DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ThrRS and mrpl39

DIOPT Version :9

Sequence 1:	NP_001285868.1	Gene:	ThrRS / 45784	FlyBaseID:	FBgn0027081	Length:	747	Species:	Drosophila melanogaster
Sequence 2:	NP_001011362.1	Gene:	mrpl39 / 496829	XenbaseID:	XB-GENE-953160	Length:	331	Species:	Xenopus tropicalis

Alignment Length:	328	Identity:	81/328 - (24%)
Similarity:	144/328 - (43%)	Gaps:	61/328 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 AKMKKE--KKEKPSGGGDTRKELSPLPKYIEERNVFWEKCKAEYEAELAAKKREPIKVTLPDGKQ 118
            :||..|  .|||     :.:..|.|..:.||.::|               .||:...|.|.:..|
Frog    33 SKMHTELFNKEK-----ERQLSLHPRIEKIEVKHV---------------GKRDHGAVGLMNKGQ 77

  Fly   119 VDATSWETTPYEVARGISQGLADNTVISKVNGEVWDLDRVLEGNCTLQLLKFDDPEAQAV---FW 180
                   :|||..|..:|:.....:|::.|:|||||:.:.|..:|.:|.|.|.|.:.:.|   :|
Frog    78 -------STPYHCALHLSEWYCSRSVLALVDGEVWDMYKPLTKSCNIQFLTFKDEDPEEVNKAYW 135

  Fly   181 HSSAHIMGEAMERIYGGHLCYG-------PPIENGFYYDMHLEGEGISTNDYGAMEGLVKQIVKE 238
            .|.|.|:|..:|..:.......       |.|...|.||:.|:..   .:|:...|..::.:.:|
Frog   136 RSCAMILGCVLENAFKEEYMVNLIRAPEIPVISGAFCYDVVLDSR---LDDWRPTEENLRSLTRE 197

  Fly   239 KQN-------FERLEMKKSDLLEMFKYNEFKVRILNEKVTTD---RTTVYKCGSLIDLCRGPHVR 293
            ..:       ||.||:::....|:|:::.:|:.:..||.:.:   ..||::.|..:||..|||:.
Frog   198 AHSLIHKDLPFESLEVEEKVAKEIFQHSPYKLIMAEEKASQNPQGLVTVHRFGDFVDLTEGPHIP 262

  Fly   294 HTGKVKALKITKNSSTYWEGKADAETLQRVYGISFPDPKQLKE----WEKLQEEAAKRDHRKIGR 354
            .|...:..::|...|.   ....:|.::|..|:|.  |..||.    |.:|:..:.:....:..:
Frog   263 RTSFCQQYEVTAGHSL---ANIPSEHVRRFQGLSL--PWHLKAHHTVWNRLRTRSQRLVTEEHNQ 322

  Fly   355 EQE 357
            |.|
Frog   323 EPE 325

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ThrRS	NP_001285868.1	PLN02908	79..740	CDD:178496	73/303 (24%)
		TGS_ThrRS_N	109..170	CDD:133437	19/60 (32%)
		tRNA_SAD	276..323	CDD:197931	12/46 (26%)
		ThrRS_core	347..643	CDD:238394	2/11 (18%)
		ThrRS_anticodon	643..734	CDD:238437
mrpl39	NP_001011362.1	ThrS	38..>323	CDD:333237	77/319 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910