Protein Alignment beta'COP and copa

DIOPT Version :9

• Sequence 1: NP_524836.2
• Gene: beta'COP / 45757
• FlyBaseID: FBgn0025724
• Length: 914
• Species: Drosophila melanogaster
• Sequence 2: NP_001001941.2
• Gene: copa / 260439
• ZFINID: ZDB-GENE-020905-2
• Length: 1224
• Species: Danio rerio
• Alignment Length: 996
• Identity: 243/996 - (24%)
• Similarity: 418/996 - (41%)
• Gaps: 221/996 - (22%)

  Fly    10 RLTSRSDRVKCVDLHPAEPWMLCALYNGHVHIMNYENQQMVKDFEVCDVPVRSARFVARKNWILT 74
            :..::|.|||.:..||..||:|.:|:||.:.:.:|....::..|:..|.|||...|..::...::
Zfish     4 KFETKSARVKGLSFHPKRPWILASLHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVS 68

  Fly    75 GSDDMQIRVFNYNTLEKVHSFEAHSDYLRCIAVHPTQPLVLTSSDDMLIKLWNWEKMWACQRVFE 139
            |.||.:|:|:||.....:.:...|.||:|....|...|.:|::|||..|::|||:.. .|..|..
Zfish    69 GGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWILSASDDQTIRIWNWQSR-TCVCVLT 132

  Fly   140 GHTHYVMQIVFNPKDNNTFASASLDRTVKVWQL--------------------------GSNFA- 177
            ||.||||...|:|.: :...|||||:||:||.:                          |::.|
Zfish   133 GHNHYVMCAQFHPSE-DLVVSASLDQTVRVWDISGLRKKNLSPGAVDTEVRGISGVDLFGASDAV 196

  Fly   178 -NFTLEGHEKGVNCVDYYHGGDKPYLISGADDRLVKIWDYQNKTC--VQTLEGHAQNISAVCFHP 239
             ...||||::|||...::  ...|.::||||||.||||.......  :.|..||..|:|...|||
Zfish   197 VKHVLEGHDRGVNWAAFH--PSMPLIVSGADDRQVKIWRMNESKAWELDTCRGHYNNVSCAVFHP 259

  Fly   240 ELPIVLTGSEDGTVRIWHSG------TYRLETCLNYGFERVWTISSMRGTNNVALGYDEGSIIIK 298
            ...::|:.|||.::|:|...      |:|.:      .:|.|.:.:....|..|.|:|.|.::.|
Zfish   260 RQELILSNSEDKSIRVWDMSKRTGVQTFRRD------HDRFWVLGAHPNLNLFAAGHDSGMLVFK 318

  Fly   299 VGREEPAMSMDVVGSKIIWAKHSEMQQVNLKTIADGT--EIKDGERLPVATKDMGACEIYPQTIA 361
            :.||.||.:  |.|:.:.:.|...::|::..:..|..  :::.|.:.||.            :::
Zfish   319 LERERPAYA--VYGNMLYYVKDRFLRQLDFNSSKDTAVMQLRSGSKFPVF------------SMS 369

  Fly   362 HNPNGRFVVVC------GDGEYIIYTSMALRNKAFGSAQE--------FVWALESNEYAIRENNG 412
            :||....|::|      .:..|.:|:.....:.....|.|        .|| :..|.:|:.:...
Zfish   370 YNPAENAVLLCTRATNLENSTYDLYSIPRESDSQNPDAPEGKRSSGLTAVW-VARNRFAVLDRMH 433

  Fly   413 TVRLFRNFKE---RKSFTPEYGAESIYGGYYFG-----VKTSSGLAFYDWETLQLVRRIEV-QPK 468
            :: |.:|.|.   :|...|  ..|.|   :|.|     ::.:.|:..:|.:..:.:..::: :.|
Zfish   434 SL-LIKNLKNEIVKKVQVP--SCEEI---FYAGTGSLLLRDAEGVTLFDVQQKRSLATVKIAKVK 492

  Fly   469 NVFWNESGSLVCLATDDSYFVLGVDTAQVANAVETKEGLEDDGVESAFNVLGEVSECVKTGLWV- 532
            .|.|:...:.|.|....:..:.                  :..:||..|:...:.  ||:|.|.
Zfish   493 YVVWSSDANHVALLAKHAIMIC------------------NKKLESLCNIHENIR--VKSGAWAE 537

