Protein Alignment mei-P26 and trim3

DIOPT Version :9

• Sequence 1: NP_001356936.1
• Gene: mei-P26 / 45775
• FlyBaseID: FBgn0026206
• Length: 1310
• Species: Drosophila melanogaster
• Sequence 2: XP_031753313.1
• Gene: trim3 / 100497041
• XenbaseID: XB-GENE-5826034
• Length: 790
• Species: Xenopus tropicalis
• Alignment Length: 1075
• Identity: 214/1075 - (19%)
• Similarity: 360/1075 - (33%)
• Gaps: 380/1075 - (35%)

  Fly   150 SGLMIKDGDK--------------LCKLCSLRLVMPRILSCLHVFCEDCLQAVVSKDTMSASSPN 200
            |.:.:::|||              :|.:|..|..:|::|.|||.|||.|||:.:...:::.|
 Frog    41 SHVRLREGDKMASPVVRQIDKQFLICSICLERYHIPKVLPCLHTFCERCLQSYIPPQSLTLS--- 102

  Fly   201 SCSSSSFDGSEHQNRLSAVFIECPVCKQETPLGPKGIKALPCDYIVTNILDLSNLESEHIVCTSC 265
                                  ||||:|.:.|..||:.||..::.:||::::.....|     |.
 Frog   103 ----------------------CPVCRQTSILPEKGVSALQNNFFITNLMEVLQRSPE-----SG 140

  Fly   266 KSKEEAISRCNDCANFLCNGCDNAHKYMRCFENHHVVRIEDLTKNVHDKLIIHKPVFCPQHVSEN 330
            :.::..:......|.                                      .|:.||.|..:.
 Frog   141 RQEQSVLPSEGQEAG--------------------------------------TPLSCPNHQGKT 167

  Fly   331 LKYYCFTCQVPTCNDCLLSDHKGSDHHYETATVAEQAV----RADLEETLSDTLKKADYCNDAGS 391
            ::|||..|:...|.:|...:|:      |..||..:.|    :|.|...|.....:......|..
 Frog   168 MEYYCGPCETAMCVECTEGEHR------EHCTVPLRDVVEQHKASLRNQLESIRSRIPQLTSAID 226

  Fly   392 NLGSALTELQSQHDTVRQQIEDAYKCYKRMLESIKDQMLNELGRLHSDRELKIMDLMQSMENTMG 456
            .:.....:|..:.::...:|..|::..::.|:..|..:|.:|..:...::..:...:.|:...:.
 Frog   227 LVSDISRQLSERKNSAVNEICSAFEELEKALQQRKSALLQDLEAICVGKQKVLQSQLSSLRQGLD 291

  Fly   457 KLQHAAQFGQRAVDKANSIEFLLLKPIISAQCLNLMEQTPKCDINYQLQFDSKPEMFEQFAREMF 521
            .::.:.:|.::|:...:..|.||::..:|.: ||                       |..||:.
 Frog   292 NMESSVRFTEQALGHGSETEVLLVRKQMSER-LN-----------------------ELAARDF- 331

  Fly   522 GKFQTDHIDSSPKKLGMTQQLQQQQQQQQQLQQQQHQHQHQVQQQQHHHQQQQQQKQQVQHQQQQ 586
                                                         ..|.||..|.:.:|:.:..:
 Frog   332 ---------------------------------------------PLHPQQNPQLEFRVETEGLR 351

  Fly   587 QKLQLQQQQQHQHNSNNLIVGHRGSSSVQGRLTSAV-FSPISLPSSLQSSFDGDTNSVMSNFSMM 650
            :.||         |...|:.            |:|| ::.::....|:.:..|...||......|
 Frog   352 RSLQ---------NLGALLT------------TNAVAYASVATGEGLRQALVGQQTSVTVTTKDM 395

  Fly   651 DSPPQPSSQQQLPSAQQQSQQQQQQQQQQQAVVLQQVQQQQKHQQHQVQQQQQQQVLHQPTSAQS 715
            |
 Frog   396 D---------------------------------------------------------------- 396

  Fly   716 MPQQLGQLVAPQGIVQQAGHVNLNAGPGPNISINGLGAGGPPPSFSMLEYNISRLASLTETMPDT 780
                 |:||       ::|:..|.|      .|.|                           ||
 Frog   397 -----GELV-------RSGNATLKA------QITG---------------------------PD- 415

