Protein Alignment AgaP_AGAP007538 and sip3

DIOPT Version :9

• Sequence 1: XP_001237062.2
• Gene: AgaP_AGAP007538 / 4576491
• VectorBaseID: AGAP007538
• Length: 703
• Species: Anopheles gambiae
• Sequence 2: NP_001263152.1
• Gene: sip3 / 43747
• FlyBaseID: FBgn0039875
• Length: 626
• Species: Drosophila melanogaster
• Alignment Length: 642
• Identity: 144/642 - (22%)
• Similarity: 257/642 - (40%)
• Gaps: 139/642 - (21%)

Mosquito    61 YCCLILLGKSIQKFVFGELRISEQQHMKDKFWNFIFYKFIFVFGVVNVQYLYEVILWVSWFSALG 125
            :..:.:.||.:.|...|.||.:|.:|:.::|| :...:....|.|....:...   :|:.|:.|.
  Fly    49 FVIVFMFGKLLSKIFLGTLRAAEFEHLLERFW-YALTETCLAFTVFRDDFNPR---FVALFTVLL 109

Mosquito   126 FLHLLSQLSKDRFEYLSFSPTTPGW-SHFRLISLLVAILAL----------SGLMVGISIGVGVF 179
            ||.....|:::|.:::..||.. || .|.|:.|||..:..|          |.|:.|.::.:
  Fly   110 FLKSFHWLAEERVDFMERSPVL-GWLFHIRVGSLLTVLGILDYVLLIHAYNSTLVRGPTVQL--- 170

Mosquito   180 FGGFNTFAFMAAECILLSIRTLHVLIRYGMFLHDMRQGGIANESISWDKRGPVAYYIELTFEVAA 244
                 .|.|..|  |||:: .....|:|.:...:||      ....|:.:.....|.||   |..
  Fly   171 -----VFGFEYA--ILLTV-IASTAIKYVLHAAEMR------TDTPWENKAVFLLYTEL---VIG 218

Mosquito   245 LMVELVHYIHMMLWSNI-----FLSMASLVILMQLRYLLNEIQRKIKKHRNYLWVLNHMEKSYPL 304
            |:..:::.:.:::.:.|     |:.......:...|..||::....:..||       |...||.
  Fly   219 LIKVVLYILFVVIMAKIYALPMFVFRPMFFTIRNFRKALNDVIMSRRAIRN-------MNTLYPD 276

Mosquito   305 ASSDDLKQNSDNCAICWEKM-ETARKLPCAHLFHNSCLQSWLEQDTSCPTCRLGL----SVHQNG 364
            |:.::|:|:.:.|.||.|.| ..::||||.|:||.:||:||.::..:||||||.:    :|:...
  Fly   277 ATPEELRQSDNICIICREDMVNHSKKLPCGHIFHTTCLRSWFQRQQTCPTCRLNILRTPTVNSTA 341

Mosquito   365 GPR----------GSPL-------------LPDDIRIDDQDGA---VGGGGGRTANNHFFHFNGS 403
            .||          |:|:             .|....:.|.:.|   |...||:....:|....|.
  Fly   342 MPRQGDEAVAAAAGNPIPAAAGVQPAGGVPPPAPTAVVDGNQARADVNVAGGQALPPNFADLFGD 406

Mosquito   404 RYVSWLPN-------FSVEVTHINSMLRP-------SETLPITAAAVGNHTSQVRNMARHVQEMF 454
              .|.|||       ..:....:..|:.|       ....|:....:....:...:......|..
  Fly   407 --ASGLPNGLPNLAGLQIPPPPVMPMISPFMIPPHFGYLTPLPPPPIPQDLTNFTDEELRAMEGL 469

Mosquito   455 PRYPLSVLIGDLQISRSIEVTIDNI---------LEGRLQVPANSPEDEDEETLGAANVASMAMS 510
            .|   ..::..|::.::|.:.:|:.         |..|||:.|.:|              :.|::
  Fly   470 QR---DHIVQRLKLLQNINLMLDSAGIMMSQYQSLSARLQLTAVTP--------------ATAVN 517

Mosquito   511 GSMDG---DNGDDDDELSGELSTRSLTNSLSASSLSSLSSPAGYEVERGTNIFGNYDALLRDDTV 572
            ||.|.   |..........:|.|..:|.:.:|||.|.........:|   ::..:.|   .||..
  Fly   518 GSADSSVYDMPSTSATAMAQLETHQVTPTAAASSASPTMPAEKVTIE---DLGADAD---EDDIP 576

Mosquito   573 EEISSATSVPLGDR-FSKSPEEREKILQRRKEQLLAMARRRYLEKNKSELNHQPSTS 628
            ...:.|.|:|..|. |.::..|..::.:||.:.|        .|:|||...::.:|:
  Fly   577 STATEAVSIPNSDADFEENSSELGELRKRRLKFL--------EERNKSAATNERTTA 625

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AgaP_AGAP007538	XP_001237062.2	HRD1	49..>370	CDD:227568	87/339 (26%)
		TDT	<99..211	CDD:296283	30/122 (25%)
		zf-RING_2	315..355	CDD:290367	19/40 (48%)
		CUE_AMFR	444..484	CDD:270604	6/48 (13%)
sip3	NP_001263152.1	HRD1	20..>365	CDD:227568	88/347 (25%)
		zf-RING_2	287..328	CDD:290367	19/40 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5243
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D271732at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820