DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ThrRS and mrpl39

DIOPT Version :9

Sequence 1:	NP_001285868.1	Gene:	ThrRS / 45784	FlyBaseID:	FBgn0027081	Length:	747	Species:	Drosophila melanogaster
Sequence 2:	NP_956209.1	Gene:	mrpl39 / 334588	ZFINID:	ZDB-GENE-030131-6520	Length:	342	Species:	Danio rerio

Alignment Length:	247	Identity:	61/247 - (24%)
Similarity:	106/247 - (42%)	Gaps:	36/247 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   126 TTPYEVARGISQGLADNTVISKVNGEVWDLDRVLEGNCTLQLLKFDDPEAQAV---FWHSSAHIM 187
            :|||..||.:|:...:::.::.|:|:.|.:.:.|..:|.|.||.|.|.:.|.:   :|.|.|.::
Zfish    76 STPYSCARHLSEWHVNSSALALVDGQPWHMHKPLTRSCELTLLTFRDADPQTLNQAYWRSCAALL 140

  Fly   188 GEAMERI----YGGHLCYGP--PIENG-FYYDMHLE---------GEGISTNDYGAMEGLVKQIV 236
            |..:|..    :...|...|  |:..| |..|:.|:         .|.:.:....|:     |::
Zfish   141 GLVLESAFKDQFSVELLKTPEVPVTAGAFCCDLLLDPLLDSWKPTEENLRSLTRDAL-----QMI 200

  Fly   237 KEKQNFERLEMKKSDLLEMFKYNEFKVRILNEKVTTDR---TTVYKCGSLIDLCRGPHVRHTGKV 298
            .....:|.||:..|..||:|..:..|...:.|.....:   .|:|:||..:.|...|.|..||..
Zfish   201 SRDLPWEPLEVSASLALEIFSQSRCKQEEVEEAAAQSQNGTVTLYRCGDHVTLSSAPLVSRTGLC 265

  Fly   299 KALKITK--NSSTYWEGKADAETLQRVYGISFPDPKQLKE--WEKLQEEAAK 346
            ...::|.  ..|.:..|     ..:|..|:|.|.......  |.||::.|.:
Zfish   266 SQFEVTSIHTLSEHTRG-----VQRRAQGLSLPVNLTAHHTVWRKLRKRAER 312

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ThrRS	NP_001285868.1	PLN02908	79..740	CDD:178496	61/247 (25%)
		TGS_ThrRS_N	109..170	CDD:133437	14/43 (33%)
		tRNA_SAD	276..323	CDD:197931	12/48 (25%)
		ThrRS_core	347..643	CDD:238394	61/247 (25%)
		ThrRS_anticodon	643..734	CDD:238437
mrpl39	NP_956209.1	TGS_ThrRS_N	66..120	CDD:133437	14/43 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910