Protein Alignment Prosalpha1 and PSMB5

DIOPT Version :10

• Sequence 1: NP_524837.2
• Gene: Prosalpha1 / 45780
• FlyBaseID: FBgn0263121
• Length: 244
• Species: Drosophila melanogaster
• Sequence 2: NP_002788.1
• Gene: PSMB5 / 5693
• HGNCID: 9542
• Length: 263
• Species: Homo sapiens
• Alignment Length: 167
• Identity: 44/167 - (26%)
• Similarity: 70/167 - (41%)
• Gaps: 20/167 - (11%)

  Fly    38 TTVALKSGDCAVVATQKKVTE-KNIVPETVTHLFRITKDIGCAMTGRIAD----SRSQVQKAR-Y 96
            ||:|.|.....:||...:.|. ..|..:||..:..|...:...|.|..||    .|...::.| |
Human    61 TTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLARQCRIY 125

  Fly    97 EAANFRYKYGYEMPVDVLCRRIADINQVYTQNAEMRPLGCSM--VLIAYDNEIGPSVYKTDPAGY 159
            |..|..     .:.|....:.:|  |.||    :.:.:|.||  ::..:|.. ||.:|..|..|.
Human   126 ELRNKE-----RISVAAASKLLA--NMVY----QYKGMGLSMGTMICGWDKR-GPGLYYVDSEGN 178

  Fly   160 FSGFKACSVGAKTLEANSYLEKKYKPNLSEEKAIQLA 196
            .......|||:.::.|...:::.|..:|..|:|..||
Human   179 RISGATFSVGSGSVYAYGVMDRGYSYDLEVEQAYDLA 215

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha1	NP_524837.2	proteasome_alpha_type_6	8..218	CDD:239723	44/167 (26%)
PSMB5	NP_002788.1	proteasome_beta_type_5	60..247	CDD:239730	44/167 (26%)