Protein Alignment Prosalpha1 and PUP2

DIOPT Version :10

• Sequence 1: NP_524837.2
• Gene: Prosalpha1 / 45780
• FlyBaseID: FBgn0263121
• Length: 244
• Species: Drosophila melanogaster
• Sequence 2: NP_011769.1
• Gene: PUP2 / 853168
• SGDID: S000003485
• Length: 260
• Species: Saccharomyces cerevisiae
• Alignment Length: 242
• Identity: 64/242 - (26%)
• Similarity: 130/242 - (53%)
• Gaps: 8/242 - (3%)

  Fly     9 FDRHITIFSPEGRLYQVEYAFKAIAQENITTVALKSGDCAVVATQKKVTEKNIVPETVTHLFRIT 73
            :||.::.|||||||:||||:.:|| :...|.:.:.:.:..|:..:|:.|...:..:::..:..|.
Yeast     8 YDRGVSTFSPEGRLFQVEYSLEAI-KLGSTAIGIATKEGVVLGVEKRATSPLLESDSIEKIVEID 71

  Fly    74 KDIGCAMTGRIADSRSQVQKARYEAANFRYKYGYEMPVDVLCRRIADINQVYTQNAE------MR 132
            :.|||||:|..||:||.::.||..|......|..::.|:.|.:.:.|:...:.:.|.      .|
Yeast    72 RHIGCAMSGLTADARSMIEHARTAAVTHNLYYDEDINVESLTQSVCDLALRFGEGASGEERLMSR 136

  Fly   133 PLGCSMVLIAYDNEIGPSVYKTDPAGYFSGFKACSVGAKTLEANSYLEKKYKPNLSEEKAIQLAI 197
            |.|.::::..:|.:.|..::..:|:|.|..:.|.::|:.:..|.:.|..::..:|:.::|..|.:
Yeast   137 PFGVALLIAGHDADDGYQLFHAEPSGTFYRYNAKAIGSGSEGAQAELLNEWHSSLTLKEAELLVL 201

  Fly   198 SCLSSVLAIDFKPNGIEIGVVSKSDPTFRILDEREIEEHLTKIAEKD 244
            ..|..|:......|..::..::|.| .|:|.|..:..|.:.::.||:
Yeast   202 KILKQVMEEKLDENNAQLSCITKQD-GFKIYDNEKTAELIKELKEKE 247

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha1	NP_524837.2	proteasome_alpha_type_6	8..218	CDD:239723	56/214 (26%)
PUP2	NP_011769.1	proteasome_alpha_type_5	8..222	CDD:239722	56/214 (26%)