DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn27A and Serpina4

DIOPT Version :9

Sequence 1:	NP_001260143.1	Gene:	Spn27A / 45815	FlyBaseID:	FBgn0028990	Length:	447	Species:	Drosophila melanogaster
Sequence 2:	NP_659565.2	Gene:	Serpina4 / 246328	RGDID:	708581	Length:	423	Species:	Rattus norvegicus

Alignment Length:	389	Identity:	106/389 - (27%)
Similarity:	187/389 - (48%)	Gaps:	48/389 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    78 WHLLKTVLQNETADKNVIISPFSVKLVLALLAEAAGAGTQTQV--ELANTQTDIRSQNNVREFYR 140
            :||    :.::.::||:..||.|:.:.||:|:..||..||.|:  .|....|.: |...:.|.:|
  Rat    60 YHL----IASQNSEKNIFFSPLSISVSLAILSTGAGGDTQAQILEGLGFNLTKL-SLPEIHEGFR 119

  Fly   141 KTLNSFKK---ENQLHETLSVRTKLFTDSFIETQQKFTATLKHFYDSEVEALDFTNPEAAADAIN 202
            ...::..:   |.|    :||.:.|.....::...:|.:.::..|:|:|...:|.:.|||...||
  Rat   120 SLQHTIARPFTEPQ----ISVGSALILSQNLQILSEFVSAIETSYNSKVLHANFRDKEAAVQLIN 180

  Fly   203 AWAANITQGRLQQLV---APDNVRSSVMLLTNLIYFNGLWRRQFATT--FQGSFFRSKDDQSRAE 262
            .:....|||:::.||   :|| |:   |:|.|.|:|.|||::.|.::  ....|:..::...:..
  Rat   181 NYVKQNTQGKIKNLVSDLSPD-VK---MVLVNYIFFQGLWKKPFPSSRVSTSDFYVDENTVVKIP 241

  Fly   263 FM--EQTDYFYYTTSEKLKAQILRLPYKGKNSLFVLLPYALNGIHDLVKNLENDELKS----AQW 321
            .|  ::.|: :|....::...:||:.|:|....|.:||       |..|..|.:::.|    .:|
  Rat   242 MMLQDKEDH-WYLEDRRVPCTVLRMDYRGDAVAFFILP-------DQGKMNEVEQVLSPGMLLRW 298

  Fly   322 ------AMEEVKVKVTLPKFHFDYQQNLKETLRSLGVREIFEDSASLPGLTRGADVAGKVKVSNI 380
                  .....|:.:.||||.......|.|.|..||.:::|..:|:...:::    ..|:.:|.:
  Rat   299 KRLLQNRFFYRKLILQLPKFSISNSYELDEILPDLGFQDLFTPNANFSNISK----KEKLYLSKV 359

  Fly   381 LQKAGINVNEKGTEAYAATVVEIENKFGGSTAIEEFNVNRPFVFFIEEESTGNILFAGKVHSPT 444
            ..|..::|||.||:|.||| ......|...........||||:..:...|:.:|||.|||.:||
  Rat   360 FHKTVLDVNEVGTKAAAAT-GSFATFFSAQPKKRYLIFNRPFLVILYSTSSQDILFMGKVVNPT 422

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn27A	NP_001260143.1	SERPIN	72..440	CDD:238101	102/383 (27%)
Serpina4	NP_659565.2	SERPIN	52..418	CDD:294093	102/383 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.110