Protein Alignment Spn27A and SERPINB5

DIOPT Version :9

• Sequence 1: NP_001260143.1
• Gene: Spn27A / 45815
• FlyBaseID: FBgn0028990
• Length: 447
• Species: Drosophila melanogaster
• Sequence 2: NP_002630.2
• Gene: SERPINB5 / 5268
• HGNCID: 8949
• Length: 375
• Species: Homo sapiens
• Alignment Length: 389
• Identity: 102/389 - (26%)
• Similarity: 185/389 - (47%)
• Gaps: 37/389 - (9%)

  Fly    72 SHDPFSWHLLKTVLQNETADKNVIISPFSVKLVLALLAEAAGAGTQTQVELANTQTDIRSQNNVR 136
            ::..|:..|.|.:.:.|... ||:.||..:...|: ||:....|     :.||....:....||:
Human     7 ANSAFAVDLFKQLCEKEPLG-NVLFSPICLSTSLS-LAQVGAKG-----DTANEIGQVLHFENVK 64

  Fly   137 E--FYRKTLNSFKKENQLHETLSVRTKLFTDSFIETQQKFTATLKHFYDSEVEALDFTNP-EAAA 198
            :  |..:|:.|...:.....:|.:..:|:.|..:....:|.::.|..|..|:|.:||.:. |...
Human    65 DVPFGFQTVTSDVNKLSSFYSLKLIKRLYVDKSLNLSTEFISSTKRPYAKELETVDFKDKLEETK 129

  Fly   199 DAINAWAANITQGRLQQLVAPDNVRSSV-MLLTNLIYFNGLWRRQF--ATTFQGSFFRSKDDQSR 260
            ..||....::|.|..:.::|.::|.... :|:.|..||.|.|.::|  :.|.:..|..:|.|...
Human   130 GQINNSIKDLTDGHFENILADNSVNDQTKILVVNAAYFVGKWMKKFSESETKECPFRVNKTDTKP 194

  Fly   261 AEFMEQTDYFYYTTSEKLKAQILRLPYKGKN-SLFVLLPYAL----NGIHDLVKNLENDELKSAQ 320
            .:.|.....|.....:.:..:|:.||::.|: |:|:|||..:    .|:..:.|.|.::.|  :|
Human   195 VQMMNMEATFCMGNIDSINCKIIELPFQNKHLSMFILLPKDVEDESTGLEKIEKQLNSESL--SQ 257

  Fly   321 W----AMEEVKVKVTLPKFHFDYQQNLKETLRSLGVREIF-EDSASLPGLTRGADVAGKVKVSNI 380
            |    .|...|||:::|||..:...:.|..|.:||::.|| ||::...|::....||    :||:
Human   258 WTNPSTMANAKVKLSIPKFKVEKMIDPKACLENLGLKHIFSEDTSDFSGMSETKGVA----LSNV 318

  Fly   381 LQKAGINVNEKGTEAYAATVVEI-ENKFGGSTAIEEFNVNRPFVFFIEEESTGNILFAGKVHSP 443
            :.|..:.:.|.|.::.......| ::|       :|.|.:.||::.|....|.||:|.||..||
Human   319 IHKVCLEITEDGGDSIEVPGARILQHK-------DELNADHPFIYIIRHNKTRNIIFFGKFCSP 375

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn27A	NP_001260143.1	SERPIN	72..440	CDD:238101	99/384 (26%)
SERPINB5	NP_002630.2	maspin_like	4..375	CDD:239012	100/387 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.930