DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mei-P26 and rnf207a

DIOPT Version :9

Sequence 1:	NP_001356936.1	Gene:	mei-P26 / 45775	FlyBaseID:	FBgn0026206	Length:	1310	Species:	Drosophila melanogaster
Sequence 2:	XP_005169403.1	Gene:	rnf207a / 100001767	ZFINID:	ZDB-GENE-120813-7	Length:	209	Species:	Danio rerio

Alignment Length:	173	Identity:	27/173 - (15%)
Similarity:	63/173 - (36%)	Gaps:	44/173 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   286 CDNAHKYMRCFENHHVVRIEDLTKNVHDKLIIHKPVFCPQHVSENLKYYCFTCQVPTCNDCLLSD 350
            |.|..|..|..:. .:.|::|..:.:|..|..|..:.....::|.|:            .|||.|
Zfish    41 CRNFEKSYRSLQT-EIQRLKDEVQEMHRDLTKHHSLINTDTMNEILE------------RCLLID 92

  Fly   351 HKGSDHH-----------------YETATVAEQAVRADLEETLSDTLKKAD-YCNDAGSNLGSAL 397
            .:.:..:                 ::..|..::...|.|.:.|.  ||:.: |.......:|..:
Zfish    93 EQIASQYSAVQTQRTVFEEKWDVTFQRVTNEQEIYEAQLHDLLQ--LKQENSYLTTIARQIGPYI 155

  Fly   398 TELQSQHDTVRQQIEDAYKCYKRMLESIKDQMLNELGRLHSDR 440
            ..:..    |::::|..:       :..::..::...::|.|:
Zfish   156 LSIAK----VKERLEPRF-------QKPENDCIDTTVKIHEDQ 187

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mei-P26	NP_001356936.1	RING_Ubox	158..230	CDD:354325
		BBOX	321..360	CDD:237988	6/55 (11%)
		BBC	369..494	CDD:128778	11/73 (15%)
		NHL_brat_like	913..1186	CDD:271329
		NHL repeat	936..972	CDD:271329
		NHL repeat	983..1025	CDD:271329
		NHL repeat	1028..1064	CDD:271329
		NHL repeat	1068..1107	CDD:271329
		NHL repeat	1112..1151	CDD:271329
		NHL repeat	1157..1183	CDD:271329
rnf207a	XP_005169403.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D489543at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010