DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosalpha1 and PAA2

DIOPT Version :9

Sequence 1:	NP_524837.2	Gene:	Prosalpha1 / 45780	FlyBaseID:	FBgn0263121	Length:	244	Species:	Drosophila melanogaster
Sequence 2:	NP_178641.1	Gene:	PAA2 / 815135	AraportID:	AT2G05840	Length:	246	Species:	Arabidopsis thaliana

Alignment Length:	246	Identity:	138/246 - (56%)
Similarity:	173/246 - (70%)	Gaps:	2/246 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSRGSSAGFDRHITIFSPEGRLYQVEYAFKAIAQENITTVALKSGDCAVVATQKKVTEKNIVPET 65
            |||||.||:|||||||||||||:||||||||:....||::.::..|...|.|||||.:|.:...:
plant     1 MSRGSGAGYDRHITIFSPEGRLFQVEYAFKAVKAAGITSIGVRGKDSVCVVTQKKVPDKLLDQSS 65

  Fly    66 VTHLFRITKDIGCAMTGRIADSRSQVQKARYEAANFRYKYGYEMPVDVLCRRIADINQVYTQNAE 130
            |:|||.:||.:|...||..|||||.||:||.|||.||::||||||.|:|.:.|||.:|||||:|.
plant    66 VSHLFPVTKYLGLLATGMTADSRSLVQQARNEAAEFRFQYGYEMPADILAKWIADKSQVYTQHAY 130

  Fly   131 MRPLGCSMVLIAYDNEIGPSVYKTDPAGYFSGFKACSVGAKTLEANSYLEKKYK--PNLSEEKAI 193
            |||||...:::..|.|.||.:||.||||:|.|.||.|.|.|..||.::||||.|  |..:.::.:
plant   131 MRPLGVVAMVLGIDEERGPLLYKCDPAGHFYGHKATSAGMKEQEAVNFLEKKMKENPAFTYDETV 195

  Fly   194 QLAISCLSSVLAIDFKPNGIEIGVVSKSDPTFRILDEREIEEHLTKIAEKD 244
            |.|||.|.|||..|||...||:|||...||.||.|...||:||||.|:|:|
plant   196 QTAISALQSVLQEDFKATEIEVGVVRADDPLFRSLRTEEIDEHLTAISERD 246

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha1	NP_524837.2	PRE1	7..243	CDD:223711	131/237 (55%)
Prosalpha1	NP_524837.2	proteasome_alpha_type_6	8..218	CDD:239723	116/211 (55%)
PAA2	NP_178641.1	proteasome_alpha_type_6	8..220	CDD:239723	116/211 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	180	1.000	Domainoid score	I1047
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2085
Inparanoid	1	1.050	266	1.000	Inparanoid score	I942
OMA	1	1.010	-	-		QHG53623
OrthoDB	1	1.010	-	-		D1222564at2759
OrthoFinder	1	1.000	-	-		FOG0002933
OrthoInspector	1	1.000	-	-		otm2462
orthoMCL	1	0.900	-	-		OOG6_102240
Panther	1	1.100	-	-	O	PTHR11599
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1933
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.930