DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn27A and serpinb1l1

DIOPT Version :9

Sequence 1:	NP_001260143.1	Gene:	Spn27A / 45815	FlyBaseID:	FBgn0028990	Length:	447	Species:	Drosophila melanogaster
Sequence 2:	NP_001009892.2	Gene:	serpinb1l1 / 494155	ZFINID:	ZDB-GENE-040715-5	Length:	384	Species:	Danio rerio

Alignment Length:	400	Identity:	118/400 - (29%)
Similarity:	195/400 - (48%)	Gaps:	46/400 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 SDSHDPFSWHLLKTVLQNETADKNVIISPFSVKLVLALLAEAAGAGTQTQVELA---NTQTDIRS 131
            |.::..||.:|.|.: ....|..||..||.|:...||:::..|...|..|:...   |:|.. :.
Zfish     5 SAANTQFSLNLFKKI-SGGNASGNVFYSPVSISSALAMVSLGAKGNTADQMFKVLGFNSQAH-QP 67

  Fly   132 QNNVREFYRKTLNSFKKENQLHETLSVRTKLFTDSFIETQQKFTATLKHFYDSEVEALDFTN-PE 195
            ...:...::|.::...|....: .||:..:|:.:...:..:||....|.:||:.:|.:||.| .|
Zfish    68 VEQIHSNFKKFMSELNKPEAPY-VLSLANRLYGEQTYQLIEKFLNDTKRYYDAGLEKVDFINKSE 131

  Fly   196 AAADAINAWAANITQGRLQQLVAPDNVRSSV-MLLTNLIYFNGLWRRQF--ATTFQGSFFRSKDD 257
            .|...||.|....||.:::.|:....:.:.. ::|.|.|||.|.|..:|  ..|..|.|..:|:.
Zfish   132 DARVNINTWVEKNTQEKIKDLLPSGAIDAMTRLVLVNAIYFKGNWEEKFPKEATRDGVFRLNKNQ 196

  Fly   258 QSRAEFMEQTDYFYYTTSEKLKAQILRLPYKGKN-SLFVLLPYAL----NGIHDLVKNLENDELK 317
            ....:.|.|...|.....|::|:.:|.|||.||| |:.::||..:    .|:..|.:.|..::|
Zfish   197 TKPVKMMHQKAEFPSGYIEEMKSHVLELPYAGKNLSMLIILPDEIEDETTGLQKLERALTYEKL- 260

  Fly   318 SAQWAMEEV----KVKVTLPKFHFDYQQNLKETLRSLGVREIFE-DSASLPGLTRGADVAGKVKV 377
             .:|...||    :|:|:||||..:...::|..|.|:|:.::|: ...:|.|::...|:.    :
Zfish   261 -MEWTKPEVMHQREVQVSLPKFKTEQTYDMKSLLVSMGMEDVFDPQKVNLTGMSSSNDLV----L 320

  Fly   378 SNILQKAGINVNEKGTEAYAATVVEIENKFGGSTAIEE---------FNVNRPFVFFIEEESTGN 433
            |..:.||.:.|||:||||.|||           .|||:         ||.:.||:|||....|.:
Zfish   321 SKAIHKAFVEVNEEGTEAAAAT-----------AAIEKLMCYIPPLSFNADHPFLFFIRHNPTKS 374

  Fly   434 ILFAGKVHSP 443
            |||.|::.||
Zfish   375 ILFYGRLCSP 384

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn27A	NP_001260143.1	SERPIN	72..440	CDD:238101	115/393 (29%)
serpinb1l1	NP_001009892.2	PAI-2	4..384	CDD:239013	116/398 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BBFJ
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920