Protein Alignment Prosalpha1 and Prosalpha4

DIOPT Version :10

• Sequence 1: NP_524837.2
• Gene: Prosalpha1 / 45780
• FlyBaseID: FBgn0263121
• Length: 244
• Species: Drosophila melanogaster
• Sequence 2: XP_315431.3
• Gene: Prosalpha4 / 1276122
• VectorBaseID: AGAMI1_010744
• Length: 249
• Species: Anopheles gambiae
• Alignment Length: 249
• Identity: 80/249 - (32%)
• Similarity: 133/249 - (53%)
• Gaps: 17/249 - (6%)

  Fly     6 SAGFDRHITIFSPEGRLYQVEYAFKAIAQENITTVALKSGDCAVVATQKKVTEKNIVPETVTHLF 70
            |:.:||.||:|||:|.|.|||||.:|: ::..|.:.::..|..|:..:||...|.....||..:.
Mosquito     2 SSRYDRAITVFSPDGHLLQVEYAQEAV-RKGSTAIGVRGKDVVVLGVEKKSVAKLQEERTVRKIC 65

  Fly    71 RITKDIGCAMTGRIADSRSQVQKARYEAANFRYKYGYEMPV--DVLCRRIADINQVYTQNAEMRP 133
            .:...:..|..|..||:|..:.:|:.:..:  :|...|.||  :.:.|.||::.|.:||:...||
Mosquito    66 LLDHHVVMAFAGLTADARVLINRAQVQCQS--HKLSEEDPVTLEYITRYIAELKQKHTQSNGRRP 128

  Fly   134 LGCSMVLIAYDNEIGPSVYKTDPAGYFSGFKACSVGAKTLEANSYLEKKYKPNL--SEEKAIQLA 196
            .|.|.::..:|.:..|.:|||:|:|.:..:||.:.|........:||:.|.|..  :||..|.||
Mosquito   129 FGISCLIGGFDYDGVPHLYKTEPSGVYCEWKANATGRSAKTVREFLEEHYSPAAVSTEEGTITLA 193

  Fly   197 ISCLSSVLAIDFKPNGIEIGVVSKSDPTFRILDEREIEEHLTKI-------AEK 243
            |..|..|:....|  .:|:.|:.:.:| .::||.:.|||::.||       |||
Mosquito   194 IRALLEVVQSGQK--SLEVAVMRRDEP-MKMLDAQTIEEYVKKIELAKEEEAEK 244

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha1	NP_524837.2	proteasome_alpha_type_6	8..218	CDD:239723	67/213 (31%)
Prosalpha4	XP_315431.3	proteasome_alpha_type_7	5..213	CDD:239724	67/212 (32%)