DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosalpha1 and psma6

DIOPT Version :9

Sequence 1:	NP_524837.2	Gene:	Prosalpha1 / 45780	FlyBaseID:	FBgn0263121	Length:	244	Species:	Drosophila melanogaster
Sequence 2:	NP_989113.1	Gene:	psma6 / 394718	XenbaseID:	XB-GENE-943786	Length:	246	Species:	Xenopus tropicalis

Alignment Length:	246	Identity:	166/246 - (67%)
Similarity:	200/246 - (81%)	Gaps:	2/246 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSRGSSAGFDRHITIFSPEGRLYQVEYAFKAIAQENITTVALKSGDCAVVATQKKVTEKNIVPET 65
            ||||||||||||||||||||||||||||||||.|..:|:||::..|||||.||:||.:|.:...|
Frog     1 MSRGSSAGFDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVVVTQRKVPDKLLDSNT 65

  Fly    66 VTHLFRITKDIGCAMTGRIADSRSQVQKARYEAANFRYKYGYEMPVDVLCRRIADINQVYTQNAE 130
            ||||||||:.|||.|||..||||||||:|||||||::||||||:|||:||:|||||:||||||||
Frog    66 VTHLFRITESIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIADISQVYTQNAE 130

  Fly   131 MRPLGCSMVLIAYDNEIGPSVYKTDPAGYFSGFKACSVGAKTLEANSYLEKKYKPNL--SEEKAI 193
            ||||||.|:||..|.|.||.|:|.|||||:.||||.:.|.|..||.|:||||.|..|  :.|:.:
Frog   131 MRPLGCCMILIGVDEENGPQVFKCDPAGYYCGFKATTAGVKQTEATSFLEKKVKKKLDWTYEQTL 195

  Fly   194 QLAISCLSSVLAIDFKPNGIEIGVVSKSDPTFRILDEREIEEHLTKIAEKD 244
            :.||||||:||:|||||:.:|:|||:..||.||:|.|.||:.||..:||:|
Frog   196 ETAISCLSTVLSIDFKPSELEVGVVTVEDPKFRVLTEAEIDVHLVALAERD 246

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha1	NP_524837.2	PRE1	7..243	CDD:223711	158/237 (67%)
Prosalpha1	NP_524837.2	proteasome_alpha_type_6	8..218	CDD:239723	144/211 (68%)
psma6	NP_989113.1	proteasome_alpha_type_6	8..220	CDD:239723	144/211 (68%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	247	1.000	Domainoid score	I2116
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H2085
Inparanoid	1	1.050	338	1.000	Inparanoid score	I2335
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1222564at2759
OrthoFinder	1	1.000	-	-		FOG0002933
OrthoInspector	1	1.000	-	-		oto104658
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1008
SonicParanoid	1	1.000	-	-		X1933
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.090