DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosalpha1 and psma6b

DIOPT Version :9

Sequence 1:	NP_524837.2	Gene:	Prosalpha1 / 45780	FlyBaseID:	FBgn0263121	Length:	244	Species:	Drosophila melanogaster
Sequence 2:	NP_001002589.1	Gene:	psma6b / 436862	ZFINID:	ZDB-GENE-040718-329	Length:	246	Species:	Danio rerio

Alignment Length:	246	Identity:	163/246 - (66%)
Similarity:	203/246 - (82%)	Gaps:	2/246 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSRGSSAGFDRHITIFSPEGRLYQVEYAFKAIAQENITTVALKSGDCAVVATQKKVTEKNIVPET 65
            ||||||||||||||||||||||||||||||||.|..:|:||::..|||:|.|||||.:|.:...|
Zfish     1 MSRGSSAGFDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAIVVTQKKVPDKLLDSST 65

  Fly    66 VTHLFRITKDIGCAMTGRIADSRSQVQKARYEAANFRYKYGYEMPVDVLCRRIADINQVYTQNAE 130
            ||||||||::|||.|:|..||||||||:|||||||::||||||:|||:||:|||||:||||||||
Zfish    66 VTHLFRITENIGCVMSGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIADISQVYTQNAE 130

  Fly   131 MRPLGCSMVLIAYDNEIGPSVYKTDPAGYFSGFKACSVGAKTLEANSYLEKKYKPNL--SEEKAI 193
            ||||||.|::|..|.|:||.|||.|||||:.||||.:.|.|..||.|:||||.|..|  :.|:|:
Zfish   131 MRPLGCCMIVIGLDEELGPQVYKCDPAGYYCGFKATAAGVKQTEATSFLEKKVKKKLDWTFEQAV 195

  Fly   194 QLAISCLSSVLAIDFKPNGIEIGVVSKSDPTFRILDEREIEEHLTKIAEKD 244
            :.||:||::||:|||||:.:||||::..||.||||.|.|::.||..::|:|
Zfish   196 ETAITCLTTVLSIDFKPSELEIGVITAEDPKFRILSESEVDTHLVSLSERD 246

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha1	NP_524837.2	PRE1	7..243	CDD:223711	155/237 (65%)
Prosalpha1	NP_524837.2	proteasome_alpha_type_6	8..218	CDD:239723	143/211 (68%)
psma6b	NP_001002589.1	PRE1	7..245	CDD:223711	155/237 (65%)
psma6b	NP_001002589.1	proteasome_alpha_type_6	8..220	CDD:239723	143/211 (68%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595764
Domainoid	1	1.000	248	1.000	Domainoid score	I2104
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2085
Inparanoid	1	1.050	337	1.000	Inparanoid score	I2357
OMA	1	1.010	-	-		QHG53623
OrthoDB	1	1.010	-	-		D1222564at2759
OrthoFinder	1	1.000	-	-		FOG0002933
OrthoInspector	1	1.000	-	-		otm24775
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR11599
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1008
SonicParanoid	1	1.000	-	-		X1933
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.900