Protein Alignment AgaP_AGAP007538 and hrd1

DIOPT Version :9

• Sequence 1: XP_001237062.2
• Gene: AgaP_AGAP007538 / 4576491
• VectorBaseID: AGAP007538
• Length: 703
• Species: Anopheles gambiae
• Sequence 2: NP_596376.1
• Gene: hrd1 / 2539900
• PomBaseID: SPBC17D11.02c
• Length: 677
• Species: Schizosaccharomyces pombe
• Alignment Length: 752
• Identity: 149/752 - (19%)
• Similarity: 267/752 - (35%)
• Gaps: 194/752 - (25%)

Mosquito    42 TASFMATE-PFCIWTLINTAYCCLILLGKSIQKFVFGELRISEQQHMKDKFWNFIFYKFIFVFGV 105
            :|:.|.:: |..|...:|...|....:..:::..:||.|:..|.:.:.::||       |.:..:
pombe    30 SATVMISQSPVHITIGLNVCLCLFFAIANALKTLLFGSLQTFELELLYEQFW-------ITLTEI 87

Mosquito   106 VNVQYLYEVILWVSWF---SALGFLHLLSQLSKDRFEYLSFSPTTPGWSHFRLISLLVAILALSG 167
            :....::...:.:|:|   |.|.|..:...:...|.|.|....|...:..|..::....:|::..
pombe    88 MLAITVFREAISISFFMLLSTLMFARVFHSICSFRTERLQIQLTDQRFHIFSRLTCAYFVLSILD 152

Mosquito   168 LMVGISIGVGVFFGGFNTFAFMAAECILLSIRTLHVLIRYGMFLHDMRQGGIANESISWDKRGPV 232
            ..:..........|..:|......|..:|.:.......:..::|::.|     :....||::.
pombe   153 ASLIYLCFTSEHLGDKSTRMLFVCEFSVLLLNLTIEASKLCIYLYEAR-----HLDQVWDEKS-- 210

Mosquito   233 AYYIELTFEVAALMVELVHYIHMMLWSNIFLSMASLVILMQLRYLLNEIQRKIKKHRNYLWVLNH 297
            .|...|  ||....:.|:.|..:.::...::|: .:..:.|:......:.|:|::|..:......
pombe   211 TYLFRL--EVCRDGLRLLAYSLLFMYQFPYVSV-PIYSIRQMYTCFYSLFRRIREHARFRQATRD 272

Mosquito   298 MEKSYPLASSDDLKQNSDNCAICWEKM---------------------ETARKLPCAHLFHNSCL 341
            |...||.|:.:.|..:...|.||.|:|                     .|.::|||.|:.|..||
pombe   273 MNAMYPTATEEQLTNSDRTCTICREEMFHPDHPPENTDEMEPLPRGLDMTPKRLPCGHILHFHCL 337

Mosquito   342 QSWLEQDTSCPTCRLGLSVHQNGGPRGSPLLPDDIRIDDQDGAVGGGGGRTANNHFFHFNGSRYV 406
            ::|||:..:||.||..:..:|: .|.|.|..|
pombe   338 RNWLERQQTCPICRRSVIGNQS-SPTGIPASP--------------------------------- 368

Mosquito   407 SWLPNFSVEVTHINSMLRPSETLPITAAAVG--NHTSQ----------VRN-----MARHVQEMF 454
                  :|..|.|.:.:...:..|.|.|..|  |.::|          |.|     .|.|.|::.
pombe   369 ------NVRATQIATQVPNPQNTPTTTAVPGITNSSNQGDPQASTFNGVPNANSSGFAAHTQDLS 427

Mosquito   455 PRYPLSVLIGD----LQI---------SRSIEVTIDNILEGRLQVPANSPE--DEDEETLGAANV 504
            ...|..:.:.|    |.|         |:|...|          .|:.:|.  |....|.|....
pombe   428 SVIPRRIALRDGWTMLPIPGTRRIPTYSQSTSTT----------NPSATPTTGDPSNSTYGGPQT 482

Mosquito   505 ASMAMSGSMDGDNGDDDDELSG--------------ELSTRSLTNSL-----SASSLSSLSSPAG 550
            ...:      |:|.:.:..::|              .|||.|...||     ||.:....|.|..
pombe   483 FPNS------GNNPNFNRGIAGIVPPGWRLVSSNTQSLSTNSAMTSLYQNASSADNNLGSSLPNV 541

Mosquito   551 YEVERG---TNIFGNYDALLRDDTVEEISSATSVPLGDRFSKSPEEREKILQRRKEQLLAMARRR 612
            ..:.||   :|...|        |....||..|..|.:..:|..|.||.:...|.:
pombe   542 VPLSRGLTQSNETSN--------TFPAASSNISSQLRELHTKIDELRETVSNFRAD--------- 589

Mosquito   613 YLEKNKSELNHQPSTSATASTSSTVRHRNKSCMETTIVESASSSSG-SGSSGNNLSKLNPSLSPS 676
             ....::.||.       ...:|.:..|    ::||..:|..:|:| ||:.|  ......|::.:
pombe   590 -YNSIRTSLNQ-------LEAASGINER----IQTTSADSLLNSNGMSGTEG--FENTQTSITTN 640

Mosquito   677 HHQQRL--SVEQQQPL--DEVQ------QLDHSDSSF 703
            .:|..:  |.:|..|.  ||.:      ||:..|.:|
pombe   641 DNQSSILTSSDQTSPFATDEDRQNSRNVQLETVDENF 677

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AgaP_AGAP007538	XP_001237062.2	HRD1	49..>370	CDD:227568	69/345 (20%)
		TDT	<99..211	CDD:296283	16/114 (14%)
		zf-RING_2	315..355	CDD:290367	18/60 (30%)
		CUE_AMFR	444..484	CDD:270604	11/57 (19%)
hrd1	NP_596376.1	HRD1	1..514	CDD:227568	102/556 (18%)
		zf-RING_2	291..351	CDD:290367	18/59 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5243
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810