DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mei-P26 and nhlrc3

DIOPT Version :9

Sequence 1:	NP_001356936.1	Gene:	mei-P26 / 45775	FlyBaseID:	FBgn0026206	Length:	1310	Species:	Drosophila melanogaster
Sequence 2:	XP_002936773.2	Gene:	nhlrc3 / 100497010	XenbaseID:	XB-GENE-988782	Length:	344	Species:	Xenopus tropicalis

Alignment Length:	243	Identity:	52/243 - (21%)
Similarity:	94/243 - (38%)	Gaps:	65/243 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   986 VAVMHNNGKFVVCDRGNERSRMQIFSKCGHFMRKIAIRYIDIVAGL-AV-TAKGHIVAVDSVSP- 1047
            |||...|....|..||...|::.:|::.|:|.::.....||:..|: || |.|.|.:.:..|..
Frog    69 VAVDPTNSLVYVAQRGENVSKVLVFTEEGYFKQQWNTDSIDMPHGIFAVSTDKEHSIWITDVGQG 133

  Fly  1048 ----TVFVISEEGELVR---------------WFDCSDYMREPSDIAIRDN-DFYVCDFKG---H 1089
                ||...|..|:|::               .||      :|::|.:.:: |.|:.|..|   :
Frog   134 NFGHTVKKYSPSGKLLQVLGTAGKSGSALDPLQFD------QPAEIFVENSGDLYIVDGDGGLNN 192

  Fly  1090 CVAVFQDDGTFLYRIGNEKVT----CFPNGIDISNAGDVLIGDSHGNRFHV-------------A 1137
            .:..|..|...|:.:|.....    ..|:.:.:...|.|.:.|....|...             :
Frog   193 RILKFTKDFWLLWTLGGRGTKPGQFFIPHSVTVDEVGRVWVADRGNKRMQAFDKTSGEWIGTWSS 257

  Fly  1138 CYSREGALQSEFECPHVKVSRCCGLKITSE-GYVVTLAKNNHHVLVLN 1184
            |::.:|        |:       .:::|:: .|.|....|.:.||.|:
Frog   258 CFTEDG--------PY-------SVRLTADKQYFVVAQLNINRVLFLS 290

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mei-P26	NP_001356936.1	RING_Ubox	158..230	CDD:354325
		BBOX	321..360	CDD:237988
		BBC	369..494	CDD:128778
		NHL_brat_like	913..1186	CDD:271329	52/243 (21%)
		NHL repeat	936..972	CDD:271329
		NHL repeat	983..1025	CDD:271329	11/38 (29%)
		NHL repeat	1028..1064	CDD:271329	13/57 (23%)
		NHL repeat	1068..1107	CDD:271329	10/42 (24%)
		NHL repeat	1112..1151	CDD:271329	7/51 (14%)
		NHL repeat	1157..1183	CDD:271329	6/26 (23%)
nhlrc3	XP_002936773.2	NHL	52..340	CDD:302697	52/243 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D489543at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010