DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn27A and agt

DIOPT Version :9

Sequence 1:	NP_001260143.1	Gene:	Spn27A / 45815	FlyBaseID:	FBgn0028990	Length:	447	Species:	Drosophila melanogaster
Sequence 2:	NP_932329.1	Gene:	agt / 322485	ZFINID:	ZDB-GENE-030131-1205	Length:	454	Species:	Danio rerio

Alignment Length:	483	Identity:	100/483 - (20%)
Similarity:	183/483 - (37%)	Gaps:	76/483 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LAVMLLSLFLSALATGNGNSIPTTTTPQGVFETRT--------------------DKLPGGAASV 52
            :.:.|..||||..|....|.:  ...|..:|.:..                    ..|||.....
Zfish     1 MKMFLAFLFLSCFAMARTNRV--YVHPFNLFSSENISCEVIQSEEHKPLETVHPLPPLPGSTDPD 63

  Fly    53 PSGAGIYDDIDTF---VPFRSDSHDPFSWHLLKTVLQNETADKNVIISPFSVKLVLALLAEAAGA 114
            |..|...:.:...   ....::..:.....:.:| |.......|.::||.:.  ..||:....||
Zfish    64 PRTASAAESLKNLTQRTAVLAELQNSLGLRMYQT-LSRTQKHTNTLLSPLNA--FGALVTLYLGA 125

  Fly   115 GTQTQV--------ELANTQTD----IRSQNNVREFYRKTLNSFKKE-NQLHETLSVRTKLFTDS 166
            ..:|.:        .|.:.|||    :.....:|     ||.:.... ::..:.|......|.:|
Zfish   126 SKKTAISYQQLLGLNLESEQTDCAYFVDGHTVLR-----TLQAISAHVDESRKELRTLVWTFVNS 185

  Fly   167 FIETQQKFTATLKHFY-DSEVEALDFTNPEAAADAINAWAANITQGRLQQL---VAPDNVRSSVM 227
            ..:..::|....:.|. ||.|.::||:..:.|...:|.:....:..:::.:   |.|    .:.:
Zfish   186 DADLSKEFLRGTQDFSDDSFVRSVDFSQAKDAEVEVNNFIQKTSDNKVKSMFKGVTP----KTDL 246

  Fly   228 LLTNLIYFNGLWRRQF---ATTFQGSFFRSKDDQSRAEFMEQTDYFYYTTSEKLKAQILRLPYKG 289
            |..:.::|.|.|:..|   ||:.| .|:..|:...:..||..|..:.|......|..|:||....
Zfish   247 LFASSVHFKGNWKTAFQPEATSDQ-DFWTQKNSSVQVPFMMHTGDYKYLDDAGRKCSIVRLGLSK 310

  Fly   290 KNSLFVLLPYALNGIHDLVKNLENDELKSAQWA--MEEVKVKVTLPKFHFDYQQNLKETLRSLGV 352
            :..:.::||:....:.|:.|.|..   ....|.  ::|..::::||||......:|:..|..:.|
Zfish   311 RTFMLLVLPHEGASLQDIEKPLLT---VIPTWLRHLKEKYLELSLPKFSLTAVTDLRSVLSEMAV 372

  Fly   353 RE-IFEDSASLPGLTRGADVAGKVKVSNILQKAGINVNEKGTEAYAATVVEIENKFGGSTAIEEF 416
            .: :....||.    |.........|..:|.|....:.|.|:        |::|:.....|..:.
Zfish   373 EKYLMGSDASF----RRMSSKENFTVDKVLNKVVFEMTEGGS--------EVQNRTDDGRAPHKV 425

  Fly   417 NVNRPFVFFIEEESTGNILFAGKVHSPT 444
            ..||||.|.:.|.::..||..||:.:||
Zfish   426 TFNRPFFFAVVEGNSNAILMLGKIINPT 453

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn27A	NP_001260143.1	SERPIN	72..440	CDD:238101	83/390 (21%)
agt	NP_932329.1	angiotensinogen	82..452	CDD:239009	84/397 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910