DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn27A and serpinb14

DIOPT Version :9

Sequence 1:	NP_001260143.1	Gene:	Spn27A / 45815	FlyBaseID:	FBgn0028990	Length:	447	Species:	Drosophila melanogaster
Sequence 2:	XP_002665111.3	Gene:	serpinb14 / 569051	ZFINID:	ZDB-GENE-050506-148	Length:	437	Species:	Danio rerio

Alignment Length:	449	Identity:	120/449 - (26%)
Similarity:	203/449 - (45%)	Gaps:	91/449 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 SDSHDPFSWHLLKTVLQNETADKNVIISPFSVKLVLALLAEAA-------------------GAG 115
            |.::..||.:|.|.: ....|..||..||.|:...||:::..|                   .||
Zfish     5 SAANTQFSLNLFKKI-SGGNASGNVFYSPVSISSALAMVSLGAKGNTADQMFKVLGFNNLPKSAG 68

  Fly   116 TQTQVELANTQTDIRSQNNVREFYRKTL-------------------NSFKKENQLHE------- 154
            ...:...:..|...:.::.|::.:.:.:                   ...|.|.|:|.
Zfish    69 ATPEAHQSMMQQAQKPKSGVKDQHGQAMMQQTQKIDIPAELKKGSAVPGQKAEEQIHSNFNKFMS 133

  Fly   155 ---------TLSVRTKLFTDSFIETQQKFTATLKHFYDSEVEALDFTN-PEAAADAINAWAANIT 209
                     .||:..:|:.:...:..:||.:..|.:|::.:|.:||.| .|||...||.|....|
Zfish   134 ELNKPGAPYVLSLANRLYGEQTYQFVEKFLSDAKRYYEAGLEKVDFKNKSEAARVNINTWVEKNT 198

  Fly   210 QGRLQQLVAPDNVRSSV-MLLTNLIYFNGLWRRQF--ATTFQGSFFRSKDDQSRAEFMEQTDYFY 271
            |.:::.|:....:.:.. ::|.|.|||.|.|.|:|  ..|..|.|..:|:.....:.|.|..:|.
Zfish   199 QEKIKDLLPSGAIDAMTRLVLVNAIYFKGNWERKFPKEATNDGQFKLNKNQTKPVKMMYQKAHFP 263

  Fly   272 YTTSEKLKAQILRLPYKGKN-SLFVLLP----YALNGIHDLVKNLENDELKSAQWAMEEV----K 327
            ..:..::.:|:|.|||.||| |:.::||    .|..|:..|.|.|..::|  .:|...||    :
Zfish   264 LASIPEMNSQVLELPYVGKNLSMLIILPDQIEDATTGLEKLEKALTYEKL--MEWTKPEVMRQQE 326

  Fly   328 VKVTLPKFHFDYQQNLKETLRSLGVREIFE-DSASLPGLTRGADVAGKVKVSNILQKAGINVNEK 391
            |:|:||||..:...::|..|.|:|:.::|: ...:|.|::...|:.    :|.::.||.:.|||:
Zfish   327 VQVSLPKFKMEQTYDMKSLLVSMGMEDVFDPQKVNLTGMSSSNDLV----LSKVIHKAFVEVNEE 387

  Fly   392 GTEAYAATVVEIENKFGGSTAI-------EEFNVNRPFVFFIEEESTGNILFAGKVHSP 443
            ||||.|||         |:..:       :.||.:.||:|||....|.:|||.|:..||
Zfish   388 GTEAAAAT---------GAIMMLRCIRLPQSFNADHPFLFFIRHNPTKSILFYGRFCSP 437

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn27A	NP_001260143.1	SERPIN	72..440	CDD:238101	117/442 (26%)
serpinb14	XP_002665111.3	SERPIN	4..437	CDD:294093	118/447 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.020