DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment FarO and CG17562

DIOPT Version :9

Sequence 1:	NP_652021.1	Gene:	FarO / 45707	FlyBaseID:	FBgn0023550	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_650566.1	Gene:	CG17562 / 42021	FlyBaseID:	FBgn0038449	Length:	499	Species:	Drosophila melanogaster

Alignment Length:	516	Identity:	141/516 - (27%)
Similarity:	249/516 - (48%)	Gaps:	54/516 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 EMEEFFEDSEIFVTGGSGVVGKALVEKLLRSCNVRRIYVLLRPRKQLTAEQRLVRLRQATVFHVL 72
            :::..|....:|:||.:|.:||.::|||||:..|:|||||:||::.:..:.|::...:..||.:|
  Fly     4 DIQRCFRSKTVFLTGATGFLGKVVIEKLLRTTEVKRIYVLIRPKRGVEIKDRIITWSKDAVFELL 68

  Fly    73 AVQKPEELDKIVAVPGDVSLPGLGIDPSMMQRMKG-VSLVYHCAATVRFDEPLREAVRLNVGGTL 136
            ...|||.|.::..:.||.....|||..:..:.:.. |.:|.|.||||||:|||..|:.:|...|.
  Fly    69 LKSKPEALQRVCPIAGDCLDFDLGISENDRRLLASEVQIVIHGAATVRFNEPLHVALAINTRATK 133

  Fly   137 EALKFAETLPQLRAFIHVSTFYSNPYLTRVEPKYYSSPMDWRLC-----LRMIDDVADDGMLNAL 196
            ..::.|:.:.||.||:||||.:||..:..::..:|...::   |     |.|.:.::|: :|:.:
  Fly   134 LMIQLAKEMRQLEAFVHVSTAFSNCVIYNIKENFYPEHLN---CSSDKVLAMAELMSDE-LLDNM 194

  Fly   197 TRKLIMGFPNTYTFTKNLAESLVNDYRHRLPVIVYRPSIVLFAVEDPSPGFSPSLMGAMGLFALV 261
            .:.|:..||||||:||.|||.::......||:.::||::::.|.::|..|:..::.|.|.:...|
  Fly   195 EQALLGSFPNTYTYTKALAEDVILKEAGGLPLCIFRPAVIIAAHKEPISGWIDNMYGPMAILFGV 259

  Fly   262 GAGILKTVYLGKDIRLDITPQDIGIKSMLCYT--------KMGYD----IYRQGPPADLPVFLSS 314
            ..|:|:...:.......:.|.|......|..|        :||..    ||:..|      ...:
  Fly   260 ARGVLRIATIDHHAEASLVPVDYCANLTLACTWKTIVEGNEMGTQETPLIYQLAP------IEQN 318

  Fly   315 SCTH---VPHTFTQIAEQMDTLDLWRDVAFEKNLMIPGCHYTDKRWAYQFLVFTKQILPALILDL 376
            ..||   :.|          .||...:....|.:..|..|.....|.:....|....|||...||
  Fly   319 KITHGEFIRH----------ALDGRTNCPLTKMIWYPFIHCITVPWLFPLAAFFYHTLPAYFFDL 373

  Fly   377 LLRIFGQKPVLMSAVRKAYQTLEVMQPFMFNNW--DSPGVSDMETLSKHGEGSAFNFD--AFNHP 437
            .|.:.|:||.|:...:|.::||.::.||...:|  |......:.......:...:.||  :.|..
  Fly   374 ALWLSGRKPRLVKVYQKIHKTLGILGPFACKSWRFDMRNTDHLRQQMSEEDRRIYYFDMVSLNWK 438

  Fly   438 DIHGLVIQSCSNMLHSIRTHLLRE--DPKTLERSKRILRIKVFLYRLLRLFLLYKLILWLW 496
            :   ..:|:    |..:|..|..|  .|:::.:.|::::....|:.:|:..|.:..:|.||
  Fly   439 E---YFVQA----LRGMRQFLGNEAPTPESIAQGKKLIKRLKLLHHILQGVLCFVALLALW 492

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FarO	NP_652021.1	FAR-N_SDR_e	18..328	CDD:187547	100/330 (30%)
FarO	NP_652021.1	FAR_C	379..>410	CDD:296071	10/32 (31%)
CG17562	NP_650566.1	PLN02996	10..442	CDD:215538	127/454 (28%)
		FAR-N_SDR_e	12..329	CDD:187547	100/336 (30%)
		FAR_C	362..452	CDD:176924	23/96 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466748
Domainoid	1	1.000	159	1.000	Domainoid score	I1277
eggNOG	1	0.900	-	-		E1_COG3320
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG26995
OrthoDB	1	1.010	-	-		D221518at33208
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	1	1.000	-	-		mtm964
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11011
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X145
	10	9.860