Protein Alignment ValRS and valS

DIOPT Version :10

• Sequence 1: NP_001260946.1
• Gene: ValRS / 45783
• FlyBaseID: FBgn0027079
• Length: 1055
• Species: Drosophila melanogaster
• Sequence 2: NP_418679.1
• Gene: valS / 948785
• ECOCYCID: EG11067
• Length: 951
• Species: Escherichia coli
• Alignment Length: 1016
• Identity: 387/1016 - (38%)
• Similarity: 556/1016 - (54%)
• Gaps: 126/1016 - (12%)

  Fly    94 YSPRYVEAQWYSWWEKEGFFTPEYGRASIDAPNPNG-----KFVMIIPPPNVTGSLHLGHALTNA 153
            |:|:.:|...|..|||:|:|            .|||     .|.::|||||||||||:|||....
E. coli     5 YNPQDIEQPLYEHWEKQGYF------------KPNGDESQESFCIMIPPPNVTGSLHMGHAFQQT 57

  Fly   154 IEDAITRYHRMKGRTTLWVPGCDHAGIATQVVVEKLLWRDEKLSRHDLGREKFIERIWDWRREKG 218
            |.|.:.||.||:|:.|||..|.||||||||:|||:.:..:|..:|||.|||.||::||:|:.|.|
E. coli    58 IMDTMIRYQRMQGKNTLWQVGTDHAGIATQMVVERKIAAEEGKTRHDYGREAFIDKIWEWKAESG 122

  Fly   219 GRIYEQLKSLGSSYDWTRVAFTMDPKLCRAVTEAFVRLHEEGSIYRSSRLVNWSCTLRSAISDIE 283
            |.|..|::.||:|.||.|..||||..|..||.|.||||::|..|||..|||||...||:||||:|
E. coli   123 GTITRQMRRLGNSVDWERERFTMDEGLSNAVKEVFVRLYKEDLIYRGKRLVNWDPKLRTAISDLE 187

  Fly   284 VDKVEIPGRTF-LSIPGYEDKVEFGVLIKFAYKVEGSDEEIIVATTRIETMLGDTAVAVHPQDDR 347
            |:..|..|..: :..|          |...|...:|.| .::|||||.||:||||.|||:|:|.|
E. coli   188 VENRESKGSMWHIRYP----------LADGAKTADGKD-YLVVATTRPETLLGDTGVAVNPEDPR 241

  Fly   348 YKHLHGKFVVHPFSTRRLPIVCDEFVDMAFGTGAVKITPAHDPNDYEVGKRCNLPFITIFNDDGY 412
            ||.|.||:|:.|...||:|||.||..||..|||.||||||||.||||||||..||.|.|...||.
E. coli   242 YKDLIGKYVILPLVNRRIPIVGDEHADMEKGTGCVKITPAHDFNDYEVGKRHALPMINILTFDGD 306

  Fly   413 I-----IGDY-------------GEFTGMKRFECRKKILEKLKALNLYRETLNNPMVVPICSRSK 459
            |     :.|.             .||..::||..||.::..:.||.|..|...:.:.||...|..
E. coli   307 IRESAQVFDTKGNESDVYSSEIPAEFQKLERFAARKAVVAAVDALGLLEEIKPHDLTVPYGDRGG 371

  Fly   460 DVVEPLIKPQWYVSCSDMAASATEAVRSGELKIIPEHHTKTWYHWMDGIRDWCVSRQLWWGHRIP 524
            .|:||::..||||....:|..|.|||.:|:::.:|:.:...::.||..|:|||:|||||||||||
E. coli   372 VVIEPMLTDQWYVRADVLAKPAVEAVENGDIQFVPKQYENMYFSWMRDIQDWCISRQLWWGHRIP 436

