Protein Alignment AgaP_AGAP007538 and Amfr

DIOPT Version :9

• Sequence 1: XP_001237062.2
• Gene: AgaP_AGAP007538 / 4576491
• VectorBaseID: AGAP007538
• Length: 703
• Species: Anopheles gambiae
• Sequence 2: XP_038954087.1
• Gene: Amfr / 361367
• RGDID: 1311551
• Length: 643
• Species: Rattus norvegicus
• Alignment Length: 626
• Identity: 271/626 - (43%)
• Similarity: 381/626 - (60%)
• Gaps: 86/626 - (13%)

Mosquito    36 GAYLKDTASFMATEPFCIWTLINTAYCCLILLGKSIQKFVFGELRISEQQHMKDKFWNFIFYKFI 100
            |..::|.|.::.::...:|.|:|||.|.|:|:.|.||..|||.||:||:||:|||||||||||||
  Rat    67 GPRVRDVAQYLLSDSLFVWVLVNTACCVLMLVAKLIQCIVFGPLRVSERQHLKDKFWNFIFYKFI 131

Mosquito   101 FVFGVVNVQYLYEVILWVSWFSALGFLHLLSQLSKDRFEYLSFSPTTPGWSHFRLISLLVAILAL 165
            |:|||:|||.:.||::|..||:.|.||||:.||.||||||||||||||..||.|::|||:|:| |
  Rat   132 FIFGVLNVQTVEEVVMWCLWFAGLVFLHLMVQLCKDRFEYLSFSPTTPMSSHGRVLSLLIAML-L 195

Mosquito   166 SGLMVGISIGVGVFFGGFNTFAFMAAECILLSIRTLHVLIRYGMFLHDMRQGGIANESISWDKRG 230
            |...:.:...|..:..|.:|.||||||.:|:::||.||::||.:.|.|:...|      :|:.:|
  Rat   196 SCCGLAVVCCVTGYTHGMHTLAFMAAESLLVTVRTAHVILRYVIHLWDLNHEG------TWEGKG 254

Mosquito   231 PVAYYIELTFEVAALMVELVHYIHMMLWSNIFLSMASLVILMQLRYLLNEIQRKIKKHRNYLWVL 295
            ...||.:...|:..|.::|:|:|||:|:.||:||||||||.||||||.:|:||:|::|:|||.|:
  Rat   255 TYVYYTDFVMELMLLSLDLMHHIHMLLFGNIWLSMASLVIFMQLRYLFHEVQRRIRRHKNYLRVV 319

Mosquito   296 NHMEKSYPLASSDDLKQNSDNCAICWEKMETARKLPCAHLFHNSCLQSWLEQDTSCPTCRLGLSV 360
            .:||..:.:|::::|..|:|:|||||:.|:.||||||.||||||||:|||||||||||||:.|::
  Rat   320 GNMEARFAVATAEELAVNNDDCAICWDSMQAARKLPCGHLFHNSCLRSWLEQDTSCPTCRMSLNI 384

Mosquito   361 HQNGGPRGSPLLPDDIR---IDDQDGAVGGGGGR---TANNHFFHFNGSRYVSWLPNFSVEVTHI 419
            ......|      :|.:   :|:....|....||   ..:||||||:|||..||||:|||||.|.
  Rat   385 ADGSRAR------EDHQGENLDENLVPVAAAEGRPRLNQHNHFFHFDGSRIASWLPSFSVEVMHT 443

Mosquito   420 NSMLRPSETLPITAAAVGNHTSQVRNMARHVQEMFPRYPLSVLIGDLQISRSIEVTIDNILEGRL 484
            .::      |.||.|:    .||:..||..:|||||:.|..:::.|||::||:|:|.|||||||:
  Rat   444 TNI------LGITQAS----NSQLNAMAHQIQEMFPQVPYHLVLQDLQMTRSVEITTDNILEGRI 498

Mosquito   485 QVP------------ANSPEDEDEETLGAANVASMAMSGSMDGDNGDDDDELSGELSTRSLTNSL 537
            |||            .|||.:..                      |.|.:|....:.|..:...|
  Rat   499 QVPFPVQRSDSLRPALNSPVERP----------------------GTDLEEGEASVQTERVPLDL 541

Mosquito   538 SASSLSSLSSPAGYEVERGTNIFGNYDALLRDDTVEEISSATSVPLGDRFSKSPEEREKILQRRK 602
            |.....:|...   |||            |....||:..:.     |.|||||.:||:::|.:||
  Rat   542 SPRLEETLDFS---EVE------------LEPVEVEDFEAR-----GSRFSKSADERQRMLVQRK 586

Mosquito   603 EQLLAMARRRYLEKNKSELNHQPSTSATASTSS---TVRHR 640
            :.||..||:|:|.|:..:.........:..|||   |:|.|
  Rat   587 DDLLQQARKRFLNKSSEDDGASERLLPSEGTSSDPVTLRRR 627

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AgaP_AGAP007538	XP_001237062.2	HRD1	49..>370	CDD:227568	173/320 (54%)
		TDT	<99..211	CDD:296283	61/111 (55%)
		zf-RING_2	315..355	CDD:290367	32/39 (82%)
		CUE_AMFR	444..484	CDD:270604	21/39 (54%)
Amfr	XP_038954087.1	HRD1	86..>382	CDD:227568	170/302 (56%)
		RING-H2_AMFR	339..382	CDD:319369	34/42 (81%)
		CUE_AMFR	458..498	CDD:270604	21/39 (54%)
		G2BR	575..600	CDD:375868	11/24 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	280	1.000	Domainoid score	I1667
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H888
Inparanoid	1	1.050	475	1.000	Inparanoid score	I1511
OMA	1	1.010	-	-		QHG55068
OrthoDB	1	1.010	-	-		D271732at33208
OrthoFinder	1	1.000	-	-		FOG0006872
OrthoInspector	1	1.000	-	-		oto215123
Panther	1	1.100	-	-	LDO	PTHR15067
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3836
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	12.080