Protein Alignment Spn27A and Serpina1a

DIOPT Version :9

• Sequence 1: NP_001260143.1
• Gene: Spn27A / 45815
• FlyBaseID: FBgn0028990
• Length: 447
• Species: Drosophila melanogaster
• Sequence 2: NP_001239498.1
• Gene: Serpina1a / 20700
• MGIID: 891971
• Length: 436
• Species: Mus musculus
• Alignment Length: 457
• Identity: 121/457 - (26%)
• Similarity: 198/457 - (43%)
• Gaps: 60/457 - (13%)

  Fly    17 LSALATGNGNSIPTTTTPQ---GVFETRTDKLPGGAASVPSGAGIYDDI---DTFVPFRSDSHDP 75
            ||.|.|..|.......||.   |:.     .|.|....|||  .:.:|:   ||....:|.:...
Mouse     9 LSRLFTVKGQKARWKMTPSISWGLL-----LLAGLCCLVPS--FLAEDVQETDTSQKDQSPASHE 66

  Fly    76 FSWHL------LKTVLQNETADKNVIISPFSVKLVLALLAEAAGAGTQTQV----ELANTQTDIR 130
            .:.:|      |...|.:::...|:..||.|:....|:|:..:...|.||:    :...|||
Mouse    67 IATNLGDFAISLYRELVHQSNTSNIFFSPVSIATAFAMLSLGSKGDTHTQILEGLQFNLTQT--- 128

  Fly   131 SQNNVREFYR---KTLNSFKKENQLHETLSVRTKLFTDSFIETQQKFTATLKHFYDSEVEALDFT 192
            |:.::.:.::   :|||....|.|    ||....||.::.::..:||....|:.|.:||.:::|.
Mouse   129 SEADIHKSFQHLLQTLNRPDSELQ----LSTGNGLFVNNDLKLVEKFLEEAKNHYQAEVFSVNFA 189

  Fly   193 NPEAAADAINAWAANITQGRLQQLVAPDNVRSSVMLLTNLIYFNGLWRRQF--ATTFQGSFFRSK 255
            ..|.|...||.:....|||::.:.|...: :.:|..|.|.|.|.|.|::.|  ..|.:..|...:
Mouse   190 ESEEAKKVINDFVEKGTQGKIAEAVKKLD-QDTVFALANYILFKGKWKKPFDPENTEEAEFHVDE 253

  Fly   256 DDQSRAEFMEQTDYFYYTTSEKLKAQILRLPYKGKNSLFVLLPYALNGIH-------DLV-KNLE 312
            ....:...|..:...:......|.:.:|.:.|.|..:...|||......|       :|: |.|.
Mouse   254 STTVKVPMMTLSGMLHVHHCSTLSSWVLLMDYAGNATAVFLLPDDGKMQHLEQTLSKELISKFLL 318

  Fly   313 NDELKSAQWAMEEVKVKVTLPKFHFDYQQNLKETLRSLGVREIFEDSASLPGLTRGADVAGKVKV 377
            |...:.||         :..|:.....:.|||..:..||:..||.:.|.|.|:|   :....:|:
Mouse   319 NRRRRLAQ---------IHFPRLSISGEYNLKTLMSPLGITRIFNNGADLSGIT---EENAPLKL 371

  Fly   378 SNILQKAGINVNEKGTEAYAATVVEIENKFGGSTAIEEFNVNRPFVFFIEEESTGNILFAGKVHS 442
            |..:.||.:.::|.||||.|.||:::...  ....|..|  :.||:|.|.||.|.:.:|.|||..
Mouse   372 SQAVHKAVLTIDETGTEAAAVTVLQMVPM--SMPPILRF--DHPFLFIIFEEHTQSPIFLGKVVD 432

  Fly   443 PT 444
            ||
Mouse   433 PT 434

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn27A	NP_001260143.1	SERPIN	72..440	CDD:238101	100/390 (26%)
Serpina1a	NP_001239498.1	SERPIN	76..433	CDD:214513	101/380 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010