DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment FarO and CG4770

DIOPT Version :9

Sequence 1:	NP_652021.1	Gene:	FarO / 45707	FlyBaseID:	FBgn0023550	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_650848.1	Gene:	CG4770 / 42375	FlyBaseID:	FBgn0038751	Length:	490	Species:	Drosophila melanogaster

Alignment Length:	499	Identity:	143/499 - (28%)
Similarity:	246/499 - (49%)	Gaps:	45/499 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 EFFEDSEIFVTGGSGVVGKALVEKLLRSC-NVRRIYVLLRPRKQLTAEQRLVRLRQATVFHVLAV 74
            :.::|:.:|:||.:|.|||:|:||||.|. .::|||:|:||:..:|.|:|.....|..:|..:..
  Fly    14 DIYQDAVVFITGATGFVGKSLLEKLLWSFPQIKRIYMLIRPKGGVTVEERFRGFLQNPIFERIKS 78

  Fly    75 QKPEELDKIVAVPGDVSLPGLGIDPSMMQRM-KGVSLVYHCAATVRFDEPLREAVRLNVGGTLEA 138
            :.|.:|.||....|::....||::.|....: ..|::::|.||||||:|.|:.:.|:|...|...
  Fly    79 EHPTQLKKIFHFSGNIEDDNLGLNESDRSVLCAEVNIIFHSAATVRFNECLKVSARVNSQATYNL 143

  Fly   139 LKFAETLPQLRAFIHVSTFYSNPYLTRVEPKYYSS--PMDWRLCLRMIDDVADDGMLNALTRKLI 201
            |:....:|.||:|::|||.|.||....|:.:.|.:  |:|||..|.....:.|| .||.|...:.
  Fly   144 LELCRQMPYLRSFLYVSTAYCNPGRKYVDEQVYPTMPPVDWRQFLSATQKIPDD-YLNRLADYIK 207

  Fly   202 MGFPNTYTFTKNLAESLVNDYRHRLPVIVYRPSIVLFAVEDPSPGFSPSLMGAMGLFALVGAGIL 266
            ....|||||||::||.:||.|:..:|:::.|||||..|..:|.||:..::....|:...:|.|.:
  Fly   208 GPHVNTYTFTKSIAEQIVNAYKDVIPIVIVRPSIVTAAYREPYPGWIDNIQAISGIMMEIGKGGI 272

  Fly   267 KTVYLGKDIRLDITPQDIGIKSMLCY---TKMGYDIYRQGPPADLPVFLSSSCTHVPHTFTQIAE 328
            .::...||:..||.|.|..:.:|:..   .|:|          .|.:..::|....|.|:..:.|
  Fly   273 SSILGNKDLICDIIPVDFVVNAMIMMVGKAKLG----------SLSICNATSGVTNPITWQHLGE 327

  Fly   329 QMDTLDLWRDVAFEKNLMIPGCHYTDKRWAYQFLVFTKQILPALILDLLLRIFGQKPVLMSAVRK 393
            .  |:...|.....:.:|.|...|....:.::..|:....:|||::||...:..||..|::.:.|
  Fly   328 L--TMKWSRIYPTRRMIMFPNFKYRCSAFNHELAVWVLHFVPALLMDLQTLLLAQKKRLVTPIAK 390

  Fly   394 AY-QTLEVMQPFMFNNWDSPGVSDMETLSKHGEGSAFNFDAFNHPDIHGLVIQSCSNMLHS--IR 455
            .: |.......|..|.|          :.|:  .|.|.|........:..:..:...|.:.  :|
  Fly   391 KFRQACLAGSFFSLNEW----------IFKN--KSRFYFKEMIENGTYPTLYWNLEEMDYDEYVR 443

  Fly   456 THL------LREDPKTLERSK----RILRIKVFLYRLLRLFLLY 489
            .|:      |..:..|::.:|    ||....:||:.:..:.|:|
  Fly   444 RHMIGINKYLHREKFTVDSNKFMVTRIYWFWIFLHLMFYMMLVY 487

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FarO	NP_652021.1	FAR-N_SDR_e	18..328	CDD:187547	106/316 (34%)
FarO	NP_652021.1	FAR_C	379..>410	CDD:296071	7/31 (23%)
CG4770	NP_650848.1	WcaG	21..358	CDD:223528	112/349 (32%)
		FAR-N_SDR_e	21..337	CDD:187547	109/328 (33%)
		Sterile	364..455	CDD:281068	21/102 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466753
Domainoid	1	1.000	159	1.000	Domainoid score	I1277
eggNOG	1	0.900	-	-		E1_COG3320
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D221518at33208
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	1	1.000	-	-		mtm964
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11011
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X145
	9	8.850