Protein Alignment Spn27A and SERPINB2

DIOPT Version :9

• Sequence 1: NP_001260143.1
• Gene: Spn27A / 45815
• FlyBaseID: FBgn0028990
• Length: 447
• Species: Drosophila melanogaster
• Sequence 2: NP_001137290.1
• Gene: SERPINB2 / 5055
• HGNCID: 8584
• Length: 415
• Species: Homo sapiens
• Alignment Length: 422
• Identity: 114/422 - (27%)
• Similarity: 191/422 - (45%)
• Gaps: 71/422 - (16%)

  Fly    76 FSWHLLKTVLQNETADKNVIISPFSVKLVLALLAEAAGAGTQTQVEL--------ANTQTDIRSQ 132
            |:.:|.|. |...:..:|:.:||:|:...:|::...:...|:.|:..        ||..|.:..:
Human    11 FALNLFKH-LAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQFNEVGANAVTPMTPE 74

  Fly   133 N--------------------------NVREFYRKTLNSFKKE--NQLHETLSVRTKLFTDSFIE 169
            |                          .:...:|...::....  |.|.|:::   |||.:....
Human    75 NFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGNYLLESVN---KLFGEKSAS 136

  Fly   170 TQQKFTATLKHFYDSEVEALDFTN-PEAAADAINAWAANITQGRLQQLVAPDNVRSSV-MLLTNL 232
            .::::....:.:|.||.:|:||.. .|.|...||:|....|:|::..|:...:|.... |:|.|.
Human   137 FREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGKIPNLLPEGSVDGDTRMVLVNA 201

  Fly   233 IYFNGLWRRQFATTFQGSF-FRSKDDQSRAEFM----EQTDYFYYTTSEKLKAQILRLPYKGKNS 292
            :||.|.|:..|.....|.: ||....|.....|    |:.:..|.   |.||||||.|||.|..|
Human   202 VYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREKLNIGYI---EDLKAQILELPYAGDVS 263

  Fly   293 LFVLLPYAL----NGIHDLVKNLENDELKSAQWA----MEEVKVKVTLPKFHFDYQQNLKETLRS 349
            :|:|||..:    .|:..|...:..|:|.  :|.    |.|.:|:|.:|:|..:....|:..|||
Human   264 MFLLLPDEIADVSTGLELLESEITYDKLN--KWTSKDKMAEDEVEVYIPQFKLEEHYELRSILRS 326

  Fly   350 LGVREIF-EDSASLPGLTRGADVAGKVKVSNILQKAGINVNEKGTEAYAAT--VVEIENKFGGST 411
            :|:.:.| :..|:..|::...|:.    :|.:..:|.::|||:||||.|.|  |:......||
Human   327 MGMEDAFNKGRANFSGMSERNDLF----LSEVFHQAMVDVNEEGTEAAAGTGGVMTGRTGHGG-- 385

  Fly   412 AIEEFNVNRPFVFFIEEESTGNILFAGKVHSP 443
              .:|..:.||:|.|..:.|..|||.|:..||
Human   386 --PQFVADHPFLFLIMHKITNCILFFGRFSSP 415

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn27A	NP_001260143.1	SERPIN	72..440	CDD:238101	112/417 (27%)
SERPINB2	NP_001137290.1	PAI-2	4..415	CDD:239013	112/420 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.930