Protein Alignment FarO and FAR2

DIOPT Version :9

• Sequence 1: NP_652021.1
• Gene: FarO / 45707
• FlyBaseID: FBgn0023550
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: XP_011519049.1
• Gene: FAR2 / 55711
• HGNCID: 25531
• Length: 535
• Species: Homo sapiens
• Alignment Length: 506
• Identity: 151/506 - (29%)
• Similarity: 255/506 - (50%)
• Gaps: 44/506 - (8%)

  Fly    12 FFEDSEIFVTGGSGVVGKALVEKLLR-SCNVRRIYVLLRPRKQLTAEQRLVRLRQATVFHVLAVQ 75
            |:....|.:||.:|.:||.|:|||.| |.:::.||:|:||:...|.:||:.::..:.:|..:...
Human    27 FYGGKSILITGATGFLGKVLMEKLFRTSPDLKVIYILVRPKAGQTLQQRVFQILDSKLFEKVKEV 91

  Fly    76 KPEELDKIVAVPGDVSLPGLGIDPSMMQRMKG-VSLVYHCAATVRFDEPLREAVRLNVGGTLEAL 139
            .|...:||.|:..|::.....|....||.:.. .::::|||||||||:.||.||:|||..|.:.|
Human    92 CPNVHEKIRAIYADLNQNDFAISKEDMQELLSCTNIIFHCAATVRFDDTLRHAVQLNVTATRQLL 156

  Fly   140 KFAETLPQLRAFIHVSTFYSNPYLTRVEPKYYSSPMDWRLCLRMIDDV--ADDGMLNALTRKLIM 202
            ..|..:|:|.||||:||.|||..|..::...|..|::.:   ::||.:  .||.:::.:|.|||.
Human   157 LMASQMPKLEAFIHISTAYSNCNLKHIDEVIYPCPVEPK---KIIDSLEWLDDAIIDEITPKLIR 218

  Fly   203 GFPNTYTFTKNLAESLVNDYRHRLPVIVYRPSIVLFAVEDPSPGFSPSLMGAMGLFALVGAGILK 267
            .:||.||:||.|.|.:|......|.:.:.|||||....::|.||:..::.|..|:....|.|.|:
Human   219 DWPNIYTYTKALGEMVVQQESRNLNIAIIRPSIVGATWQEPFPGWVDNINGPNGIIIATGKGFLR 283

  Fly   268 TVYLGKDIRLDITPQDIGIKSMLC---YTKMGYDIYRQGPPADLPVFLSSSCTHVPHTFTQIAEQ 329
            .:........|:.|.|..:..||.   ||.    ::|   |....|:..:|....|..:.::..|
Human   284 AIKATPMAVADVIPVDTVVNLMLAVGWYTA----VHR---PKSTLVYHITSGNMNPCNWHKMGVQ 341

  Fly   330 MDTLDLWRDVAFEKNLMIPGCHYTDKRWAYQFLVFTKQILPALILDLLLRIFGQKPVLMSAVRKA 394
            :  |..:..:.||:....|..::|...:..|:........||:|.|..||:.|:||.:...:.:.
Human   342 V--LATFEKIPFERPFRRPNANFTSNSFTSQYWNAVSHRAPAIIYDCYLRLTGRKPRMTKLMNRL 404

  Fly   395 YQTLEVMQPFMFNNWDSPGVSD---METLSKHGEGSAFNFDA--FNHPDIHGLVIQSCSNMLHSI 454
            .:|:.:::.|:..:|:....:.   |..||...: ..||||.  .|.       ::...|.:..:
Human   405 LRTVSMLEYFINRSWEWSTYNTEMLMSELSPEDQ-RVFNFDVRQLNW-------LEYIENYVLGV 461

  Fly   455 RTHLLRED----PKTLERSKRILRIKVFLYRLLRLFLLYKLILWLWRSYLA 501
            :.:||:||    ||..:|.||:..|. :|:. ..|||:      .||..:|
Human   462 KKYLLKEDMAGIPKAKQRLKRLRNIH-YLFN-TALFLI------AWRLLIA 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FarO	NP_652021.1	FAR-N_SDR_e	18..328	CDD:187547	105/316 (33%)
		FAR_C	379..>410	CDD:296071	6/30 (20%)
FAR2	XP_011519049.1	PLN02996	22..467	CDD:215538	135/459 (29%)
		FAR-N_SDR_e	31..335	CDD:187547	105/313 (34%)
		Sterile	377..467	CDD:281068	22/97 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165157501
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3320
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D221518at33208
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100550
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X145
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.650