DRSC/TRiP Functional Genomics Resources

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Protein Alignment Prosalpha1 and PSMA6

DIOPT Version :9

Sequence 1:NP_524837.2 Gene:Prosalpha1 / 45780 FlyBaseID:FBgn0263121 Length:244 Species:Drosophila melanogaster
Sequence 2:NP_002782.1 Gene:PSMA6 / 5687 HGNCID:9535 Length:246 Species:Homo sapiens


Alignment Length:246 Identity:164/246 - (66%)
Similarity:200/246 - (81%) Gaps:2/246 - (0%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MSRGSSAGFDRHITIFSPEGRLYQVEYAFKAIAQENITTVALKSGDCAVVATQKKVTEKNIVPET 65
            ||||||||||||||||||||||||||||||||.|..:|:||::..||||:.|||||.:|.:...|
Human     1 MSRGSSAGFDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKLLDSST 65

  Fly    66 VTHLFRITKDIGCAMTGRIADSRSQVQKARYEAANFRYKYGYEMPVDVLCRRIADINQVYTQNAE 130
            |||||:||::|||.|||..||||||||:|||||||::||||||:|||:||:|||||:||||||||
Human    66 VTHLFKITENIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIADISQVYTQNAE 130

  Fly   131 MRPLGCSMVLIAYDNEIGPSVYKTDPAGYFSGFKACSVGAKTLEANSYLEKKYKPNL--SEEKAI 193
            ||||||.|:||..|.|.||.|||.|||||:.||||.:.|.|..|:.|:||||.|...  :.|:.:
Human   131 MRPLGCCMILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLEKKVKKKFDWTFEQTV 195

  Fly   194 QLAISCLSSVLAIDFKPNGIEIGVVSKSDPTFRILDEREIEEHLTKIAEKD 244
            :.||:|||:||:|||||:.||:|||:..:|.||||.|.||:.||..:||:|
Human   196 ETAITCLSTVLSIDFKPSEIEVGVVTVENPKFRILTEAEIDAHLVALAERD 246

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Prosalpha1NP_524837.2 PRE1 7..243 CDD:223711 156/237 (66%)
proteasome_alpha_type_6 8..218 CDD:239723 142/211 (67%)
PSMA6NP_002782.1 proteasome_alpha_type_6 8..220 CDD:239723 142/211 (67%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165159572
Domainoid 1 1.000 245 1.000 Domainoid score I2189
eggNOG 1 0.900 - - E1_COG0638
Hieranoid 1 1.000 - -
Homologene 1 1.000 - - H2085
Inparanoid 1 1.050 336 1.000 Inparanoid score I2407
Isobase 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG53623
OrthoDB 1 1.010 - - D1222564at2759
OrthoFinder 1 1.000 - - FOG0002933
OrthoInspector 1 1.000 - - oto90870
orthoMCL 1 0.900 - - OOG6_102240
Panther 1 1.100 - - LDO PTHR11599
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R1008
SonicParanoid 1 1.000 - - X1933
SwiftOrtho 1 1.000 - -
TreeFam 1 0.960 - -
User_Submission 00.000 Not matched by this tool.
1716.800

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