Protein Alignment ThrRS and MRPL39

DIOPT Version :10

• Sequence 1: NP_723725.1
• Gene: ThrRS / 45784
• FlyBaseID: FBgn0027081
• Length: 747
• Species: Drosophila melanogaster
• Sequence 2: NP_542984.3
• Gene: MRPL39 / 54148
• HGNCID: 14027
• Length: 353
• Species: Homo sapiens
• Alignment Length: 328
• Identity: 83/328 - (25%)
• Similarity: 139/328 - (42%)
• Gaps: 73/328 - (22%)

  Fly    68 GGG--------DTRKELSPLPKYIEERNVFWEKCKAEYEAELAAKKR-EPIKVTLPDGKQVDATS 123
            |||        .:..:||| .:..|.||..:.|.||.   :|:...| |.|:|     |.|..|.
Human    19 GGGIKWRFIATSSASQLSP-TELTEMRNDLFNKEKAR---QLSLTPRTEKIEV-----KHVGKTD 74

  Fly   124 WET---------TPYEVARGISQGLADNTVISKVNGEVWDLDRVLEGNCTLQLLKF---DDPEAQ 176
            ..|         |||..|..:|:.....::::.|:|:.||:.:.|..:|.::.|.|   |..|..
Human    75 PGTVFVMNKNISTPYSCAMHLSEWYCRKSILALVDGQPWDMYKPLTKSCEIKFLTFKDCDPGEVN 139

  Fly   177 AVFWHSSAHIMGEAMERIYGGHLCYG-------PPIENGFYYDMHLEG---EGISTNDYGAMEGL 231
            ..:|.|.|.:||..:||.:.......       |.|...|.||:.|:.   |.:.|.:  .:...
Human   140 KAYWRSCAMMMGCVIERAFKDEYMVNLVRAPEVPVISGAFCYDVVLDSKLDEWMPTKE--NLRSF 202

  Fly   232 VKQ---IVKEKQNFERLEMKKSDLLEMFKYNEFKVRILNEKVTTDRTTV---YKCGSLIDLCRGP 290
            .|.   ::.:...||.||::....||:|:::::||..:.||.:.:...:   ::.|..||:..||
Human   203 TKDAHALIYKDLPFETLEVEAKVALEIFQHSKYKVDFIEEKASQNPERIVKLHRIGDFIDVSEGP 267

  Fly   291 HVRHT--------GKVKALKITKNSSTYWEGKADAETLQRVYGISFPDPKQLKE----WEKLQEE 343
            .:..|        ..|..|:.|:.|           .::|..|:|.  |..|:.    |:||.|.
Human   268 LIPRTSICFQYEVSAVHNLQPTQPS-----------LIRRFQGVSL--PVHLRAHFTIWDKLLER 319

  Fly   344 AAK 346
            :.|
Human   320 SRK 322

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ThrRS	NP_723725.1	PLN02908	79..740	CDD:178496	77/309 (25%)
MRPL39	NP_542984.3	PLN02908	44..>303	CDD:178496	69/281 (25%)