  Fly   525 AYHVSFTDPSLQTGSSAHGSVNDDEQYWIVARSEAEALTKAAERFGVDASKIVLKQDEDVLDTWF 589
            |::                   |:.....|.|:|.|  .:.....|.|   :||:||||||||||
E. coli   437 AWY-------------------DEAGNVYVGRNEDE--VRKENNLGAD---VVLRQDEDVLDTWF 477

  Fly   590 SSGIFPFSVFGWPDQTKDLQTFYPTSLLETGHDILFFWVARMVFFGQKLL----GK--LPFKEVY 648
            ||.::.||..|||:.|..|:.|:|||::.:|.||:|||:|||:......:    ||  :||..||
E. coli   478 SSALWTFSTLGWPENTDALRQFHPTSVMVSGFDIIFFWIARMIMMTMHFIKDENGKPQVPFHTVY 542

  Fly   649 LHPMVRDAHGRKMSKSLGNVIDPMDVIRGITLEGLHAQLVGSNLDPREIEKAKAGQKQDYPQGIP 713
            :..::||..|:|||||.||||||:|::.||:|..|..:..|:.:.|:..:|.:...::.:|.||.
E. coli   543 MTGLIRDDEGQKMSKSKGNVIDPLDMVDGISLPELLEKRTGNMMQPQLADKIRKRTEKQFPNGIE 607

  Fly   714 ECGSDALRFALCAYITQARDINLDINRVLGYRFFCNKLWNATKFALLYFTGSE-KFD-TELSASA 776
            ..|:|||||.|.|..:..||||.|:.|:.|||.||||||||::|.|:...|.: .|: .|::.|.
E. coli   608 PHGTDALRFTLAALASTGRDINWDMKRLEGYRNFCNKLWNASRFVLMNTEGQDCGFNGGEMTLSL 672

  Fly   777 AINQMDAWILSRLAAAIEACNTGFESYDFAAATSACYAFWLYDLCDVYLECLKPIFQSGSEEQQT 841
            |    |.|||:.....|:|.....:|:.|..|....|.|.....||.|||..||:...|:|.:..
E. coli   673 A----DRWILAEFNQTIKAYREALDSFRFDIAAGILYEFTWNQFCDWYLELTKPVMNGGTEAELR 733

  Fly   842 AARRTLYVCLDYGLRLLSPFMPFITEELYQRLP--RANPAPSICVASYPSNTSWRSTKIE----S 900
            ..|.||...|:..|||..|.:|||||.::||:.  ....|.:|.:..:|   .:.:::::    :
E. coli   734 GTRHTLVTVLEGLLRLAHPIIPFITETIWQRVKVLCGITADTIMLQPFP---QYDASQVDEAALA 795

  Fly   901 DVEFVQKAARIIRSARSDYNL-PNKVKTEVYIVCTDSVPSEILKR---------------YASDL 949
            |.|::::|...:|:.|::.|: |.|             |.|:|.|               :...|
E. coli   796 DTEWLKQAIVAVRNIRAEMNIAPGK-------------PLELLLRGCSADAERRVNENRGFLQTL 847

  Fly   950 ATISYCSNVVFDSPAPQGCAILTVTGQCEVHLLLKGLVEADKEIAKLQKKSDQLVQTVGKLTQAI 1014
            |.:...:.:..|...|  .::..:....|:.:.:.||:..:.|:|:|.|:..::...:.::...:
E. coli   848 ARLESITVLPADDKGP--VSVTKIIDGAELLIPMAGLINKEDELARLAKEVAKIEGEISRIENKL 910

  Fly  1015 QAADYATKVPAEVQEANETKL---CESRAEIERIAAAIETL 1052
            ....:..:.|..|......||   .|::|::....|.|..|
E. coli   911 ANEGFVARAPEAVIAKEREKLEGYAEAKAKLIEQQAVIAAL 951

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ValRS	NP_001260946.1	PTZ00419	80..1053	CDD:240411	387/1016 (38%)
valS	NP_418679.1	ValS	1..949	CDD:440291	385/1012 (38%)