene: Spn27A / 45815
• FlyBaseID: FBgn0028990
• Length: 447
• Species: Drosophila melanogaster
• Sequence 2: NP_001161177.1
• Gene: Serpina3a / 74069
• MGIID: 1921319
• Length: 422
• Species: Mus musculus
• Alignment Length: 402
• Identity: 109/402 - (27%)
• Similarity: 180/402 - (44%)
• Gaps: 42/402 - (10%)

  Fly    61 DIDTFVPFRSDSHDPFSWHLLKTV-LQNETADKNVIISPFSVKLVLALLAEAAGAGTQTQV---- 120
            |..|.....:|    |::.|.|.: |:|  ..||::.||.|:...|||::..|...|..::
Mouse    45 DSVTLASINTD----FAFSLYKKLALKN--PHKNIVFSPLSISAALALMSLGAKDNTLEEILEGL 103

  Fly   121 --ELANT-QTDIRSQNNVREFYRKTLNSFKKENQLHETLSVRTKLFTDSFIETQQKFTATLKHFY 182
              .|..| :.||. ||    |........:.|||:.  ::....||.|..::...:|....:..|
Mouse   104 KFNLTETPEADIH-QN----FGHLLQMLIQPENQVQ--INAGNALFIDKHLQILTEFKEKARALY 161

  Fly   183 DSEVEALDFTNPEAAADAINAWAANITQGRLQQLVAPDNVRSSVMLLTNLIYFNGLWRRQF--AT 245
            .:|....||..|..|...||.:....|||::::||: |..|::.|.|.|.:.|.|.|...|  ..
Mouse   162 KAEAFTADFQLPREATKLINDYVRKQTQGKIKELVS-DLHRNTSMALVNFLNFQGFWNVTFDPED 225

  Fly   246 TFQGSFFRSKDDQSRAEFME----QTDYFYYTTSEKLKAQILRLPYKGKNSLFVLLPYALNGIHD 306
            ||.|:|...:........|:    .|:||   ..|::::.::.|.|.|..|...:|| ....|..
Mouse   226 TFLGNFTLDRKRTVNVPMMKTEELTTNYF---RDEEMQSTVMELNYIGNASFLFILP-DQGRIQH 286

  Fly   307 LVKNLENDELKSAQWAME---EVKVKVTLPKFHFDYQQNLKETLRSLGVREIFEDSASLPGLTRG 368
            :..:|:...|:  :|...   .:..:::||||......||.:.|..||::|:|...|.|.|:|.
Mouse   287 VEDSLQPQSLR--KWRKSLRPRMLDELSLPKFSLSQDYNLNDILPELGIKEVFSTQADLSGITG- 348

  Fly   369 ADVAGKVKVSNILQKAGINVNEKGTEAYAATVVEIENKFGGSTAIEEFNVNRPFVFFIEEESTGN 433
               |..::||.::.:|.::|.|..|||...|:... |........:...|:|.|::.|.:....:
Mouse   349 ---AKNIRVSQMIHQAALDVTETHTEADVITIARY-NFQSAKIKAKIVKVDREFLYLILDPMFKS 409

  Fly   434 ILFAGKVHSPTT 445
            |...|||.:|.|
Mouse   410 ISVMGKVINPLT 421

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn27A	NP_001260143.1	SERPIN	72..440	CDD:238101	102/384 (27%)
Serpina3a	NP_001161177.1	SERPIN	53..416	CDD:294093	103/387 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S7561
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.050