DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn27A and serpina7

DIOPT Version :9

Sequence 1:	NP_001260143.1	Gene:	Spn27A / 45815	FlyBaseID:	FBgn0028990	Length:	447	Species:	Drosophila melanogaster
Sequence 2:	XP_021331940.1	Gene:	serpina7 / 564060	ZFINID:	ZDB-GENE-041010-47	Length:	425	Species:	Danio rerio

Alignment Length:	393	Identity:	107/393 - (27%)
Similarity:	190/393 - (48%)	Gaps:	26/393 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 IDTFVPFRSDSHDPFSWHLLKTVLQN-ETADKNVIISPFSVKLVLALLAEAAGAGTQTQVELANT 125
            |...:|...:.::.|::||.|.:::: :...||:..|||||.:.|:.|:..||..|:.|: |:..
Zfish    44 ISAKLPSLINMNNDFAFHLYKRLIESPDYQSKNIFFSPFSVSMALSELSLGAGGDTKQQL-LSGI 107

  Fly   126 --QTDIRSQNNVREFYRKTLNSFKKENQLHETLSVRTKLFTDSFIETQQKFTATLKHFYDSEVEA 188
              .:.|.|...:.:.:...|...  .|:....:.|.|.|:.....:...||...:|.||.|:...
Zfish   108 GYNSAIFSTEEMHQLFHSLLEEI--GNRTEVDIDVGTALYASDRFKPHSKFLEDMKEFYHSDGFT 170

  Fly   189 LDFTNPEAAADAINAWAANITQGRLQQLVAPDNV-RSSVMLLTNLIYFNGLWRRQF--ATTFQGS 250
            :||:..| ..|.||.:....|.|::.|.|  ||: :.::|.|...|||.|.|.:.|  .||.:.:
Zfish   171 VDFSVKE-TVDQINKYVEEKTHGKISQAV--DNLEKDTLMFLLTYIYFKGKWDKPFKPETTSEST 232

  Fly   251 FFRSKDDQSRAEFMEQTDYF--YYTTSEKLKAQILRLPYKGKNSLFVLLP---YALNGIHDLVKN 310
            |:.........:.|.|.::.  ||..  :|..::|.|.|....|:.:.:|   .....:.||...
Zfish   233 FYIDDKTTVPVQMMHQYEHLKVYYDV--ELFTKVLCLDYNDSFSMILAVPDVYMKQKTMKDLEMT 295

  Fly   311 LENDELKSAQWAMEEVKVKVTLPKFHFDYQQNLKETLRSLGVREIFEDSASLPGLTRGADVAGKV 375
            :....::..:.::.|.||.:.:||.......:||:.|:.:|:.::|.|.|...|::.     ..:
Zfish   296 VSRQHIEKWRRSVSERKVDIYVPKLSLKTSYSLKDILKGMGMTDMFSDKADFTGVSE-----ENI 355

  Fly   376 KVSNILQKAGINVNEKGTEAYAATVVEIENKFGGSTAIEEFNVNRPFVFFIEEESTGNILFAGKV 440
            .||.:|.||.::::|:||.|.|.|.|||...  ....:.:...:.||:.||.:::..||||.|||
Zfish   356 FVSKVLHKATLDIDEQGTTAAAVTGVEIRPT--SYDPLSDLKFDHPFMIFITDQTNDNILFVGKV 418

  Fly   441 HSP 443
            .:|
Zfish   419 VNP 421

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn27A	NP_001260143.1	SERPIN	72..440	CDD:238101	102/378 (27%)
serpina7	XP_021331940.1	alpha-1-antitrypsin_like	54..418	CDD:239011	102/378 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3275
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	4.010