Protein Alignment ValRS and ValRS-m

DIOPT Version :10

• Sequence 1: NP_001260946.1
• Gene: ValRS / 45783
• FlyBaseID: FBgn0027079
• Length: 1055
• Species: Drosophila melanogaster
• Sequence 2: NP_648268.1
• Gene: ValRS-m / 39023
• FlyBaseID: FBgn0035942
• Length: 994
• Species: Drosophila melanogaster
• Alignment Length: 1009
• Identity: 380/1009 - (37%)
• Similarity: 554/1009 - (54%)
• Gaps: 112/1009 - (11%)

  Fly    84 KDLSGALPDA--YSPRYVEAQWYSWWEKEGFFTPEYGRASIDAPNPN----GKFVMIIPPPNVTG 142
            ||.:..||.|  |.|:.||   .::||:      |:.:|::...:.:    |.:.|::|||||||
  Fly    31 KDAANELPLAAGYQPQPVE---NAYWER------EHRQANLPKASASSCKRGTYRMLLPPPNVTG 86

  Fly   143 SLHLGHALTNAIEDAITRYHRMKGRTTLWVPGCDHAGIATQVVVEKLLWRDEKLSRHDLGREKFI 207
            :|||||||...::|.|.|.....|....||||.||||||||||||:.:...:..:||:|||..|:
  Fly    87 NLHLGHALMATVQDVIARQREQLGYQVDWVPGTDHAGIATQVVVERTIAASQAKTRHELGRSAFL 151

  Fly   208 ERIWDWRREKGGRIYEQLKSLGSSYDWTRVAFTMDPKLCRAVTEAFVRLHEEGSIYRSSRLVNWS 272
            :.:|.|:.|||..|.:.|:.||...:|.|..||||.:...||..||.||.|||.|.|.:.:|||.
  Fly   152 DEVWRWKAEKGAGIVQDLRQLGCKLNWQREYFTMDEQQAHAVNVAFERLFEEGLIQRRNSVVNWC 216

  Fly   273 CTLRSAISDIEVDKVEIPGRTFLSIPGYEDKVEFGVLIKFAYKV-------EGSDEEIIVATTRI 330
            ..|||||||||||.|||.....:|:|||:.||.||.:..|||.|       :||.|||:|:|||.
  Fly   217 TALRSAISDIEVDSVEITEPVEISVPGYDHKVLFGRMYDFAYHVVDGEALPDGSVEEIVVSTTRP 281

  Fly   331 ETMLGDTAVAVHPQDDR---YKHLHGKFVVHPFSTRRLPIVCDEFVDMAFGTGAVKITPAHDPND 392
            ||:|||.||||||.|.|   |:::....:.|||....:|:|.|..||..|||||||||||||..|
  Fly   282 ETILGDVAVAVHPLDPRYAKYRNIDQVKLKHPFRDDTIPLVFDITVDQEFGTGAVKITPAHDKFD 346

  Fly   393 YEVGKRCNLPFITIFNDDGYIIGDYGEFTGMKRFECRKKILEKLKALNLYRETLNNPMVVPICSR 457
            :|:..|..|....:|.:.|.::..|.|:.|:.|||.|..|:.:|:.::|.|:..::.|.:|||||
  Fly   347 FELATRHKLEPRQVFTETGLVVDAYSEYKGIPRFEARDLIVNRLEEMDLLRQVRSHTMQLPICSR 411

  Fly   458 SKDVVEPLIKPQWYVSCSDMAASATEAVRSGELKIIPEHHTKTWYHWMDGIRDWCVSRQLWWGHR 522
            ||||:|.:|.|||::.|.|:|..|...:.||.|:|:|.:....|..|:...||||:||||||||:
  Fly   412 SKDVIEYMILPQWFLKCKDLAKDALSELHSGRLQILPPNFETEWERWLQDSRDWCISRQLWWGHQ 476