  Fly   533 GDCFIYTNSVNRINY-YVGGEIVTVSHLDRTMYLLGYVPKDNRIYLGDKELNVISFC----LQLS 592
            .:.||||.| |.|.| ...|:...:..||..:|:...  :.|.:|..|:|      |    |.:.
Zfish   538 NEVFIYTTS-NHIKYALTSGDHGIIRTLDLPIYVTRV--RGNSVYCLDRE------CRPRVLNID 593

  Fly   593 VLEY--QTAVMRRDFERADVVLPTIPKEHRTR--------VAHFLEKQGFKSQALQVSTDADHKF 647
            ..||  :.|::.|.:|.   ||      |..|        :..:|:|:|:...||....|...:|
Zfish   594 PTEYRFKLALVNRKYEE---VL------HMVRNAKLVGQSIIAYLQKKGYPEVALHFVKDEKTRF 649

  Fly   648 DLALQIGDLEIALKLARESENSQKWSQLADVASSKNNMSLVKECMQKANDLSGLLLLSTASGD-- 710
            .|||:.|::|:||:.|:..:....|.:|.:.|..:.:..:|:.|.|:..:...|..|...:|:
Zfish   650 SLALECGNIEVALEAAKALDERSCWERLGEAALLQGHHQVVEMCYQRTKNFDKLTFLYLITGNLT 714

  Fly   711 --AQLLEVVGAAGSAQGHHNLAFLSAFLRSDVERCLEILIETNRLPEAAFFARTYLPSQ----MS 769
              .:::::........||:.    .|....||...:.||....:...|...|.|:...:    :.
Zfish   715 KLRKMMKIAEIRKDMSGHYQ----GALYLGDVSERVRILKNCGQKSLAYLTAATHGMDEEAEALK 775

  Fly   770 RIVELWREKLGKVNEKAGQSLADPAQYTNLFPGLGDALRVEQHLQEERARKAPARLAANLPLNSE 834
            ...:|.:|.:.:|:..| |.|..|       |.:..                   |..|.||.:.
Zfish   776 ETFDLEKEMVPEVDPNA-QLLQPP-------PPINP-------------------LDTNWPLLTV 813

  Fly   835 RHPLQELFAAEQGAAGQ---------------------HLEEKVKPAYVPAQAVVSSSQVAEPTS 878
            .....|...|.:|.|||                     ||:|   ..::.||..:..    |...
Zfish   814 SKGFFEGAIAAKGRAGQMVADLDMDAPGGEGWGEDAELHLDE---DGFMDAQEGLGD----EGAI 871

  Fly   879 AADD------DDDLDL--EID 891
            ..||      ::||||  |:|
Zfish   872 GKDDGGGWDVEEDLDLPPELD 892

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
beta'COP	NP_524836.2	WD40	8..378	CDD:225201	119/411 (29%)
		WD40	8..297	CDD:238121	102/322 (32%)
		WD40 repeat	20..55	CDD:293791	10/34 (29%)
		WD40 repeat	61..97	CDD:293791	9/35 (26%)
		WD40 repeat	102..139	CDD:293791	13/36 (36%)
		WD40 repeat	146..182	CDD:293791	14/63 (22%)
		WD40 repeat	188..226	CDD:293791	14/39 (36%)
		Coatomer_WDAD	321..765	CDD:281977	101/488 (21%)
copa	NP_001001941.2	WD40	<2..317	CDD:225201	102/322 (32%)
		WD40	9..318	CDD:238121	102/318 (32%)
		WD40 repeat	15..49	CDD:293791	10/33 (30%)
		WD40 repeat	55..91	CDD:293791	9/35 (26%)
		WD40 repeat	96..132	CDD:293791	13/36 (36%)
		WD40 repeat	139..202	CDD:293791	14/63 (22%)
		WD40 repeat	208..241	CDD:293791	13/34 (38%)
		WD40 repeat	249..278	CDD:293791	11/28 (39%)
		Coatomer_WDAD	339..766	CDD:281977	101/487 (21%)
		COPI_C	816..1218	CDD:284395	20/84 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D122926at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920