DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosalpha1 and PSMB11

DIOPT Version :9

Sequence 1:	NP_524837.2	Gene:	Prosalpha1 / 45780	FlyBaseID:	FBgn0263121	Length:	244	Species:	Drosophila melanogaster
Sequence 2:	NP_001093250.1	Gene:	PSMB11 / 122706	HGNCID:	31963	Length:	300	Species:	Homo sapiens

Alignment Length:	120	Identity:	28/120 - (23%)
Similarity:	51/120 - (42%)	Gaps:	25/120 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   140 LIAYDNEIGPSVYKTDPAGYFSGFK----ACSVGAKTLEANSYLEKKYKPNLSEEKAIQLAISCL 200
            |..:|.. ||.::..    |..|.:    ..|||:.:..|...|::.|:.::|.::|..||...:
Human   150 LCGWDRS-GPELFYV----YSDGTRLQGDIFSVGSGSPYAYGVLDRGYRYDMSTQEAYALARCAV 209

  Fly   201 S-----------SVLAIDFKPNGIEIGVVSKSDPTFRILDEREIEEHLTKIAEKD 244
            :           ||.....:.:|.|  .||:||.....:   |:::.|....|:|
Human   210 AHATHRDAYSGGSVDLFHVRESGWE--HVSRSDACVLYV---ELQKLLEPEPEED 259

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha1	NP_524837.2	PRE1	7..243	CDD:223711	26/117 (22%)
Prosalpha1	NP_524837.2	proteasome_alpha_type_6	8..218	CDD:239723	20/92 (22%)
PSMB11	NP_001093250.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..23
		proteasome_beta_type_5	50..237	CDD:239730	20/93 (22%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	255..300		2/5 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900