DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment AgaP_AGAP007538 and CG13605

DIOPT Version :9

Sequence 1:	XP_001237062.2	Gene:	AgaP_AGAP007538 / 4576491	VectorBaseID:	AGAP007538	Length:	703	Species:	Anopheles gambiae
Sequence 2:	NP_651214.2	Gene:	CG13605 / 42858	FlyBaseID:	FBgn0039150	Length:	669	Species:	Drosophila melanogaster

Alignment Length:	375	Identity:	74/375 - (19%)
Similarity:	134/375 - (35%)	Gaps:	138/375 - (36%)

- Green bases have known domain annotations that are detailed below.

Mosquito    95 IFYKFI--FVFGVVNVQYLYEVILWVSWFSALGFLHLLSQ-----LSKDRF---------EYLSF 143
            :|:||:  .:.|:|::..|..|:..|: .|....:..|:|     :.:|.|         .:|:.
  Fly   360 LFFKFLHDHLLGIVDLLVLQTVMYNVN-RSVRNQVARLAQKNYAVMVRDTFLVAVVVTVRLFLAT 423

Mosquito   144 SPTTPGWSHFRLI------SLLVAILAL---------------------------SGLMVGISIG 175
            ||..|    |.||      |:.:.:.||                           ..|.| |.:|
  Fly   424 SPPDP----FGLIVPPSRKSVFIEVTALPFHTSSEGDSPTTSSEPIKTNMYKDTYKSLNV-IPLG 483

Mosquito   176 VGVFFGGFNTFAFMAAECILLSIRTLHVLIRYGMFLHDMRQGGIANESISWDKRGPVAYYIELTF 240
            :.::        ::|...:::.:.|:.|.:...|..|.:                       :..
  Fly   484 MLLY--------YIAVSDLIIKLLTMLVKLIITMLPHHL-----------------------MRL 517

Mosquito   241 EVAALMVELVHYIHMML--------WSNIFL--SMASLVI----LMQLRYLLNEIQRKIKKHRNY 291
            :|.|.:..||.||....        |. :||  |.:.|.:    |....||..:|...:::.::.
  Fly   518 KVRARLYVLVEYISQFYRAMTPITQWL-LFLYESYSGLEVVSGGLFSAMYLGAKIFELVERGKSL 581

Mosquito   292 LWVL----NHMEKSYPLASSDDLKQNSDNCAICWEKMETARKLPCAHLFHNSCLQSWLEQDTSCP 352
            ...:    .:::...| .:.|:|......|.||.:...|...|.|.|:|.:.|:|:|.:::.:||
  Fly   582 KKAIVTFRKNIDSERP-PTKDELDAAGALCPICHDAFNTPTVLECGHIFCDECVQTWFKREQTCP 645

Mosquito   353 TCRLGLSVHQNGGPRGSPLLPDDIRIDD---QDGAVGGGGGRTANNHFFH 399
            .||..:|                   ||   |||          :..|||
  Fly   646 MCRAKVS-------------------DDPAWQDG----------STTFFH 666

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AgaP_AGAP007538	XP_001237062.2	HRD1	49..>370	CDD:227568	66/341 (19%)
		TDT	<99..211	CDD:296283	29/160 (18%)
		zf-RING_2	315..355	CDD:290367	13/39 (33%)
		CUE_AMFR	444..484	CDD:270604
CG13605	NP_651214.2	RING	610..651	CDD:238093	15/40 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5243
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D897451at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820