DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mei-P26 and F43G6.8

DIOPT Version :9

Sequence 1:	NP_001356936.1	Gene:	mei-P26 / 45775	FlyBaseID:	FBgn0026206	Length:	1310	Species:	Drosophila melanogaster
Sequence 2:	NP_496523.1	Gene:	F43G6.8 / 174815	WormBaseID:	WBGene00009660	Length:	263	Species:	Caenorhabditis elegans

Alignment Length:	91	Identity:	23/91 - (25%)
Similarity:	37/91 - (40%)	Gaps:	34/91 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   159 KLCKLCSLRL-----VMPRILSCLHVFCEDCLQAVVSKDTMSASSPNSCSSSSFDGSEHQNRLSA 218
            |||::|:.:.     .:||:|.|.|..|..|::.:                ...||
Worm   197 KLCEICAHQFSHSDEYVPRVLVCGHTLCTSCIEKL----------------DVGDG--------- 236

  Fly   219 VFIECPVCKQETPLGPKGIKALPCDY 244
              |.||.|:..|.:  |.|:|||.::
Worm   237 --IRCPFCRTWTNM--KRIEALPKNF 258

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mei-P26	NP_001356936.1	RING_Ubox	158..230	CDD:354325	17/75 (23%)
		BBOX	321..360	CDD:237988
		BBC	369..494	CDD:128778
		NHL_brat_like	913..1186	CDD:271329
		NHL repeat	936..972	CDD:271329
		NHL repeat	983..1025	CDD:271329
		NHL repeat	1028..1064	CDD:271329
		NHL repeat	1068..1107	CDD:271329
		NHL repeat	1112..1151	CDD:271329
		NHL repeat	1157..1183	CDD:271329
F43G6.8	NP_496523.1	SMC_prok_B	<15..>188	CDD:274008
F43G6.8	NP_496523.1	RING-HC_TRIM32_C-VII	198..243	CDD:319501	15/71 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D489543at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920