  Fly   781 LNDALAVGGGAAGPV---PNVVAQVPGGSAVTGAAVVGASHAHQQQSQAVMPASAVTPTQPITLA 842
                   ||...|.|   .|...:|.....|.|..::......|....:.....|:.|
 Frog   416 -------GGAQEGEVTDNKNGTYEVLYTLRVEGEHLLSLRLYGQPLRGSPYRVRAIKP------- 466

  Fly   843 DILSGDQRALNNLQALAKLGLNNNDFCMPPATSPSLQSLNPIVGGVEDMGLNNFH----AVAAPG 903
                ||                     :||:.....:.:....||         |    ||..|
 Frog   467 ----GD---------------------VPPSPEDVKRRVKSPSGG---------HIRQKAVRRP- 496

  Fly   904 TTSVVTGRNKATPM--QIRCKFGSLGTAKGQFNSPHGFCLGVDEEIIVADTNNHRIEVFDKMGAL 966
            ::...|.:.|..|:  ::..:.||.|..||:|::..|.....:..|:|||:||..|:||...|..
 Frog   497 SSMYSTNKKKENPIEDEMILRVGSRGRDKGEFSNLQGISASCNNRIVVADSNNQCIQVFTNDGQF 561

  Fly   967 KFQFGVAGKEEGQLWYPRKVAVMHNNGKFVVCDRGNERSRMQIFSKCGHFMRKIAIRYIDIVAGL 1031
            |.:|||.|:..|||..|..||| ..||..:|.|..|.  .:.|||..|.|..||.:..:....|:
 Frog   562 KLRFGVRGRSPGQLQRPTGVAV-DMNGDIIVADYDNR--WVSIFSPEGKFKNKIGVGRLMGPKGV 623

  Fly  1032 AVTAKGHIVAVDSVSPTVFVISEEGELVRWFDCSDYMREPSD------------IAIRD-NDFYV 1083
            ||...||::.||:.|..:|:....|:||..|..    |.|.|            :|:.: |:..|
 Frog   624 AVDRNGHLIVVDNKSCCIFIFQSNGKLVGRFGA----RGPGDKQQPGALDGPHFVAVNNKNEIVV 684

  Fly  1084 CDFKGHCVAVFQDDGTFLYRI-----GNEKVTCFPNGIDISNAGDVLIGDSHGNRFHVACYSREG 1143
            .||..|.|.|:..||.|||:.     ||.:... |.|:.:.:.|::::.|...:|..|  :...|
 Frog   685 TDFHNHSVKVYSADGEFLYKFGSHGEGNGQFNA-PTGVAVDSNGNIIVADWGNSRIQV--FDSSG 746

  Fly  1144 ALQSEFECPHVKVSRCCGLKITSEGYVVTLAKNNH 1178
            :..|........:....||.:||||:||.....||
 Frog   747 SFLSYINTMGDPLYGPQGLALTSEGHVVVADSGNH 781

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mei-P26	NP_001356936.1	RING_Ubox	158..230	CDD:354325	22/85 (26%)
		BBOX	321..360	CDD:237988	10/38 (26%)
		BBC	369..494	CDD:128778	20/124 (16%)
		NHL_brat_like	913..1186	CDD:271329	92/286 (32%)
		NHL repeat	936..972	CDD:271329	13/35 (37%)
		NHL repeat	983..1025	CDD:271329	16/41 (39%)
		NHL repeat	1028..1064	CDD:271329	13/35 (37%)
		NHL repeat	1068..1107	CDD:271329	17/56 (30%)
		NHL repeat	1112..1151	CDD:271329	8/38 (21%)
		NHL repeat	1157..1183	CDD:271329	10/22 (45%)
trim3	XP_031753313.1	RAD18	54..>150	CDD:227719	29/125 (23%)
		RING_Ubox	63..107	CDD:418438	18/68 (26%)
		Bbox2_TRIM3_C-VII	154..198	CDD:380883	15/87 (17%)
		BBC	203..328	CDD:128778	21/148 (14%)
		IG_FLMN	369..463	CDD:214720	25/210 (12%)
		NHL_TRIM2_like	513..790	CDD:271330	90/279 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D133242at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010