Protein Alignment Prosalpha1 and PSMA4

DIOPT Version :10

• Sequence 1: NP_524837.2
• Gene: Prosalpha1 / 45780
• FlyBaseID: FBgn0263121
• Length: 244
• Species: Drosophila melanogaster
• Sequence 2: NP_002780.1
• Gene: PSMA4 / 5685
• HGNCID: 9533
• Length: 261
• Species: Homo sapiens
• Alignment Length: 245
• Identity: 72/245 - (29%)
• Similarity: 133/245 - (54%)
• Gaps: 8/245 - (3%)

  Fly     6 SAGFDRHITIFSPEGRLYQVEYAFKAIAQENITTVALKSGDCAVVATQKKVTEKNIVPETV--TH 68
            |..:|...|||||||||||||||.:||.... |.:.:.:.|..::|.:::...| ::.|..  ..
Human     2 SRRYDSRTTIFSPEGRLYQVEYAMEAIGHAG-TCLGILANDGVLLAAERRNIHK-LLDEVFFSEK 64

  Fly    69 LFRITKDIGCAMTGRIADSRSQVQKARYEAANFRYKYGYEMPVDVLCRRIADINQVYTQNAEMRP 133
            ::::.:|:.|::.|..:|:.....:.|..|..:..:|...:|.:.|...:.||.|.|||....||
Human    65 IYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQFGGKRP 129

  Fly   134 LGCSMVLIAYDNEIGPSVYKTDPAGYFSGFKACSVGAKTLEANSYLEKKYKP-NLSEEKAIQLAI 197
            .|.|::.|.:|...|..:|::||:|.:.|:||..:|..:..|.|.|::.||. .::.:.|:.|||
Human   130 FGVSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYKEGEMTLKSALALAI 194

  Fly   198 SCLSSVLAID-FKPNGIEIGVVSKSD--PTFRILDEREIEEHLTKIAEKD 244
            ..|:..:.:. .....:||..:::.:  ...|:|.::|:|:.:.|..|::
Human   195 KVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLIKKHEEEE 244

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha1	NP_524837.2	proteasome_alpha_type_6	8..218	CDD:239723	65/213 (31%)
PSMA4	NP_002780.1	proteasome_alpha_type_4	3..216	CDD:239721	65/214 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	240..261		1/5 (20%)