DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment FarO and CG34342

DIOPT Version :9

Sequence 1:	NP_652021.1	Gene:	FarO / 45707	FlyBaseID:	FBgn0023550	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_001097509.3	Gene:	CG34342 / 5740152	FlyBaseID:	FBgn0085371	Length:	572	Species:	Drosophila melanogaster

Alignment Length:	532	Identity:	137/532 - (25%)
Similarity:	241/532 - (45%)	Gaps:	84/532 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 EFFEDSEIFVTGGSGVVGKALVEKLLRSCNVRRIYVLLRPRKQLTAEQRLVRLRQATVFHVLAVQ 75
            :|:.::.:.:|||:|.|||.|.||||||..:|:||:|:|.:..::.::||......::|:.:..:
  Fly    72 DFYSNATVLITGGTGFVGKVLTEKLLRSFGLRKIYMLIRSKDNMSVQERLKGFFNESIFNRMREE 136

  Fly    76 KPEELDKIVAVPGDVSLPGLGIDPSMMQRMKG-VSLVYHCAATVRFDEPLREAVRLNVGGTLEAL 139
            .|:.|.|:..:..|.|...|.||.:....:.. |.:|::..|:|:|:|.|.:|:.:||.||.:.|
  Fly   137 SPQLLAKVHPIRADYSAIDLDIDSADRAMLSSEVQIVFNVVASVKFNEKLSDAIDINVLGTKKIL 201

  Fly   140 KFAETLPQLRAFIHVSTFYSNPYLTRVEPKYYSSPMDWRLCLRMIDDVADDGMLNALTRKLIMGF 204
            .....:..|::|:|:||.|.|.....::.:.|.:.:.:...:: |....||..|..:...||...
  Fly   202 DLVMEMKHLKSFVHISTLYCNCNRKFIKEQVYENEIGYEKIMQ-IYRTFDDETLEKMRHCLIGQM 265

  Fly   205 PNTYTFTKNLAESLVNDYRHRLPVIVYRPSIVLFAVEDPSPGFSPSLMGAMGLFALVGAGILKTV 269
            |||||.||..||:|||.....:|..::||.||:...:||.||::.:|.|..||......|:::.:
  Fly   266 PNTYTMTKKCAENLVNHRAFHMPAGIFRPPIVMSTYKDPFPGWTDNLYGPSGLCTWSARGLVRCI 330

  Fly   270 YLGKDIRLDITPQDIGIKSMLCYTKMGYDIYRQ--------GPPADLPVF--------------- 311
            |.....:.::.|.|..:.:|:.   ..:||.|:        ...::|||:
  Fly   331 YGKASCKANMVPADYVVNAMIA---TAWDIARRFKLRESKVDGKSELPVYNYVSDANNITWGQYM 392

  Fly   312 -LSSSCTHVPHTFTQIAEQMDTLDLWRDVAFEKNLMIPGCHYTDKRWAYQFLV-----------F 364
             ||....|.|                    |:|.|           |.:.:::           |
  Fly   393 HLSRKGFHEP--------------------FDKAL-----------WCFSYVIIPSKPLHCAIAF 426

  Fly   365 TKQILPALILDLLLRIFGQKPVLMSAVRKAYQTLEVMQPFMFNNWD--SPGVSDMETLSKHGEGS 427
            ....:||.||||:..:.|||.:...|..|..:.:::|..|....|.  ...:.::..|....|.|
  Fly   427 FLHNIPAYILDLIAMVTGQKRIYAKAYGKISRIIDMMAWFGLKEWKFAHRNIDELNELLPREERS 491

  Fly   428 A--FNFDAFNHPDIHGLVIQSCSNMLHSIRTHLLRE--DPKTLERSKRILRIKVFLYRLLRLFLL 488
            .  ||....|..:..       .:.|..||.:..::  :...|::.:.|.|..:.|:.||:....
  Fly   492 VLQFNIATINWSEYF-------RSYLSGIRRYFFKDSANDNKLQQRRTIYRRMLILHTLLKTTFG 549

  Fly   489 YKLILWLWRSYL 500
            ..||:.:.|.||
  Fly   550 LSLIMCMLRVYL 561

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FarO	NP_652021.1	FAR-N_SDR_e	18..328	CDD:187547	97/334 (29%)
FarO	NP_652021.1	FAR_C	379..>410	CDD:296071	7/30 (23%)
CG34342	NP_001097509.3	PLN02996	70..519	CDD:215538	126/488 (26%)
		FAR-N_SDR_e	78..397	CDD:187547	95/322 (30%)
		Sterile	429..519	CDD:281068	23/96 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466749
Domainoid	1	1.000	159	1.000	Domainoid score	I1277
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D221518at33208
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	1	1.000	-	-		mtm964
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11011
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X145
	8	7.950