Protein Alignment Spn27A and SRPN5

DIOPT Version :9

• Sequence 1: NP_001260143.1
• Gene: Spn27A / 45815
• FlyBaseID: FBgn0028990
• Length: 447
• Species: Drosophila melanogaster
• Sequence 2: XP_319998.2
• Gene: SRPN5 / 1280179
• VectorBaseID: AGAP009221
• Length: 482
• Species: Anopheles gambiae
• Alignment Length: 492
• Identity: 114/492 - (23%)
• Similarity: 196/492 - (39%)
• Gaps: 83/492 - (16%)

  Fly    11 MLLSLFLSALATGNGNSIPTTTTPQGVFETRTDKLPGGAASVPSGAGIYDDIDTFVPFRSDSHDP 75
            :||.|.|.....|...:.|......|:.:..:::|.|....:....|:       :..|..|
Mosquito    16 LLLPLGLLLCVCGGALAEPAAQNTSGLSKAVSEQLVGAINDLARTLGV-------MAGRGGS--- 70

  Fly    76 FSWHLLKTVLQNETADKNVIISPFSVKLVLALLAEAAGAGTQTQV--ELANTQTDIRSQNNVREF 138
                       :..:.|..:.||.|:..::.||..||...|:.::  .|...|.......|:.:.
Mosquito    71 -----------SSNSSKTELFSPVSIGSMMLLLLRAANRDTRHELLGVLRLEQYRKPGSGNIPKN 124

  Fly   139 YRKTLNSFKK----------------------------------ENQLHE-----TLSVRTKLFT 164
            |.:.|..|.:                                  :..|.|     .:.:...:|.
Mosquito   125 YARLLKEFTRDIGGKGILKQLPGWHAGGNCYPPSEGLEDEEYDDDQYLEEPIEPNVVQLANGMFL 189

  Fly   165 DSFIETQQKFTATLKHFYDSEVEALDF-TNPEAAADAINAWAANITQGRLQQLVAPDNVRSSVML 228
            ...:.....|....:..|.:::|.::| ..|:.|.:.||.|....|:||:.:::..|....:.|:
Mosquito   190 QQGLINSSNFVRLARDLYQAQIEQVNFKERPDLARNTINRWVNESTRGRIGEILLDDPDPGTQMI 254

  Fly   229 LTNLIYFNGLWRRQF---ATTFQGSFFRSKDDQSR--AEFMEQTDYFYYTTSEKLKAQILRLPYK 288
            :.|.:||.|.|...|   ..|....||...:||..  ...|..:..|.|.:|.:|:|:|:..||:
Mosquito   255 VANALYFRGTWETFFNEPQFTRPQPFFPDGEDQPSILVPTMFASGCFPYYSSPELQARIMAFPYR 319

  Fly   289 GK-NSLFVLLPYALN--GIHDLVKNLENDELKSAQWAMEEVKVKVTLPKFHFDYQQNLKETLRSL 350
            .: .|::::||...|  .:..|..:|.:.||......|:..|..|..|:.|.....:||..|:.|
Mosquito   320 NRTTSMYIVLPNDSNRARLRQLQASLSSAELDRLIGQMKMHKAIVQFPRMHASNTYDLKAALQQL 384

  Fly   351 GVREIFEDSA------SLPGLTRGADVAGKVK--VSNILQKAGINVNEKGTEAYAATVVEIENKF 407
            |||::|:.::      |......||:...|||  ||.::.|..:.:||:|||..|.|:..:|.
Mosquito   385 GVRKLFDRTSNNLKIVSGKSSANGAEARAKVKLYVSEMVHKIDLEINERGTEGGAVTITAMER-- 447

  Fly   408 GGSTAIEEFNVNRPFVFFIEEESTGNILFAGKVHSPT 444
              |.....|.|..||:..|..:.|..:||.|.|..|:
Mosquito   448 --SLPPVNFRVRGPFLIAIRHDPTKMLLFYGAVFDPS 482

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn27A	NP_001260143.1	SERPIN	72..440	CDD:238101	101/425 (24%)
SRPN5	XP_319998.2	SERPIN	76..478	CDD:238101	100/405 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920