Protein Alignment GlnRS and Eprs1

DIOPT Version :10

• Sequence 1: NP_524841.1
• Gene: GlnRS / 45786
• FlyBaseID: FBgn0027090
• Length: 778
• Species: Drosophila melanogaster
• Sequence 2: NP_001416494.1
• Gene: Eprs1 / 289352
• RGDID: 1310952
• Length: 1519
• Species: Rattus norvegicus
• Alignment Length: 749
• Identity: 211/749 - (28%)
• Similarity: 321/749 - (42%)
• Gaps: 110/749 - (14%)

  Fly    56 MATKLKPQTADHLPLLVRYIVEH-KLDNTQRVDAALEYLLKCGQSLNANIDLQALEKECGVGVVV 119
            ||.......|.:.||.....||| |.|.:..|:...|.||:..:|                 ||.
  Rat     1 MAALCLTVNAGNPPLEALLAVEHVKGDVSISVEEGKENLLRVSES-----------------VVF 48

  Fly   120 TPEQIERTVQAKIKAS---YKEALLEQRY--HFNSFKILQDVRGELKWADAKSVKAAIDVEIFDL 179
            |.........|::.|:   |...|:|...  |:..|...:....::..:..|.:...:.:..:.:
  Rat    49 TDTNSILRYLARVAATSGLYGSNLMEHTEIDHWLEFSATKLSSCDVLTSAIKELNHCLSLRTYLV 113

  Fly   180 LGPKTEADLKPQTKANDKPKAAKPKAEVTPAAQTAEAASDGATTISELM---KTKVH-------- 233
            ....|.|||                        ...|...|.....|.:   ||.||
  Rat   114 GNSLTLADL------------------------CVWATLKGNAACQEHLRQSKTLVHVNRWYGFL 154

  Fly   234 -----FHAPGENFKADGYVVTEHTERLLKEHLAR-------TGGKVHTRFPPEPNGILHIGHAKA 286
                 |.:.|..:.|.....|...:|  |:.:.:       ..|||..|||||.:|.||||||||
  Rat   155 EAQQAFRSVGTKWDASANKATGAPDR--KQDIGKFVELPGAEMGKVTVRFPPEASGYLHIGHAKA 217

  Fly   287 ININFGYAAAHDGVCYLRYDDTNPEKEEEKFFLAIKEMVEWLGYKPFKITYSSDNFQQLYEWAVV 351
            ..:|..|.....|...:|:||||||||:|.|...|.|.|..|..||.:.||:||:|:.:.::|..
  Rat   218 ALLNQHYQVNFKGKLIMRFDDTNPEKEKEDFEKVILEDVAMLHIKPDQFTYTSDHFETIMKYAEK 282

  Fly   352 LINKGLAYVCHQKAEELKGFNPK--PSPWRERPIEESLRLFEDMKRGKIDEGAATLRMKVTLEEG 414
            ||.:|.|||....|:|:|....:  .|..|:.|:|::|:::|:||||.....:..||.|:.:...
  Rat   283 LIEEGKAYVDDTPADEMKAEREQRIESRHRKNPVEKNLQMWEEMKRGSQFGQSCCLRAKIDMSSN 347

  Fly   415 K---MDPVAYRIKFISHHRTGSDWCIYPTYDYTHCLCDSLEDITHSLCTKEFQSRRSSYYWLCNA 476
            .   .||..||.|...|.|||:.:.:|||||:...:.||:|.:||:|.|.|:..|...:||:..|
  Rat   348 NGCMRDPTLYRCKIQPHPRTGNKYNVYPTYDFACPIVDSIEGVTHALRTTEYHDRDEQFYWIIEA 412

  Fly   477 LGIYCPVQWEYGRLNMNYALVSKRKIAKLITEQIVHDWDDPRLFTLTALRRRGFPAEAINNFCAQ 541
            |||..|..|||.|||:|..::||||:...:.|.:|..|||||..|:..:.|||...|.:..|.|.
  Rat   413 LGIRKPYIWEYSRLNLNNTVLSKRKLTWFVNEGLVDGWDDPRFPTVRGVLRRGMTVEGLKQFIAA 477

  Fly   542 MGVTGAQIAVD-------PAMLEAAVRDVLNVTAPRRLVVLEPLKVTIKNFPHAAPVQLEVPDFP 599
            .|.:.:.:.::       ...|.|..:.|::..|||.:.:|:...:.: |...|.....||...|
  Rat   478 QGSSRSVVNMEWDKIWAFNKKLRALCKKVIDPVAPRYVALLKKEVIPV-NILDAQEEMKEVARHP 541

  Fly   600 QNPQQGTHKITLDKVIYIEQGDFKLEPEKGYRRLAPKQSVGLRHAGLVISVDEIVKDPATGQVVE 664
            :||..|...:.....::||..|.:...|        .:.|...:.| .|::.:|.|:| .|::..
  Rat   542 KNPDVGLKPVWYSPKVFIEGADAETFSE--------GEMVTFINWG-NINITKIHKNP-DGKITS 596

  Fly   665 LICTSQPAEQAEKPKAFVQWVSQ-----PIQLEVRLYEQLFKHK---NPEDPNEVPGGFLSDISE 721
            |........:..|....:.|:::     |:......||.|....   ..||       |...:::
  Rat   597 LDAKLNLENKDYKKTTKITWLAETTQALPVPAVCVTYEHLITKPVLGKDED-------FKQYVNK 654

  Fly   722 QSMSVVVAFADRALNQAKVYDKFQFERIGFFSVD 755
            .|....:...|..|...|..|..|.:|.|||..|
  Rat   655 DSKHEELMLGDPCLKDLKKGDIIQLQRRGFFICD 688

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GlnRS	NP_524841.1	PLN02859	10..777	CDD:178450	211/749 (28%)
Eprs1	NP_001416494.1	None