Protein Alignment GlnRS and ears-2

DIOPT Version :10

• Sequence 1: NP_524841.1
• Gene: GlnRS / 45786
• FlyBaseID: FBgn0027090
• Length: 778
• Species: Drosophila melanogaster
• Sequence 2: NP_499917.2
• Gene: ears-2 / 176860
• WormBaseID: WBGene00001338
• Length: 481
• Species: Caenorhabditis elegans
• Alignment Length: 504
• Identity: 110/504 - (21%)
• Similarity: 178/504 - (35%)
• Gaps: 157/504 - (31%)

  Fly   267 VHTRFPPEPNGILHIGHAKAININFGYAAAHDGVCYLRYDDTNPEKEEEKFFLAIKEMVEWLGYK 331
            |..||.|.|.|.||||..:....|:.:|..:.|...||.:||    :..:|....::.:
 Worm    11 VRVRFAPSPTGHLHIGGLRTAFFNYLFAKKYGGDFILRIEDT----DRTRFVDDAQDQI------ 65

  Fly   332 PFKITYSSDNFQQL--------------YEW----------AVVLINKGLAYVCHQKAEELKGFN 372
                 |||.||..|              ||.          |..||:.|.||.|......|
 Worm    66 -----YSSLNFYNLLPDEGPREGGKFGPYEQSKRLEIYRNAAYRLIDSGHAYRCFCSENRL---- 121

  Fly   373 PKPSPWRERPIEESLRLFEDMKRGKI---DEGAATL--RMKVTLEE-GKMDPVAYRI-------- 423
                        :.||...: |||:|   |...|.|  |..|.:|: |:...:.:::
 Worm   122 ------------DLLRKTAE-KRGEIPKYDRKCANLSSRDAVKMEQNGEKFVIRFKLDKQNVQFH 173

  Fly   424 --------KFISHHRTGSDWCI-----YPTYDYTHCLCDSLEDITHSLCTKEFQSRRSSYYWLCN 475
                    :||..    ||..:     :|||...:.:.|...:|:|.:...|:.|....:..|..
 Worm   174 DEVFGSVNQFIDE----SDPVLLKSDGFPTYHLANVIDDRKMEISHVIRGMEWLSSTGKHTILYK 234

  Fly   476 ALGIYCPVQWEYGRLNMNYALVSKRKIAKLITEQIVHDWDD-----PRLFTLTALRRRGFPAEAI 535
            |.. :.|.::.:..|.|..|   .:|::|...:..|..:.:     |.. .|..:.|.|   ..|
 Worm   235 AFN-WTPPKFVHLSLIMRSA---TKKLSKRDKDAFVSYYSEQLGALPEA-VLNLMIRNG---AGI 291

  Fly   536 NNFCAQ-------------MGVTGAQ-IAVDPAMLEAAVR----------------DVLNVTAP- 569
            .||.|:             :.:.|.: :.:|..:|:...|                |:||..:.
 Worm   292 RNFDAEHFYSLDEMIEQFDLSLLGRRNLLLDSDVLQKYSRMAFQKSDFKELYPRIIDILNKKSNY 356

  Fly   570 -------RRLVVLEPLKVTIKNFPHAAPVQLEVPDFPQNPQQG-----TH-----KITLDKVIYI 617
                   :::|..  ||...:||...:.:..|...|...||..     :|     :..|:.::.|
 Worm   357 STSREDIQKIVTF--LKAKEENFGFLSSLSTEFSWFFTRPQSSQLLKESHPNVDLRNILNSLLEI 419

  Fly   618 EQGDFKLEPEKGYRRLAPKQSVGLRHA-GLV-ISVDEIVKDPATGQVVE 664
            |.  |..|   ....||....:.|..| |:| ||:....|.|...::||
 Worm   420 EV--FNSE---SLEYLAKNHQLNLAKAMGIVRISLIGSKKGPPISELVE 463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GlnRS	NP_524841.1	PLN02859	10..777	CDD:178450	110/504 (22%)
ears-2	NP_499917.2	GlnS	8..475	CDD:439779	110/504 (22%)