DRSC/TRiP Functional Genomics Resources

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Protein Alignment Spn27A and Serpina3g

DIOPT Version :9

Sequence 1:NP_001260143.1 Gene:Spn27A / 45815 FlyBaseID:FBgn0028990 Length:447 Species:Drosophila melanogaster
Sequence 2:NP_033277.2 Gene:Serpina3g / 20715 MGIID:105046 Length:440 Species:Mus musculus


Alignment Length:400 Identity:118/400 - (29%)
Similarity:195/400 - (48%) Gaps:42/400 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly    62 IDTFVPFRSDSHDPFSWHLLKTVLQNETADKNVIISPFSVKLVLALLAEAAGAGTQTQVELAN-- 124
            :|:.....|::...||.: .|.||:|  .|:||:.||||:...||||  :.||.:.|..|:..  
Mouse    32 VDSLTLVSSNTDFAFSLY-RKLVLKN--PDENVVFSPFSICTALALL--SLGAKSNTLKEILEGL 91

  Fly   125 ----TQTDIRSQNNVREFYRKTLNSFKKE-NQLHETLSVRTKLFTDSFIETQQKFTATLKHFYDS 184
                |:|   .:.::.:.:|..|:...:. ||:.  :|..:.||.:..::...:|....:..|.:
Mouse    92 KFNLTET---PEPDIHQGFRYLLDLLSQPGNQVQ--ISTGSALFIEKHLQILAEFKEKARALYQA 151

  Fly   185 EVEALDFTNPEAAADAINAWAANITQGRLQQLVAPDNVRSSVMLLTNLIYFNGLWRRQF--ATTF 247
            |....||..|..|...||.:.:|.|||:::||:: ....|.:|:|.|.|||.|.|:..|  ..||
Mouse   152 EAFTADFQQPLKATKLINDYVSNHTQGKIKQLIS-GLKESMLMVLVNYIYFKGKWKNPFDPNDTF 215

  Fly   248 QGSFFRSKDDQSRAEFMEQTDYFYYTT----SEKLKAQILRLPYKGKNSLFVLLPYALNGIHDLV 308
            :..|:.   |:.|:..:......|.||    .|:|...::.|.|.|..|...:|| ....:..:.
Mouse   216 KSEFYL---DEKRSVIVSMMKTGYLTTPYFRDEELSCTVVELKYTGNASAMFILP-DQGRMQQVE 276

  Fly   309 KNLENDELKSAQWAMEEVKV-KVTLPKFHFDYQQNLKETLRSLGVREIFEDSASLPGLTRGADVA 372
            .:|:.:.|:..:.:::...: ::.||||......:|:..|..||:||:|...|.|..:|...|  
Mouse   277 ASLQPETLRKWKNSLKPRMIHELRLPKFSISTDYSLEHILPELGIREVFSTQADLSAITGTKD-- 339

  Fly   373 GKVKVSNILQKAGINVNEKGTEAYAATVVEIENKFG-GSTAIEEF---NVNRPFVFFIEEESTGN 433
              ::||.::.||.::|.||||||.|||     ...| |..|:.:|   ..||||:..|.:.....
Mouse   340 --LRVSQVVHKAVLDVAEKGTEAAAAT-----GMAGVGCCAVFDFLEIFFNRPFLMIISDTKAHI 397

  Fly   434 ILFAGKVHSP 443
            .||..||.:|
Mouse   398 ALFMAKVTNP 407

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Spn27ANP_001260143.1 SERPIN 72..440 CDD:238101 113/385 (29%)
Serpina3gNP_033277.2 SERPIN 46..407 CDD:214513 115/384 (30%)
RCL 357..382 11/29 (38%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D556621at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR11461
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
33.020

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