Protein Alignment ThrRS and tars-1

DIOPT Version :10

• Sequence 1: NP_723725.1
• Gene: ThrRS / 45784
• FlyBaseID: FBgn0027081
• Length: 747
• Species: Drosophila melanogaster
• Sequence 2: NP_001022033.1
• Gene: tars-1 / 174790
• WormBaseID: WBGene00006617
• Length: 725
• Species: Caenorhabditis elegans
• Alignment Length: 672
• Identity: 445/672 - (66%)
• Similarity: 545/672 - (81%)
• Gaps: 1/672 - (0%)

  Fly    75 ELSPLPKYIEERNVFWEKCKAEYEAELAAKKREPIKVTLPDGKQVDATSWETTPYEVARGISQGL 139
            :::|.|.:||||...|:|.||||:||:|||:.|||::||||||..:..:|.|||:|:|..||:||
 Worm    48 DMAPWPAFIEERIKLWDKLKAEYDAEIAAKESEPIQITLPDGKIHEGKTWRTTPFEIAERISKGL 112

  Fly   140 ADNTVISKVNGEVWDLDRVLEGNCTLQLLKFDDPEAQAVFWHSSAHIMGEAMERIYGGHLCYGPP 204
            |:..||:||||.||||||..|||..|:||||||.||:.||||||||::||||||..|||||||||
 Worm   113 AEAAVIAKVNGAVWDLDRPFEGNAKLELLKFDDDEAKQVFWHSSAHVLGEAMERYCGGHLCYGPP 177

  Fly   205 IENGFYYDMHLEGEGISTNDYGAMEGLVKQIVKEKQNFERLEMKKSDLLEMFKYNEFKVRILNEK 269
            |:.||||||..|...|..:|:..::.:||..||:||.||||||.|.|||||||||||||||:.||
 Worm   178 IQEGFYYDMWHENRTICPDDFPKIDQIVKAAVKDKQKFERLEMTKEDLLEMFKYNEFKVRIITEK 242

  Fly   270 VTTDRTTVYKCGSLIDLCRGPHVRHTGKVKALKITKNSSTYWEGKADAETLQRVYGISFPDPKQL 334
            :.|.:||||:||.||||||||||||||||||:.||||||:|||||||||:|||:|||||||.|||
 Worm   243 IHTPKTTVYRCGPLIDLCRGPHVRHTGKVKAMAITKNSSSYWEGKADAESLQRLYGISFPDSKQL 307

  Fly   335 KEWEKLQEEAAKRDHRKIGREQELFFFHELSPGSCFFQPRGAHIYNTLMGFIKAEYRKRGFQEVI 399
            |||:|||||||||||||:|:|.:|||||:|||||.|:.|:||||||.|:.||:.:||:|||.|||
 Worm   308 KEWQKLQEEAAKRDHRKLGKEHDLFFFHQLSPGSAFWYPKGAHIYNKLVDFIRKQYRRRGFTEVI 372

  Fly   400 SPNIYNAKLWMTSGHWQHYAENMFSFEAEKEKFALKPMNCPGHCLIFDNRNRSWRELPLRMADFG 464
            :||:||.|||.||||||||:|:||..|.|||:|.|||||||||||:|.:...::.|||.|.||||
 Worm   373 TPNMYNKKLWETSGHWQHYSEDMFKIEVEKEEFGLKPMNCPGHCLMFGHMPHTYNELPFRFADFG 437

  Fly   465 VLHRNELSGALTGLTRVRRFQQDDAHIFCAPEQIKSEMKGCLEFLKYVY-TIFGFSFQLVLSTRP 528
            ||||||:||||||||||||||||||||||..:||..|:|.||:||:|.| .:|||:|:|.|||||
 Worm   438 VLHRNEMSGALTGLTRVRRFQQDDAHIFCRQDQISEEIKQCLDFLEYAYEKVFGFTFKLNLSTRP 502

  Fly   529 DNYLGELEQWNDAEKALAESLNEFGMPWKENPGDGAFYGPKIDITIMDALKRAHQCATIQLDFQL 593
            :.:||.:|.|:.||..|..:||..|..|..||||||||||||||||.|||||..|||||||||||
 Worm   503 EGFLGNIETWDKAEADLTNALNASGRKWVLNPGDGAFYGPKIDITIQDALKRNFQCATIQLDFQL 567

  Fly   594 PIRFNLSYIADDGEKKRPVIIHRAILGSVERMIAILTENFAGKWPFWLSPRQVMVVPVGPAYDQY 658
            |.:|:|||..:.|||:|||:||||:|||||||.|||||::.|||||||||||..::.|..:...|
 Worm   568 PNQFDLSYFDEKGEKQRPVMIHRAVLGSVERMTAILTESYGGKWPFWLSPRQCKIITVHESVRDY 632

  Fly   659 AQSVRDQLHDAGFMSEADCDAGDTMNKKIRNAQLAQFNFILVVGDKERSSNTVNVRTRDNKVHGE 723
            |..|:.|:.:|||..|.:.:.||||||::|.|||||||||||:|.||:.:.|||||||||.|.||
 Worm   633 ANDVKKQIFEAGFEIEYEENCGDTMNKQVRKAQLAQFNFILVIGAKEKENGTVNVRTRDNAVRGE 697

  Fly   724 VSVAELITKLQKIRDEFIANED 745
            |::.:||:|.::..||::|:.:
 Worm   698 VALDKLISKFRRFADEYVADTE 719

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ThrRS	NP_723725.1	PLN02908	79..740	CDD:178496	442/661 (67%)
tars-1	NP_001022033.1	PLN02908	46..714	CDD:178496	443/665 (67%)