Protein Alignment GlnRS and Qars1

DIOPT Version :10

• Sequence 1: NP_524841.1
• Gene: GlnRS / 45786
• FlyBaseID: FBgn0027090
• Length: 778
• Species: Drosophila melanogaster
• Sequence 2: NP_001007625.1
• Gene: Qars1 / 290868
• RGDID: 1359448
• Length: 775
• Species: Rattus norvegicus
• Alignment Length: 788
• Identity: 452/788 - (57%)
• Similarity: 565/788 - (71%)
• Gaps: 25/788 - (3%)

  Fly     1 MAGDDLIAKFQALGMSEQKAKETLKNANVTKNLQLSLAAA----GSATLSDGTGMLIYHMATKLK 61
            ||..|.:|.|..||:||.||:||||||.::..|:.:...|    || |:...||.|:|.:|::|:
  Rat     1 MATPDSLALFTGLGLSENKARETLKNAALSTQLREAATQAQQTLGS-TIDKATGTLLYGLASRLR 64

  Fly    62 PQTADHLPLLVRYIVEHKLDNTQRVDAALEYLLKCGQSLNANIDLQALEKECGVGVVVTPEQIER 126
              ....|..||.||...|:....::.|||||:.  ...|:. ||.:..|:||||||||||||||.
  Rat    65 --DTRRLSFLVGYIANKKIHTELQLSAALEYVR--SHPLDP-IDTKDFEQECGVGVVVTPEQIEE 124

  Fly   127 TVQAKIKASYKEALLEQRYHFNSFKILQDVRGELKWADAKSVKAAIDVEIFDLLGPKTEADLKPQ 191
            .|:|.|. .::..||.:||.|:...::.:.|..|:|||.|.:|..:|:::..|||||.||||:
  Rat   125 AVEATIN-RHRPQLLVERYRFSMGLLMGEARAALRWADGKMIKNEVDMQVLHLLGPKMEADLE-- 186

  Fly   192 TKANDKPKAAKPKAEVT------PAAQTAEAASDGATTISELMKTKVHFHAPGENFKADGYVVTE 250
                .|||.||.:.|.|      ...:..|.|....:.:.:|....:.||.||||:|..|||.|.
  Rat   187 ----KKPKVAKARLEETDRKTAKDVVENGEVAGQTLSLMEQLRGEALKFHKPGENYKTPGYVTTP 247

  Fly   251 HTERLLKEHLARTGGKVHTRFPPEPNGILHIGHAKAININFGYAAAHDGVCYLRYDDTNPEKEEE 315
            ||..|||:||..|||:|.||||||||||||||||||||.|||||.|::|:|:||:|||||||||.
  Rat   248 HTMDLLKQHLEITGGQVRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFLRFDDTNPEKEEA 312

  Fly   316 KFFLAIKEMVEWLGYKPFKITYSSDNFQQLYEWAVVLINKGLAYVCHQKAEELKGFNPKPSPWRE 380
            |||.||.:||.||||.|:|:||:||.|.|||.|||.||.:|.||||||:.|||||.||.|||||:
  Rat   313 KFFTAIYDMVTWLGYTPYKVTYASDYFDQLYAWAVELIRRGQAYVCHQRGEELKGHNPLPSPWRD 377

  Fly   381 RPIEESLRLFEDMKRGKIDEGAATLRMKVTLEEGKMDPVAYRIKFISHHRTGSDWCIYPTYDYTH 445
            |||||||.|||.|::||..||.||||||:.:|:|||||||||:|:..|||||..|||||||||||
  Rat   378 RPIEESLLLFEAMRKGKFAEGEATLRMKLVMEDGKMDPVAYRVKYTPHHRTGDKWCIYPTYDYTH 442

  Fly   446 CLCDSLEDITHSLCTKEFQSRRSSYYWLCNALGIYCPVQWEYGRLNMNYALVSKRKIAKLITEQI 510
            |||||:|.|||||||||||:|||||:||||||.:||||||||||||::||:||||||.:|:....
  Rat   443 CLCDSIEHITHSLCTKEFQARRSSYFWLCNALDVYCPVQWEYGRLNLHYAVVSKRKILQLVAAGA 507

  Fly   511 VHDWDDPRLFTLTALRRRGFPAEAINNFCAQMGVTGAQIAVDPAMLEAAVRDVLNVTAPRRLVVL 575
            |.|||||||||||||||||||.||||||||::|||.||..::|.:|||.||||||.||||.:.||
  Rat   508 VRDWDDPRLFTLTALRRRGFPPEAINNFCARVGVTVAQTTMEPHLLEACVRDVLNDTAPRAMAVL 572

  Fly   576 EPLKVTIKNFPHAAPVQLEVPDFPQNPQQGTHKITLDKVIYIEQGDFKLEPEKGYRRLAPKQSVG 640
            |||:|.|.|||...|:.:.||:||.:..:|.|::.....::||:.|||.|.|.||:|||..|.||
  Rat   573 EPLQVVITNFPAPKPLDIRVPNFPADETKGFHQVPFASTVFIERTDFKEESEPGYKRLAWGQPVG 637

  Fly   641 LRHAGLVISVDEIVKDPATGQVVELICTSQPAEQAEKPKAFVQWVSQPIQLEVRLYEQLFKHKNP 705
            |||.|.||.:..:|:. ::|.|..|..|.:.|:..||||||:.|||||:..|:||||:||:||||
  Rat   638 LRHTGYVIELQHVVRG-SSGCVECLEVTCRRADAGEKPKAFIHWVSQPLVCEIRLYERLFQHKNP 701

  Fly   706 EDPNEVPGGFLSDISEQSMSVVV-AFADRALNQAKVYDKFQFERIGFFSVDPDTSANHLVFNRTV 769
            |||.|||||||||::..|:.|:. |..|.::..||.:|||||||:|:||||||:....:||||||
  Rat   702 EDPVEVPGGFLSDLNPASLQVIKGALVDCSVALAKPFDKFQFERLGYFSVDPDSHQGQVVFNRTV 766

  Fly   770 GLKEDAGK 777
            .||||.||
  Rat   767 TLKEDPGK 774

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GlnRS	NP_524841.1	PLN02859	10..777	CDD:178450	446/777 (57%)
Qars1	NP_001007625.1	PLN02859	2..774	CDD:178450	449/785 (57%)