  Fly   523 IPAYHVSFTDPSLQTGSSAHGSVNDDEQYWIVARSEAEALTKAAERFGVDASKIVLKQDEDVLDT 587
            :|||.|..:..:.|               |:.|..|..|..||....|  :.:..||:|.|||||
  Fly   477 VPAYEVIDSQGNSQ---------------WVAALDEKTARQKAMRLIG--SEEFTLKRDPDVLDT 524

  Fly   588 WFSSGIFPFSVFGWPDQTKDLQTFYPTSLLETGHDILFFWVARMVFFGQKLLGKLPFKEVYLHPM 652
            ||||.:.|||..|||:::  .:..||..:::|||||:|||||||:..|.||.|:.||:.:.|:.:
  Fly   525 WFSSSLLPFSTAGWPEES--YKERYPLDIMQTGHDIIFFWVARMMMLGLKLTGEAPFQRILLNGI 587

  Fly   653 VRDAHGRKMSKSLGNVIDPMDVIRGITLEGLHAQLVGS----NLDPREIEKAKAGQKQDYPQGIP 713
            |.||||||||||:||::.|..|::|.:||.|.|.|..|    .:.|.|::.:..|..|.:|.||.
  Fly   588 VCDAHGRKMSKSIGNIVAPQQVVQGASLESLKAGLEQSCEAGIITPSELKASTIGMTQMFPNGIQ 652

  Fly   714 ECGSDALRFALCAYITQARDINLDINRVLGYRFFCNKLWNATKFALLYFTGSEK--------FDT 770
            |||:|||||.|.::..::..|:.|:|.....:.|.||:|.|.:|.|    ||.|        |:|
  Fly   653 ECGTDALRFTLMSHNIKSHFISFDVNACHTNKLFLNKVWQAMRFTL----GSAKGLGISLHQFET 713

  Fly   771 ELSASAAINQMDAWILSRLAAAIEACNTGFESYDFAAATSACYAFWLYDLCDVYLECLKPIFQSG 835
            ....:..:  .|.||:.|||..:..|:..:.:|:|..||:|...|:...|||.|||..||...:.
  Fly   714 LEGVNLGL--WDRWIVGRLAETLSVCSQSYSNYNFHLATAALKTFFYQYLCDTYLETTKPAIGNR 776

  Fly   836 SEEQQTAARRTLYVCLDYGLRLLSPFMPFITEELYQRLPRANPAPSICVASYPSNTSWRSTKIES 900
            |.:..... .||..||.:||:.::|:.||:..||.|.:| .|....:        :.::..|:|.
  Fly   777 SADAYIHV-GTLTACLSWGLQAMAPYAPFVASELLQHVP-LNIELKL--------SDYKDEKLEE 831

  Fly   901 DVEFVQKAARIIRSARSDYNLPNKVKTEVYIVCTDSVPSEILKRYASDLATISYCSNV---VFDS 962
            :|..:......:|..:|...:..:...::.:...::....:|:|:...:..:|.|.:|   :||
  Fly   832 EVNEIVNICHNVRQVKSRNEISKRHHPQLSLFAQNTDSEGVLRRHLPQIKVLSRCEDVELELFD- 895

  Fly   963 PAPQGCAILTVTGQCEVHLLLKGLVEADKEIAKLQKKSDQLVQTVGKLTQ-AIQAADYATKVPA- 1025
                                         |.:|:.|:.... .|.|.|.. .::.:|.....|.
  Fly   896 -----------------------------ESSKISKQLSYF-STAGALCSFGLKLSDGLDLTPEK 930

  Fly  1026 --EVQEANETKLCESRAEIERIAAAI--ETLKLM 1055
              |:|:||..||.:...|::|....:  |..:||
  Fly   931 RDEMQKANAKKLKKLVTELQRYRMRLDNEAFQLM 964

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ValRS	NP_001260946.1	PTZ00419	80..1053	CDD:240411	378/1005 (38%)
ValRS-m	NP_648268.1	PTZ00419	23..989	CDD:240411	380/1009 (38%)