DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mei-P26 and F40G9.12

DIOPT Version :9

Sequence 1:	NP_001356936.1	Gene:	mei-P26 / 45775	FlyBaseID:	FBgn0026206	Length:	1310	Species:	Drosophila melanogaster
Sequence 2:	NP_497167.2	Gene:	F40G9.12 / 185559	WormBaseID:	WBGene00018247	Length:	190	Species:	Caenorhabditis elegans

Alignment Length:	163	Identity:	41/163 - (25%)
Similarity:	57/163 - (34%)	Gaps:	56/163 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   152 LMIKDGDKLCKLCSLRLV-----MPRILSCLHVFCEDCLQAVVSKDTMSASSPNSCSSSSFDGSE 211
            :.|.||...||:|.....     .||:|||.|.:||.|:|.:       ||..|:
Worm    20 MYIDDGRPECKICYKNYETSGDHCPRVLSCGHTYCEICIQEL-------ASLRNN---------- 67

  Fly   212 HQNRLSAVFIECPVCKQETPLGPKGIK-----------ALPCDYIVTNILDLSNLESEHIVCTSC 265
                   |.|.||.|   |.|.....|           |.|.:::|..|  |:....:.:.|..|
Worm    68 -------VVIACPYC---TKLSIISFKHWILTSFRVSSAFPTNFLVLEI--LNGKAKDMLQCGVC 120

  Fly   266 K--SKEEAISR---------CNDCANFLCNGCD 287
            :  ...:.|.|         |.||....|..|:
Worm   121 QLTYSSQRIPRIHPSCGKSVCEDCKEHECKACE 153

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mei-P26	NP_001356936.1	RING_Ubox	158..230	CDD:354325	21/76 (28%)
		BBOX	321..360	CDD:237988
		BBC	369..494	CDD:128778
		NHL_brat_like	913..1186	CDD:271329
		NHL repeat	936..972	CDD:271329
		NHL repeat	983..1025	CDD:271329
		NHL repeat	1028..1064	CDD:271329
		NHL repeat	1068..1107	CDD:271329
		NHL repeat	1112..1151	CDD:271329
		NHL repeat	1157..1183	CDD:271329
F40G9.12	NP_497167.2	RING_Ubox	28..75	CDD:388418	20/70 (29%)
F40G9.12	NP_497167.2	RING-HC finger (C3HC4-type)	29..75	CDD:319361	20/69 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D489543at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010