Protein Alignment IleRS and LeuRS-m

DIOPT Version :10

• Sequence 1: NP_524840.2
• Gene: IleRS / 45785
• FlyBaseID: FBgn0027086
• Length: 1229
• Species: Drosophila melanogaster
• Sequence 2: NP_647932.1
• Gene: LeuRS-m / 38581
• FlyBaseID: FBgn0027085
• Length: 869
• Species: Drosophila melanogaster
• Alignment Length: 1068
• Identity: 194/1068 - (18%)
• Similarity: 317/1068 - (29%)
• Gaps: 386/1068 - (36%)

  Fly     7 RNDVCRVPENINFPAEEENVLQKWRHENIFEKCSQLSKG-------KPKYTFYDGPPFATGLPHY 64
            |||...:..::....|..     ||        .|||.|       :.||......|:.:|..|.
  Fly    28 RNDNPELTSDVKHRIEAH-----WR--------EQLSGGQFNPKDSQDKYYVLSMFPYPSGNLHM 79

  Fly    65 GHILAGTIKDIVTRYAYQQGYHVDRRFGWDCHGLPVEFEIDKLLNIKG--PEDVAKMGIAAYNAE 127
            ||:...||.|.|.|:....|.:|.:..|||..|||.|    ...|.:|  |....:..||
  Fly    80 GHVRVYTIADSVARFQRMCGKNVFQPMGWDSFGLPAE----NAANQRGVEPASWTEQNIA----- 135

  Fly   128 CRKIVMRYADEWENVVTRVGRWIDFKNDYKTLYPWYMESIWWIFKQLFDKGLVYQGVKVMPYSTA 192
                      :.:..:.|:|...|:.::..|..|.|.:....:|..|...||.||...::.:...
  Fly   136 ----------QMKEQLKRLGCSFDWNHELSTCSPKYYKWTQHLFLMLHRHGLAYQNEALVNWDPV 190

  Fly   193 CTTSLSNFEANQN----------------------------------------YKEVVD------ 211
            ..|.|::.:.:.|                                        ::::::
  Fly   191 DKTVLADEQVDANGCSWRSGAKVEKKLLRQWFIRTSAYAKQLLDGLEDPTLRDWRDIINLQRHWI 255

  Fly   212 -PCVVVALEAVSLPNTFFLVWTTTPWTLPSNFACCVHPTMTYVKVRDVKSDRLFVLAES--RLSY 273
             .|...|...::..:....||||             ||       ..:|....|::..|  .||.
  Fly   256 GECDGYAFNLLTSASGLLRVWTT-------------HP-------EHLKDPHAFLVLRSNHHLSK 300

  Fly   274 VYKSETEYEVKEKFVGKTLKDLHYKPLFPYFAKRGAEVKAYRVLVDEYVTEDSGTGIVHNAPYFG 338
            : |..........|.|.|:.                      |:..:.||....:.:...||.|.
  Fly   301 L-KGADSLSAANPFAGTTMP----------------------VVFSDEVTFPPKSDVYLAAPSFR 342

  Fly   339 EDDYRVCLAAGLITKSSEVLCPVDEAGRFTNEASDFEGQYVKDSDKQIMAALKARGNLVSSGQVK 403
            .:|..:..:.||               .||:...|.|
  Fly   343 GEDKDLWDSYGL---------------AFTSNGKDEE---------------------------- 364

  Fly   404 HSYPFCWRSDTPLIYKAVPSWFVRVEHMSKNLLDCSSQTYWVPDFVKEKRFGNWLKEARDWAISR 468
                    |.:|      .:|    |.:.|.:|..:::..     |...|..:.||   ||.|||
  Fly   365 --------SLSP------ANW----EMLRKEVLQAATRLN-----VGGYRVSSKLK---DWLISR 403

  Fly   469 NRYWGTPIPIWRSPSGDETVVIGSIKQLAELSGVQVEDLHRESIDHIEIPSAVP----------- 522
            .|||||||||                       |..:......:...::|.::|
  Fly   404 QRYWGTPIPI-----------------------VHCQKCGAVPVPEEQLPVSLPPKDSPKEAFLC 445

  Fly   523 -----GNPPLRRIAPVFDCWFESG-------SMPFAQQHFPFENEKDFMNNFPADFIAEGIDQTR 575
                 |....||.....|.:.:|.       ....:::.|.....|.||   |.|....|.:...
  Fly   446 DCPKCGEKDARRETDTMDTFVDSSWYYLRYLDAQNSERIFDTALTKKFM---PVDLYIGGKEHAV 507

  Fly   576 GWFYTLLVISTALFN------KAPFKNLIASGLVLAAD--------------------------- 607
            ...|....|:..|.:      ..||..|:..|:|:...
  Fly   508 LHLYYARFINHFLHSCGLSPTSEPFSRLLVQGMVMGRSFRVKGSGRYVPETEVEIVNAKKNQAVL 572

  Fly   608 ----------GQKMSKRKKNYPDPMEVVHKYGADALRLYLINSPVVRAESLRFKEEGVRDIIKDV 662
                      .:||||.|.|..:|.::.::||.|..|| :|.:.|.......:.......|
  Fly   573 KETKEPVVMTWEKMSKSKLNGVEPSDMFNEYGTDTTRL-IILADVAPTSHRNWSSATFPGI---- 632

  Fly   663 FLPWYNAYRFLLQNIVRYEKEDLAGNGQYTYDRERHLKNMDKASVIDVWILSFKESLLEFFATEM 727
             |.|.......||:..:..::..|.:...|.:                          ||.|.:.
  Fly   633 -LNWQKRLWLTLQDFQQAREDQTASDVVPTSE--------------------------EFLAEDA 670

  Fly   728 KMYRLYTVVPRLTKFIDQLTNWYVR---LNRRRIKGELGADQCIQSLDT---------------L 774
            |::              ...|:||:   .|.|..:....|...:|.|..               .
  Fly   671 KLF--------------DARNFYVKGATFNYRHAQQLSVAISKMQGLTNSLRRTPKHVLRHGKQF 721

  Fly   775 YDVLYTMVKMMAPFTPYLTEYIFQRLVL----FQPAG-TLEHADSVHYQMMPVSQKKFIRNDIER 834
            ...|...:.|:||..|:....::.:.|.    ..||. .|:.::.|..|..|         ||:.
  Fly   722 ERALAAQIIMLAPMAPHFASELWSKFVAIPGRLNPASQELQWSEDVLAQRWP---------DIDP 777

  Fly   835 SVALMQS---------VVELGRVMRDRRT----LPVKYPVSEIIAIHKDSQILEAIKTLQDFILS 886
            :..|..|         |:::.|...|:.|    |.:.:....:.:...|.:|......|...|.:
  Fly   778 AYNLDLSIKVNGFENCVIKVQRTHLDKVTHSDALDIAFNTESVTSYLIDKKIRTTNFVLYPGIEA 842

  Fly   887 ELNVRKLTLSSDKEKYGVTLRAEPDHKA 914
            .||: .:..:..|:|...|..||...:|
  Fly   843 ILNI-YVDKAKMKQKPPTTDDAEAQPQA 869

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
IleRS	NP_524840.2	PLN02882	9..1094	CDD:215477	192/1066 (18%)
LeuRS-m	NP_647932.1	LeuS	40..848	CDD:440261	185/1033 (18%)