DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn27A and Spn77Ba

DIOPT Version :9

Sequence 1:	NP_001260143.1	Gene:	Spn27A / 45815	FlyBaseID:	FBgn0028990	Length:	447	Species:	Drosophila melanogaster
Sequence 2:	NP_001287128.1	Gene:	Spn77Ba / 40234	FlyBaseID:	FBgn0262057	Length:	450	Species:	Drosophila melanogaster

Alignment Length:	463	Identity:	121/463 - (26%)
Similarity:	222/463 - (47%)	Gaps:	54/463 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LAVMLLSLFLSALATGN---------GNSIPTTTTPQGVFETRTDKLPGGAASVPSGAGIYDDID 63
            :.::|.::||.:....|         ||.:...|.|. .|::       |.:.:.|....: |.|
  Fly    12 IPLLLGAIFLCSADPQNNQAPLQLSVGNPLTAFTAPT-AFQS-------GVSHIQSMRSNF-DTD 67

  Fly    64 TFVPFRSDSHDPFSWHLLKTV-LQNETADKNVIISPFSVKLVLALLAEAAGAGTQTQVELANTQT 127
            ..|.......| |:..||:.: ::.|.|:|:.:||||||..:|.||.|.:...|:.|:: .:.:.
  Fly    68 VLVSISQGVQD-FALDLLQRISVEVEKANKDFMISPFSVWSLLVLLYEGSEGETRNQLK-KSLRI 130

  Fly   128 DIRSQNNVREFYRKTLNSFKKENQLHETLSVRT--KLFTDSFIETQQKFTATLKHFYDSEVEALD 190
            ::..: .:|..| |..:||.  |....|:.|.|  .::|......:..:...::: |:.:...:|
  Fly   131 NVEDE-KLRGAY-KVWSSFL--NITTSTIEVATLQAIYTGKGYPIKNNYRDAIQN-YNVQPMEVD 190

  Fly   191 FTNPEAAADAINAWAANITQGRLQQLVAPDNVRSSVMLLTNLIYFNGLWRRQFATTF---QGSFF 252
            |.:|::... ||......|:|.:...:.|.:|..:.|.|.:.:||.|.|:..|..|.   :..|.
  Fly   191 FYSPDSVIQ-INEDTNRTTRGLIPYTILPQDVYGAKMFLLSSLYFKGQWKFPFNKTLTREEPFFS 254

  Fly   253 RSKDDQSRAEFM-EQTDYFYYTTSEKLKAQILRLPY--KGKNSLFVLLPYALNGIHDLVKNLEND 314
            .|.:...:...| ::.::.|.:..|.|...:|.|||  :.:.::.|:||.....::|:..||:..
  Fly   255 ESGEVIGKIPMMVQEANFAYVSNVEGLDGYVLELPYGTQDRLAMIVVLPKRGFKLNDVANNLKAL 319

  Fly   315 ELKS--------AQWAMEEVKVKVTLPKFHFDYQQNLKETLRSLGVREIF-EDSASLPGLTRGAD 370
            .|:.        ...|.|:.:|:|.:|||.......||..|..:|:|::| |::|:|..::.|
  Fly   320 GLRPILQRLAAFRNRASEDNEVEVMMPKFVTATDFTLKGVLIQMGIRDLFDENTANLDRMSSG-- 382

  Fly   371 VAGKVKVSNILQKAGINVNEKGTEAYAATVVEIENKFGGSTAIEEFNVNRPFVFFIEEESTGNIL 435
            :..|:    ::....|.|:|:||.|.|.|...:.||    ....:|.:||||.:.|.|::||.:|
  Fly   383 LFAKL----VVHSTKIIVDEQGTTAGAVTEAALANK----ATPPKFLLNRPFQYMIVEKATGLLL 439

  Fly   436 FAGKVHSP 443
            |||:|.:|
  Fly   440 FAGQVRNP 447

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn27A	NP_001260143.1	SERPIN	72..440	CDD:238101	105/385 (27%)
Spn77Ba	NP_001287128.1	SERPIN	75..444	CDD:238101	105/386 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	3.020